Tourette Syndrome

Common Name(s)

Tourette Syndrome

Tourette syndrome is a disorder of the nervous system that causes a person to make repeated and uncontrolled (involuntary) movements and sounds (vocalizations) called tics. Tourette syndrome is named for Georges Gilles de la Tourette, who first described this disorder in 1885. There is strong evidence that Tourette syndrome is passed down through families, although the gene has not yet been found. The syndrome may be linked to problems in certain areas of the brain, and the chemical substances (dopamine, serotonin, and norepinephrine) that help nerve cells talk to one another. Tourette syndrome can be either severe or mild. It is estimated that about 1% of the population has Tourette syndrome. Many people with very mild tics may not be aware of them and never seek medical help.   Tourette syndrome is four times as likely to occur in boys as in girls.   Although Tourette syndrome can be a chronic condition with symptoms lasting a lifetime, most people with the condition experience their worst symptoms in their early teens, with improvement occurring in the late teens and continuing into adulthood.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Tourette Syndrome" for support, advocacy or research.

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CNS Foundation

CNS Foundation's Mission is Three-fold: - Expedite scientific research to find treatments and cures for the more than 14 million children living with some form of neurological disorder - Provide families and health care professionals with up-to-date information and resources on the latest discoveries in pediatric neurology - Educate the public, and public officials, on the critical importance of funding pediatric neurological disorder research

http://www.cnsfoundation.org

Last Updated: 12 Oct 2013

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International OCD Foundation

Founded by a group of people with OCD in 1986, the International OCD Foundation (IOCDF) is an international not-for-profit organization made up of people with Obsessive Compulsive Disorder (OCD) and related disorders, as well as their families, friends, professionals and others. The mission and goals of the IOCDF are to: Educate the public and professionals about OCD in order to raise awareness and improve the quality of treatment provided; Support research into the cause of, and effective treatments for, OCD and related disorders; Improve access to resources for those with OCD and their fam

http://www.ocfoundation.org

Last Updated: 19 Feb 2013

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Movement Disorder Society

The Movement Disorder Society (MDS) is an international professional society of clinicians, scientists, and other healthcare professionals, who are interested in Parkinson's disease, related neurodegenerative and neurodevelopmental disorders, hyperkinetic movement disorders, and abnormalities in muscle tone and motor control.

www.movementdisorders.org

Last Updated: 16 Jan 2013

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National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

http://www.nami.org

Last Updated: 29 Jan 2013

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Tourette Syndrome Association, Inc.

Founded in 1972, TSA is the only national voluntary non-profit membership organization whose mission is to identify the cause, find the cure and control the effects of Tourette Syndrome through education, research and service.

http://tsa-usa.org

Last Updated: 11 Apr 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Tourette Syndrome" for support, advocacy or research.

Logo
CNS Foundation

CNS Foundation's Mission is Three-fold: - Expedite scientific research to find treatments and cures for the more than 14 million children living with some form of neurological disorder - Provide families and health care professionals with up-to-date information and resources on the latest discoveries in pediatric neurology - Educate the public, and public officials, on the critical importance of funding pediatric neurological disorder research

http://www.cnsfoundation.org

Last Updated: 12 Oct 2013

View Details
International OCD Foundation

Founded by a group of people with OCD in 1986, the International OCD Foundation (IOCDF) is an international not-for-profit organization made up of people with Obsessive Compulsive Disorder (OCD) and related disorders, as well as their families, friends, professionals and others. The mission and goals of the IOCDF are to: Educate the public and professionals about OCD in order to raise awareness and improve the quality of treatment provided; Support research into the cause of, and effective treatments for, OCD and related disorders; Improve access to resources for those with OCD and their fam

http://www.ocfoundation.org

Last Updated: 19 Feb 2013

View Details
Movement Disorder Society

The Movement Disorder Society (MDS) is an international professional society of clinicians, scientists, and other healthcare professionals, who are interested in Parkinson's disease, related neurodegenerative and neurodevelopmental disorders, hyperkinetic movement disorders, and abnormalities in muscle tone and motor control.

www.movementdisorders.org

Last Updated: 16 Jan 2013

View Details
National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

http://www.nami.org

Last Updated: 29 Jan 2013

View Details
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Tourette Syndrome Association, Inc.

