Tourette Syndrome

Common Name(s)

Tourette Syndrome

Tourette syndrome is a disorder of the nervous system that causes a person to make repeated and uncontrolled (involuntary) movements and sounds (vocalizations) called tics. Tourette syndrome is named for Georges Gilles de la Tourette, who first described this disorder in 1885. There is strong evidence that Tourette syndrome is passed down through families, although the gene has not yet been found. The syndrome may be linked to problems in certain areas of the brain, and the chemical substances (dopamine, serotonin, and norepinephrine) that help nerve cells talk to one another. Tourette syndrome can be either severe or mild. It is estimated that about 1% of the population has Tourette syndrome. Many people with very mild tics may not be aware of them and never seek medical help.   Tourette syndrome is four times as likely to occur in boys as in girls.   Although Tourette syndrome can be a chronic condition with symptoms lasting a lifetime, most people with the condition experience their worst symptoms in their early teens, with improvement occurring in the late teens and continuing into adulthood.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Tourette Syndrome" for support, advocacy or research.

Logo
CNS Foundation

CNS Foundation's Mission is Three-fold: - Expedite scientific research to find treatments and cures for the more than 14 million children living with some form of neurological disorder - Provide families and health care professionals with up-to-date information and resources on the latest discoveries in pediatric neurology - Educate the public, and public officials, on the critical importance of funding pediatric neurological disorder research

Last Updated: 12 Oct 2013

View Details
International OCD Foundation

Founded by a group of people with OCD in 1986, the International OCD Foundation (IOCDF) is an international not-for-profit organization made up of people with Obsessive Compulsive Disorder (OCD) and related disorders, as well as their families, friends, professionals and others. The mission and goals of the IOCDF are to: Educate the public and professionals about OCD in order to raise awareness and improve the quality of treatment provided; Support research into the cause of, and effective treatments for, OCD and related disorders; Improve access to resources for those with OCD and their fam

Last Updated: 19 Feb 2013

View Details
Movement Disorder Society

The Movement Disorder Society (MDS) is an international professional society of clinicians, scientists, and other healthcare professionals, who are interested in Parkinson's disease, related neurodegenerative and neurodevelopmental disorders, hyperkinetic movement disorders, and abnormalities in muscle tone and motor control.

Last Updated: 5 May 2014

View Details
National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

Last Updated: 29 Jan 2013

View Details
Tourette Syndrome Association, Inc.

Founded in 1972, TSA is the only national voluntary non-profit membership organization whose mission is to identify the cause, find the cure and control the effects of Tourette Syndrome through education, research and service.

Last Updated: 29 Apr 2014

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Tourette Syndrome" for support, advocacy or research.

Logo
CNS Foundation

CNS Foundation's Mission is Three-fold: - Expedite scientific research to find treatments and cures for the more than 14 million children living with some form of neurological disorder - Provide families and health care professionals with up-to-date information and resources on the latest discoveries in pediatric neurology - Educate the public, and public officials, on the critical importance of funding pediatric neurological disorder research

http://www.cnsfoundation.org

Last Updated: 12 Oct 2013

View Details
International OCD Foundation

Founded by a group of people with OCD in 1986, the International OCD Foundation (IOCDF) is an international not-for-profit organization made up of people with Obsessive Compulsive Disorder (OCD) and related disorders, as well as their families, friends, professionals and others. The mission and goals of the IOCDF are to: Educate the public and professionals about OCD in order to raise awareness and improve the quality of treatment provided; Support research into the cause of, and effective treatments for, OCD and related disorders; Improve access to resources for those with OCD and their fam

http://www.ocfoundation.org

Last Updated: 19 Feb 2013

View Details
Movement Disorder Society

The Movement Disorder Society (MDS) is an international professional society of clinicians, scientists, and other healthcare professionals, who are interested in Parkinson's disease, related neurodegenerative and neurodevelopmental disorders, hyperkinetic movement disorders, and abnormalities in muscle tone and motor control.

http://www.movementdisorders.org/MDS.htm

Last Updated: 5 May 2014

View Details
National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

http://www.nami.org

Last Updated: 29 Jan 2013

View Details
Tourette Syndrome Association, Inc.

Founded in 1972, TSA is the only national voluntary non-profit membership organization whose mission is to identify the cause, find the cure and control the effects of Tourette Syndrome through education, research and service.

http://tsa-usa.org

Last Updated: 29 Apr 2014

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Tourette Syndrome" returned 179 free, full-text research articles on human participants. First 3 results:

Tourette syndrome and chronic tic disorder are associated with lower socio-economic status: findings from the Avon Longitudinal Study of Parents and Children cohort.
 

