Thrombocytopenia 2

Common Name(s)

Thrombocytopenia 2

Thrombocytopenia-2 is an autosomal dominant nonsyndromic disorder characterized by decreased numbers of normal platelets, resulting in a mild bleeding tendency. Laboratory studies show no defects in platelet function or morphology, and bone marrow examination shows normal numbers of megakaryocytes and normal maturation stages, suggesting defective platelet production or release (summary by {18:Pippucci et al., 2011}).
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Thrombocytopenia 2" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Thrombocytopenia 2" returned 15 free, full-text research articles on human participants. First 3 results:

A 2-Year, Longitudinal, Prospective Study of the Effects of Eltrombopag on Bone Marrow in Patients with Chronic Immune Thrombocytopenia.
 

Author(s): Russell K Brynes, Raymond S M Wong, Maung M Thein, Kalpana K Bakshi, Paul Burgess, Dickens Theodore, Attilio Orazi

Journal: Acta Haematol.. 2017 ;137(2):66-72.

 

The long-term effects of eltrombopag on bone marrow (BM) reticulin and/or collagen deposition in previously treated adults with chronic immune thrombocytopenia (ITP) were assessed.

Last Updated: 22 Dec 2016

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Linezolid-Induced Thrombocytopenia Is Caused by Suppression of Platelet Production via Phosphorylation of Myosin Light Chain 2.
 

Author(s): Masataka Tajima, Yoshinori Kato, Jun Matsumoto, Iori Hirosawa, Mariko Suzuki, Yuki Takashio, Mao Yamamoto, Yoshifumi Nishi, Harumi Yamada

Journal: Biol. Pharm. Bull.. 2016 ;39(11):1846-1851.

 

Linezolid (LZD) is an antimicrobial that is commonly used for treatment of vancomycin-resistant Enterococci and methicillin-resistant Staphylococcus aureus infections. However, the development of thrombocytopenia, one of the most frequent adverse side effects of this antimicrobial, ...

Last Updated: 2 Nov 2016

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Angiopoietin-2 and angiopoietin-2/angiopoietin-1 ratio as indicators of potential severity of Plasmodium vivax malaria in patients with thrombocytopenia.
 

Author(s): Luciano Teixeira Gomes, Eduardo Rodrigues Alves-Junior, Clebson Rodrigues-Jesus, Andreia Ferreira Nery, Thamires Oliveira Gasquez-Martin, Cor Jesus Fontes

Journal:

 

Angiogenic factors such as angiopoietin 1 (Ang-1) and angiopoietin 2 (Ang-2) are biomarkers produced during activation and dysfunction of the vascular endothelium in several infectious diseases. The aim of this study was to determine the serum levels of Ang-1 and Ang-2 and to establish ...

Last Updated: 3 Oct 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Thrombocytopenia 2" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Pilot Study of a Thrombopoietin-Receptor Agonist, Eltrombopag, in Patients With Low to Int-2 Risk Myelodysplastic Syndrome (MDS)
 

Status: Recruiting

Condition Summary: Myelodysplastic Syndromes; Thrombocytopenia

 

Last Updated: 20 Apr 2017

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Immunogenetics of Heparin-Induced Thrombocytopenia: Aim 2
 

Status: Recruiting

Condition Summary: Heparin-induced Thrombocytopenia

 

Last Updated: 2 May 2016

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A Phase 2 Study to Evaluate the Efficacy and Safety of AMG531 in Aplastic Anemia
 

Status: Recruiting

Condition Summary: Aplastic Anemia

 

Last Updated: 22 Feb 2017

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