Thrombocytopenia 2

Common Name(s)

Thrombocytopenia 2

Thrombocytopenia-2 is an autosomal dominant nonsyndromic disorder characterized by decreased numbers of normal platelets, resulting in a mild bleeding tendency. Laboratory studies show no defects in platelet function or morphology, and bone marrow examination shows normal numbers of megakaryocytes and normal maturation stages, suggesting defective platelet production or release (summary by {18:Pippucci et al., 2011}).
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Thrombocytopenia 2" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Thrombocytopenia 2" returned 9 free, full-text research articles on human participants. First 3 results:

Spontaneous heparin-induced thrombocytopenia syndrome: 2 new cases and a proposal for defining this disorder.
 

Author(s): Theodore E Warkentin, Paul A Basciano, Jared Knopman, Richard A Bernstein

Journal: Blood. 2014 Jun;123(23):3651-4.

 

The existence of spontaneous heparin-induced thrombocytopenia (HIT) syndrome (or autoimmune HIT), defined as a transient prothrombotic thrombocytopenic disorder without proximate heparin exposure serologically indistinguishable from HIT, is controversial. We describe 2 new cases presenting ...

Last Updated: 6 Jun 2014

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Severe thrombocytopenia due to repaglinide in a patient with type 2 diabetes.
 

Author(s): Hisayuki Katsuyama, Chika Hiraishi, Yuki Hakoshima, Hidekatsu Yanai

Journal: Diabetes Care. 2013 Mar;36(3):e36.

 

Last Updated: 22 Feb 2013

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Imbalance of angiopoietin-1 and angiopoetin-2 in severe dengue and relationship with thrombocytopenia, endothelial activation, and vascular stability.
 

Author(s): Meta Michels, André J A M van der Ven, Kis Djamiatun, Rob Fijnheer, Philip G de Groot, Arjan W Griffioen, Silvie Sebastian, Sultana M H Faradz, Quirijn de Mast

Journal: Am. J. Trop. Med. Hyg.. 2012 Nov;87(5):943-6.

 

The pathogenesis of plasma leakage during dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS) is largely unknown. Angiopoietins are key regulators of vascular integrity: Angiopoietin-1 is stored in platelets and maintains vascular integrity, and endothelium-derived angiopoietin-2 ...

Last Updated: 8 Nov 2012

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Reviews from the PubMed Database

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The terms "Thrombocytopenia 2" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Pilot Study of a Thrombopoietin-Receptor Agonist, Eltrombopag, in Patients With Low to Int-2 Risk Myelodysplastic Syndrome (MDS)
 

Status: Recruiting

Condition Summary: Myelodysplastic Syndromes; Thrombocytopenia

 

Last Updated: 10 Apr 2015

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