Founded in 1972, TSA is the only national voluntary non-profit membership organization whose mission is to identify the cause, find the cure and control the effects of Tourette Syndrome through education, research and service.

http://tsa-usa.org

Last Updated: 11 Apr 2013

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Tourette Syndrome" returned 174 free, full-text research articles on human participants. First 3 results:

Tourette syndrome and chronic tic disorder are associated with lower socio-economic status: findings from the Avon Longitudinal Study of Parents and Children cohort.
 

Author(s): Laura L Miller, Jeremiah M Scharf, Carol A Mathews, Yoav Ben-Shlomo

Journal: Dev Med Child Neurol. 2014 Feb;56(2):157-63.

 

Only a few studies have examined the relationship between Tourette syndrome or chronic tic disorder and socio-economic status (SES). Existing studies are primarily cross-sectional, arise from specialty clinics, and use single measures of SES. In this study we examine this relationship ...

Last Updated: 16 Jan 2014

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Brain mechanisms for prepulse inhibition in adults with Tourette syndrome: initial findings.
 

Author(s): Nazlee Zebardast, Michael J Crowley, Michael H Bloch, Linda C Mayes, Brent Vander Wyk, James F Leckman, Kevin A Pelphrey, James E Swain

Journal: Psychiatry Res. 2013 Oct;214(1):33-41.

 

Prepulse inhibition (PPI) of the startle reflex is disrupted in a number of developmental neuropsychiatric disorders, including Tourette syndrome (TS). This disruption is hypothesized to reflect abnormalities in sensorimotor gating. We applied whole-brain functional magnetic resonance ...

Last Updated: 2 Sep 2013

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[Tics and Tourette syndrome in literature, cinema and television].
 

Author(s): Susana Collado-Vázquez, Jesús M Carrillo

Journal: Rev Neurol. 2013 Aug;57(3):123-33.

 

Different neurological diseases have often been portrayed in literature, cinema and television. Tics and Tourette syndrome, for example, are commonly represented from different perspectives, which are sometimes very realistic but in some cases are used for more dramatic purposes or ...

Last Updated: 24 Jul 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Tourette Syndrome" returned 21 free, full-text review articles on human participants. First 3 results:

The effectiveness of habit reversal therapy in the treatment of Tourette syndrome and other chronic tic disorders: a systematic review.
 

Author(s): Neeladri Dutta, Andrea E Cavanna

Journal: Funct. Neurol.. ;28(1):7-12.

 

Tourette syndrome (TS) is a neurodevelopmental disorder characterized by multiple tics, which can require active intervention. It is recognized that behavioral techniques, especially habit reversal therapy (HRT), can offer an effective alternative or complement to pharmacotherapy ...

Last Updated: 4 Jun 2013

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Pathogenetic model for Tourette syndrome delineates overlap with related neurodevelopmental disorders including Autism.
 

Author(s): R A Clarke, S Lee, V Eapen

Journal:

 

Tourette syndrome (TS) is a highly heritable neuropsychiatric disorder characterised by motor and vocal tics. Despite decades of research, the aetiology of TS has remained elusive. Recent successes in gene discovery backed by rapidly advancing genomic technologies have given us new ...

Last Updated: 5 Sep 2012

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Deep brain stimulation for Tourette syndrome: target selection.
 

Author(s): Ashwin Viswanathan, Joohi Jimenez-Shahed, José Fidel Baizabal Carvallo, Joseph Jankovic

Journal: Stereotact Funct Neurosurg. 2012 ;90(4):213-24.

 

Tourette syndrome (TS) is a complex neurological disorder manifested chiefly by motor and phonic tics and a variety of behavioral comorbidities, including attention disorder, obsessive-compulsive disorder and impulse control problems. Surgical treatment is increasingly considered ...

Last Updated: 21 Aug 2012

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Tourette Syndrome Deep Brain Stimulation
 

Status: Not yet recruiting

Condition Summary: Tourette Syndrome

 

Last Updated: 24 Mar 2014

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MRI Study of Tic Remission in Tourette Syndrome
 

Status: Recruiting

Condition Summary: Tourette Syndrome

 

Last Updated: 1 Jun 2012

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Developing Cognitive Training for Tourette Syndrome
 

Status: Recruiting

Condition Summary: Tourette Syndrome; Chronic Tic Disorders

 

Last Updated: 1 Nov 2013

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