Author(s): Laura L Miller, Jeremiah M Scharf, Carol A Mathews, Yoav Ben-Shlomo

Journal: Dev Med Child Neurol. 2014 Feb;56(2):157-63.

 

Only a few studies have examined the relationship between Tourette syndrome or chronic tic disorder and socio-economic status (SES). Existing studies are primarily cross-sectional, arise from specialty clinics, and use single measures of SES. In this study we examine this relationship ...

Last Updated: 16 Jan 2014

Go To URL
Structural abnormalities in early Tourette syndrome children: a combined voxel-based morphometry and tract-based spatial statistics study.
 

Author(s): Yue Liu, Wen Miao, Jieqiong Wang, Peiyi Gao, Guangheng Yin, Liping Zhang, Chuankai Lv, Zhiying Ji, Tong Yu, B A Sabel, Huiguang He, Yun Peng

Journal:

 

Tourette Syndrome (TS) is characterized with chronic motor and vocal tics beginning in childhood. Abnormality of both gray (GM) and white matter (WM) has been observed in cortico-striato-thalamo-cortical circuits and sensory-motor cortex of adult TS patient. It is not clear if these ...

Last Updated: 7 Oct 2013

Go To URL
Brain mechanisms for prepulse inhibition in adults with Tourette syndrome: initial findings.
 

Author(s): Nazlee Zebardast, Michael J Crowley, Michael H Bloch, Linda C Mayes, Brent Vander Wyk, James F Leckman, Kevin A Pelphrey, James E Swain

Journal: Psychiatry Res. 2013 Oct;214(1):33-41.

 

Prepulse inhibition (PPI) of the startle reflex is disrupted in a number of developmental neuropsychiatric disorders, including Tourette syndrome (TS). This disruption is hypothesized to reflect abnormalities in sensorimotor gating. We applied whole-brain functional magnetic resonance ...

Last Updated: 2 Sep 2013

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Tourette Syndrome" returned 26 free, full-text review articles on human participants. First 3 results:

The effectiveness of habit reversal therapy in the treatment of Tourette syndrome and other chronic tic disorders: a systematic review.
 

Author(s): Neeladri Dutta, Andrea E Cavanna

Journal: Funct. Neurol.. ;28(1):7-12.

 

Tourette syndrome (TS) is a neurodevelopmental disorder characterized by multiple tics, which can require active intervention. It is recognized that behavioral techniques, especially habit reversal therapy (HRT), can offer an effective alternative or complement to pharmacotherapy ...

Last Updated: 4 Jun 2013

Go To URL
Immune-mediated animal models of Tourette syndrome.
 

Author(s): Mady Hornig, W Ian Lipkin

Journal: Neurosci Biobehav Rev. 2013 Jul;37(6):1120-38.

 

An autoimmune diathesis has been proposed in Tourette syndrome (TS) and related neuropsychiatric disorders such as obsessive-compulsive disorder, attention-deficit/hyperactivity disorder, autism and anorexia nervosa. Environmental triggers including infection and xenobiotics are hypothesized ...

Last Updated: 4 Jun 2013

Go To URL
Clinical assessment of Tourette syndrome and tic disorders.
 

Author(s): Stephanie C Cohen, James F Leckman, Michael H Bloch

Journal: Neurosci Biobehav Rev. 2013 Jul;37(6):997-1007.

 

Tourette syndrome (TS) is a neuropsychiatric disorder involving multiple motor and phonic tics. Tics, which usually begin between the ages of 6 and 8, are sudden, rapid, stereotyped, and apparently purposeless movements or sounds that involve discrete muscle groups. Individuals with ...

Last Updated: 4 Jun 2013

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Tourette Syndrome Deep Brain Stimulation
 

Status: Not yet recruiting

Condition Summary: Tourette Syndrome

 

Last Updated: 13 May 2014

Go to URL
MRI Study of Tic Remission in Tourette Syndrome
 

Status: Recruiting

Condition Summary: Tourette Syndrome

 

Last Updated: 1 Jun 2012

Go to URL
FAAH Inhibitor Trial for Adults With Tourette Syndrome
 

Status: Recruiting

Condition Summary: Tourette Syndrome

 

Last Updated: 29 Jul 2014

Go to URL