Stargardt disease 4

Common Name(s)

Stargardt disease 4

Stargardt disease is the most common hereditary macular dystrophy and is characterized by decreased central vision, atrophy of the macula and underlying retinal pigment epithelium, and frequent presence of prominent flecks in the posterior pole of the retina. STGD is most commonly inherited as an autosomal recessive trait (see {248200}), but STGD4 is inherited as an autosomal domiant trait (summary by {1:Kniazeva et al., 1999}).
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Stargardt disease 4" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Stargardt disease 4" returned 2 free, full-text research articles on human participants. First 3 results:

Retinal pathology and skin barrier defect in mice carrying a Stargardt disease-3 mutation in elongase of very long chain fatty acids-4.
 

Author(s): Anne McMahon, Igor A Butovich, Nathan L Mata, Martin Klein, Robert Ritter, James Richardson, David G Birch, Albert O Edwards, Wojciech Kedzierski

Journal:

 

Autosomal dominant Stargardt disease-3 (STGD3) is caused by mutations in elongase of very long chain fatty acids-4 (ELOVL4). The goal of this study was to generate and characterize heterozygous and homozygous knockin-mice that carry a human STGD3 pathogenic mutation in the mouse Elovl4 gene.

Last Updated: 14 Mar 2007

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A new locus for autosomal dominant stargardt-like disease maps to chromosome 4.
 

Author(s): M Kniazeva, M F Chiang, B Morgan, A L Anduze, D J Zack, M Han, K Zhang

Journal: Am. J. Hum. Genet.. 1999 May;64(5):1394-9.

 

Stargardt disease (STGD) is the most common hereditary macular dystrophy and is characterized by decreased central vision, atrophy of the macula and underlying retinal-pigment epithelium, and frequent presence of prominent flecks in the posterior pole of the retina. STGD is most commonly ...

Last Updated: 20 May 1999

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Reviews from the PubMed Database

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The terms "Stargardt disease 4" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 9 May 2014

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A Natural History of the Progression of Stargardt Disease: Retrospective and Prospective Studies
 

Status: Recruiting

Condition Summary: Stargardt Disease

 

Last Updated: 7 Nov 2013

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