Thalassemia

Common Name(s)

Thalassemia

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Thalassemia" for support, advocacy or research.

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Cooleys Anemia Foundation, Inc.

Advancing the treatment and cure for this genetic blood disease. Enhancing the quality of life of patients. Educating the medical profession, thalassemia trait carriers and the public about thalassemia.

http://cooleysanemia.org

Last Updated: 11 Feb 2013

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werathah

To provide support and health education to patients and their families with genetic and congenital disorders

http://www.werathah.com

Last Updated: 1 May 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Thalassemia" for support, advocacy or research.

Logo
Cooleys Anemia Foundation, Inc.

Advancing the treatment and cure for this genetic blood disease. Enhancing the quality of life of patients. Educating the medical profession, thalassemia trait carriers and the public about thalassemia.

http://cooleysanemia.org

Last Updated: 11 Feb 2013

View Details
werathah

To provide support and health education to patients and their families with genetic and congenital disorders

http://www.werathah.com

Last Updated: 1 May 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Thalassemia" returned 1073 free, full-text research articles on human participants. First 3 results:

Interaction of hemoglobin Grey Lynn (Vientiane) with a non-deletional α(+)-thalassemia in an adult Thai proband.
 

Author(s): Kritsada Singha, Goonnapa Fucharoen, Supan Fucharoen

Journal:

 

Hemoglobin (Hb) Grey Lynn is a Hb variant caused by a substitution of Phe for Leu at position 91 of α1-globin chain, originally described in individual of unknown ethnic background. This article addresses the interaction of Hb Grey Lynn with a non-deletional α(+)-thalassemia found ...

Last Updated: 14 Mar 2014

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Updates of the HbVar database of human hemoglobin variants and thalassemia mutations.
 

Author(s): Belinda Giardine, Joseph Borg, Emmanouil Viennas, Cristiana Pavlidis, Kamran Moradkhani, Philippe Joly, Marina Bartsakoulia, Cathy Riemer, Webb Miller, Giannis Tzimas, Henri Wajcman, Ross C Hardison, George P Patrinos

Journal: Nucleic Acids Res.. 2014 Jan;42(Database issue):D1063-9.

 

HbVar (http://globin.bx.psu.edu/hbvar) is one of the oldest and most appreciated locus-specific databases launched in 2001 by a multi-center academic effort to provide timely information on the genomic alterations leading to hemoglobin variants and all types of thalassemia and hemoglobinopathies. ...

Last Updated: 30 Dec 2013

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An ironic case of liver infections: Yersinia enterocolitis in the setting of thalassemia.
 

Author(s): Nathan Selsky, Faripour Forouhar, George Y Wu

Journal: World J. Gastroenterol.. 2013 Oct;19(37):6296-8.

 

A 49 years old Vietnamese male with a history of thalassemia, presented with gastrointestinal symptoms and signs of hemolysis. He was diagnosed with yersinia enterocolitis. Yersinia is a gram-negative rod that most frequently occurs in children especially during the winter months. ...

Last Updated: 11 Oct 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Thalassemia" returned 53 free, full-text review articles on human participants. First 3 results:

Ineffective erythropoiesis in β -thalassemia.
 

Author(s): Jean-Antoine Ribeil, Jean-Benoit Arlet, Michael Dussiot, Ivan Cruz Moura, Geneviève Courtois, Olivier Hermine

Journal:

 

In humans, β -thalassemia dyserythropoiesis is characterized by expansion of early erythroid precursors and erythroid progenitors and then ineffective erythropoiesis. This ineffective erythropoiesis is defined as a suboptimal production of mature erythrocytes originating from a proliferating ...

Last Updated: 22 Apr 2013

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Cross-talk between available guidelines for the management of patients with beta-thalassemia major.
 

Author(s): Khaled M Musallam, Michael Angastiniotis, Androulla Eleftheriou, John B Porter

Journal: Acta Haematol.. 2013 ;130(2):64-73.

 

Efforts to optimize the management of patients with β-thalassemia major (TM) continue to expand. Evidence from biomedical research evaluating safe and careful processing measures of blood products, the efficacy and safety of oral iron chelators, and noninvasive techniques for the ...

Last Updated: 30 Aug 2013

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Treating iron overload in patients with non-transfusion-dependent thalassemia.
 

Author(s): Ali T Taher, Vip Viprakasit, Khaled M Musallam, M Domenica Cappellini

Journal: Am. J. Hematol.. 2013 May;88(5):409-15.

 

Despite receiving no or only occasional blood transfusions, patients with non-transfusion-dependent thalassemia (NTDT) have increased intestinal iron absorption and can accumulate iron to levels comparable with transfusion-dependent patients. This iron accumulation occurs more slowly ...

Last Updated: 22 Apr 2013

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study to Determine the Safety and Tolerability of Sotatercept (ACE-011) in Adults With Beta( β)- Thalassemia.
 

Status: Recruiting

Condition Summary: Beta Thalassemia Major; Beta Thalassemia Intermedia

 

Last Updated: 11 Dec 2013

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Beta-thalassemia and Microparticles
 

Status: Recruiting

Condition Summary: Thalassemia Major (TM); Thalassemia Intermedia (TI); Microparticles (MP)Originating From Platelets, Endothelial Cells and Monocytes

 

Last Updated: 26 Jan 2011

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