Short qt syndrome 1

Common Name(s)

Short qt syndrome 1

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Short qt syndrome 1" for support, advocacy or research.

SADS (Sudden Arrhythmia Death Syndromes) Foundation

Our mission is to save the lives of young people who are genetically predisposed to sudden death due to cardiac arrhythmia and to provide education and support to families and the medical community.

Last Updated: 29 Apr 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Short qt syndrome 1" for support, advocacy or research.

SADS (Sudden Arrhythmia Death Syndromes) Foundation

Our mission is to save the lives of young people who are genetically predisposed to sudden death due to cardiac arrhythmia and to provide education and support to families and the medical community.

http://www.StopSADS.org

Last Updated: 29 Apr 2014

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General Support Organizations

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General Resources

SADS Foundation Website

Information on living with SADS, diagnosis, treatment, prevention, and advocacy/education.

Updated 29 Apr 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Short qt syndrome 1" returned 8 free, full-text research articles on human participants. First 3 results:

Action potential clamp and pharmacology of the variant 1 Short QT Syndrome T618I hERG K⁺ channel.
 

Author(s): Aziza El Harchi, Dario Melgari, Yi Hong Zhang, Henggui Zhang, Jules C Hancox

Journal: PLoS ONE. 2012 ;7(12):e52451.

 

The familial Short QT Syndrome (SQTS) is associated with an increased risk of cardiac arrhythmia and sudden death. Gain-of-function mutations in the hERG K(+) channel protein have been linked to variant 1 of the SQTS. A hERG channel pore (T618I) mutation has recently been identified ...

Last Updated: 9 Jan 2013

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Decreased inward rectification of Kir2.1 channels is a novel mechanism underlying the short QT syndrome.
 

Author(s): Simona Casini, Alex V Postma

Journal: Cardiovasc. Res.. 2012 Mar;93(4):535-6.

 

Last Updated: 2 Mar 2012

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Increased vulnerability of human ventricle to re-entrant excitation in hERG-linked variant 1 short QT syndrome.
 

Author(s): Ismail Adeniran, Mark J McPate, Harry J Witchel, Jules C Hancox, Henggui Zhang

Journal: PLoS Comput. Biol.. 2011 Dec;7(12):e1002313.

 

The short QT syndrome (SQTS) is a genetically heterogeneous condition characterized by abbreviated QT intervals and an increased susceptibility to arrhythmia and sudden death. This simulation study identifies arrhythmogenic mechanisms in the rapid-delayed rectifier K(+) current (I(Kr))-linked ...

Last Updated: 23 Dec 2011

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Short qt syndrome 1" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.