Scoliosis

Common Name(s)

Scoliosis

Scoliosis is a sideways curvature of the spine that usually occurs during a growth spurt before puberty. Scoliosis can range from mild to severe and can cause back pain and difficulty breathing. Indicators of scoliosis are uneven shoulders, waist, and hips. The cause of scoliosis is largly unknown, however it may be hereditary. Scoliosis is less commonly a result of cerebral palsy, birth defects affecting the development of the spine, and injuries or infections of the spine.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Scoliosis" for support, advocacy or research.

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Canadian Marfan Association

Increasing awareness, saving lives, and improving the quality of life for patients, their families, and medical professionals affected by Marfan syndrome, genetic aortic disorders, and related connective tissue disorders through national programs of education, support, and research.

Last Updated: 22 Jan 2013

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Chiari & Syringomyelia Foundation

Our mission is to advance knowledge through research and to educate the medical, allied sciences, and lay community about Chiari malformation, syringomyelia and related CSF (cerebrospinal fluid) disorders.

Last Updated: 18 Mar 2013

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National Scoliosis Foundation

The National Scoliosis Foundation (NSF) is a patient-led nonprofit organization dedicated since 1976 to helping children, parents, adults, and health-care providers to understand the complexities of spinal deformities such as scoliosis.

Last Updated: 24 Nov 2009

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Scoliosis" for support, advocacy or research.

Logo
Canadian Marfan Association

Increasing awareness, saving lives, and improving the quality of life for patients, their families, and medical professionals affected by Marfan syndrome, genetic aortic disorders, and related connective tissue disorders through national programs of education, support, and research.

http://www.marfan.ca

Last Updated: 22 Jan 2013

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Chiari & Syringomyelia Foundation

Our mission is to advance knowledge through research and to educate the medical, allied sciences, and lay community about Chiari malformation, syringomyelia and related CSF (cerebrospinal fluid) disorders.

http://www.CSFinfo.org

Last Updated: 18 Mar 2013

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National Scoliosis Foundation

The National Scoliosis Foundation (NSF) is a patient-led nonprofit organization dedicated since 1976 to helping children, parents, adults, and health-care providers to understand the complexities of spinal deformities such as scoliosis.

http://www.scoliosis.org/

Last Updated: 24 Nov 2009

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Scoliosis" returned 1033 free, full-text research articles on human participants. First 3 results:

Transient Monoplegia as a Result of Unilateral Femoral Artery Ischemia Detected by Multimodal Intraoperative Neuromonitoring in Posterior Scoliosis Surgery: A Case Report.
 

Author(s): Rafal Pankowski, Marek Roclawski, Krzysztof Dziegiel, Marcin Ceynowa, Marcin Mikulicz, Tomasz Mazurek, Wojciech Kloc

Journal: Medicine (Baltimore). 2016 Feb;95(6):e2748.

 

This is to report a case of 16-year-old girl with transient right lower limb monoplegia as a result of femoral artery ischemia detected by multimodal intraoperative spinal cord neuromonitoring (MISNM) during posterior correction surgery of adolescent idiopathic scoliosis.A patient ...

Last Updated: 13 Feb 2016

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Adult Degenerative Scoliosis: Can Cobb Angle on a Supine Posteroanterior Radiograph Be Used to Predict the Cobb Angle in a Standing Position?
 

Author(s): Changwei Yang, Yanming Li, Yunfei Zhao, Xiaodong Zhu, Ming Li, Gabriel Liu

Journal: Medicine (Baltimore). 2016 Feb;95(6):e2732.

 

It is necessary to assess coronal Cobb angle in the diagnosis and treatment of patients with adult degenerative scoliosis (ADS). But as most ADS patients are elderly patients who are difficult or unable to stand upright without assistance, it is difficult to obtain standing posteroanterior ...

Last Updated: 13 Feb 2016

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Functional Investigation of a Non-coding Variant Associated with Adolescent Idiopathic Scoliosis in Zebrafish: Elevated Expression of the Ladybird Homeobox Gene Causes Body Axis Deformation.
 

Author(s): Long Guo, Hiroshi Yamashita, Ikuyo Kou, Aki Takimoto, Makiko Meguro-Horike, Shin-ichi Horike, Tetsushi Sakuma, Shigenori Miura, Taiji Adachi, Takashi Yamamoto, Shiro Ikegawa, Yuji Hiraki, Chisa Shukunami

Journal:

 

Previously, we identified an adolescent idiopathic scoliosis susceptibility locus near human ladybird homeobox 1 (LBX1) and FLJ41350 by a genome-wide association study. Here, we characterized the associated non-coding variant and investigated the function of these genes. A chromosome ...

Last Updated: 29 Jan 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Scoliosis" returned 90 free, full-text review articles on human participants. First 3 results:

[Degenerative adult scoliosis].
 

Author(s): C L García-Ramos, C A Obil-Chavarría, B Zárate-Kalfópulos, L M Rosales-Olivares, A Alpizar-Aguirre, A A Reyes-Sánchez

Journal: Acta Ortop Mex. ;29(2):127-38.

 

Adult scoliosis is a complex three-dimensional rotational deformity of the spine, resulting from the progressive degeneration of the vertebral elements in middle age, in a previously straight spine; a Cobb angle greater than 10° in the coronal plane, which also alters the sagittal ...

Last Updated: 25 Mar 2016

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Thoracolumbar Scoliosis Due to Cryptococcal Osteomyelitis: A Case Report and Review of the Literature.
 

Author(s): Zheng Li, Jinqian Liang, Jianxiong Shen, Guixing Qiu, Xisheng Weng

Journal: Medicine (Baltimore). 2016 Feb;95(5):e2613.

 

Cryptococcus neoformans causes opportunistic infections in immunocompromised patients, with vertebral osteomyelitis being a very rare involvement.This study is to present a case of thoracolumbar scoliosis occurring in the setting of cryptococcal osteomyelitis.Pharmacological intervention ...

Last Updated: 5 Feb 2016

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State of the art of current 3-D scoliosis classifications: a systematic review from a clinical perspective.
 

Author(s): Sabrina Donzelli, Salvatore Poma, Luca Balzarini, Alberto Borboni, Stefano Respizzi, Jorge Hugo Villafane, Fabio Zaina, Stefano Negrini

Journal:

 

Scoliosis is a complex three dimensional (3D) deformity: the current lack of a 3D classification could hide something fundamental for scoliosis prognosis and treatment. A clear picture of the actually existing 3D classifications lacks. The aim of this systematic review was to identify ...

Last Updated: 17 Oct 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Impact of Aerobic Training and Combined in Inflammatory Markers in Patients With Adolescent Idiopathic Scoliosis
 

Status: Recruiting

Condition Summary: Scoliosis; Adolescent Scoliosis

 

Last Updated: 8 Mar 2016

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Robotic vs. Freehand Corrective Surgery for Pediatric Scoliosis
 

Status: Recruiting

Condition Summary: Scoliosis

 

Last Updated: 5 Jan 2016

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Prospective Study of Scoliosis in Children With Cerebral Palsy
 

Status: Recruiting

Condition Summary: Cerebral Palsy; Scoliosis

 

Last Updated: 18 Apr 2016

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