Scoliosis

Common Name(s)

Scoliosis

Scoliosis is a sideways curvature of the spine that usually occurs during a growth spurt before puberty. Scoliosis can range from mild to severe and can cause back pain and difficulty breathing. Indicators of scoliosis are uneven shoulders, waist, and hips. The cause of scoliosis is largly unknown, however it may be hereditary. Scoliosis is less commonly a result of cerebral palsy, birth defects affecting the development of the spine, and injuries or infections of the spine.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Scoliosis" for support, advocacy or research.

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Canadian Marfan Association

Increasing awareness, saving lives, and improving the quality of life for patients, their families, and medical professionals affected by Marfan syndrome, genetic aortic disorders, and related connective tissue disorders through national programs of education, support, and research.

Last Updated: 22 Jan 2013

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Chiari & Syringomyelia Foundation

Our mission is to advance knowledge through research and to educate the medical, allied sciences, and lay community about Chiari malformation, syringomyelia and related CSF (cerebrospinal fluid) disorders.

Last Updated: 18 Mar 2013

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National Scoliosis Foundation

The National Scoliosis Foundation (NSF) is a patient-led nonprofit organization dedicated since 1976 to helping children, parents, adults, and health-care providers to understand the complexities of spinal deformities such as scoliosis.

Last Updated: 24 Nov 2009

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Scoliosis" for support, advocacy or research.

Logo
Canadian Marfan Association

Increasing awareness, saving lives, and improving the quality of life for patients, their families, and medical professionals affected by Marfan syndrome, genetic aortic disorders, and related connective tissue disorders through national programs of education, support, and research.

http://www.marfan.ca

Last Updated: 22 Jan 2013

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Chiari & Syringomyelia Foundation

Our mission is to advance knowledge through research and to educate the medical, allied sciences, and lay community about Chiari malformation, syringomyelia and related CSF (cerebrospinal fluid) disorders.

http://www.CSFinfo.org

Last Updated: 18 Mar 2013

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National Scoliosis Foundation

The National Scoliosis Foundation (NSF) is a patient-led nonprofit organization dedicated since 1976 to helping children, parents, adults, and health-care providers to understand the complexities of spinal deformities such as scoliosis.

http://www.scoliosis.org/

Last Updated: 24 Nov 2009

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Scoliosis" returned 860 free, full-text research articles on human participants. First 3 results:

Factors associated with scoliosis in schoolchildren: a cross-sectional population-based study.
 

Author(s): Marina Pegoraro Baroni, Geronimo José Bouzas Sanchis, Sanderson José Costa de Assis, Rafael Gomes dos Santos, Silvana Alves Pereira, Klayton Galante Sousa, Johnnatas Mikael Lopes

Journal: J Epidemiol. 2015 ;25(3):212-20.

 

The present study aimed to investigate the prevalence of scoliosis and to analyze the factors associated with scoliosis in schoolchildren aged between 7 and 17 years.

Last Updated: 11 Mar 2015

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Functional variants of POC5 identified in patients with idiopathic scoliosis.
 

Author(s): Shunmoogum A Patten, Patricia Margaritte-Jeannin, Jean-Claude Bernard, Eudeline Alix, Audrey Labalme, Alicia Besson, Simon L Girard, Khaled Fendri, Nicolas Fraisse, Bernard Biot, Coline Poizat, Amandine Campan-Fournier, Kariman Abelin-Genevois, Vincent Cunin, Charlotte Zaouter, Meijiang Liao, Raphaelle Lamy, Gaetan Lesca, Rita Menassa, Charles Marcaillou, Melanie Letexier, Damien Sanlaville, Jerome Berard, Guy A Rouleau, Françoise Clerget-Darpoux, Pierre Drapeau, Florina Moldovan, Patrick Edery

Journal: J. Clin. Invest.. 2015 Mar;125(3):1124-8.

 

Idiopathic scoliosis (IS) is a spine deformity that affects approximately 3% of the population. The underlying causes of IS are not well understood, although there is clear evidence that there is a genetic component to the disease. Genetic mapping studies suggest high genetic heterogeneity, ...

Last Updated: 3 Mar 2015

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TBX6 null variants and a common hypomorphic allele in congenital scoliosis.
 

Author(s): N Wu, X Ming, J Xiao, Z Wu, X Chen, M Shinawi, Y Shen, G Yu, J Liu, H Xie, Z S Gucev, S Liu, N Yang, H Al-Kateb, J Chen, J Zhang, N Hauser, T Zhang, V Tasic, P Liu, X Su, X Pan, C Liu, L Wang, J Shen, J Shen, Y Chen, T Zhang, J Zhang, K W Choy, J Wang, Q Wang, S Li, W Zhou, J Guo, Y Wang, C Zhang, Hong Zhao, Yu An, Yu Zhao, J Wang, Z Liu, Y Zuo, Y Tian, X Weng, V R Sutton, H Wang, Y Ming, S Kulkarni, T P Zhong, P F Giampietro, S L Dunwoodie, S W Cheung, X Zhang, L Jin, J R Lupski, G Qiu, F Zhang

Journal: N. Engl. J. Med.. 2015 Jan;372(4):341-50.

 

Congenital scoliosis is a common type of vertebral malformation. Genetic susceptibility has been implicated in congenital scoliosis.

Last Updated: 22 Jan 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Scoliosis" returned 72 free, full-text review articles on human participants. First 3 results:

Non-surgical interventions for adolescents with idiopathic scoliosis: an overview of systematic reviews.
 

Author(s): Maciej Płaszewski, Josette Bettany-Saltikov

Journal:

 

Non-surgical interventions for adolescents with idiopathic scoliosis remain highly controversial. Despite the publication of numerous reviews no explicit methodological evaluation of papers labeled as, or having a layout of, a systematic review, addressing this subject matter, is available.

Last Updated: 30 Oct 2014

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[Perceived self-image in adolescent idiopathic scoliosis: an integrative review of the literature].
 

Author(s): Maria Isabel Bonilla Carrasco, Maria Carmen Solano Ruiz

Journal: Rev Esc Enferm USP. 2014 Aug;48(4):748-58.

 

To learn about the experiences of adolescents diagnosed with idiopathic scoliosis.

Last Updated: 23 Oct 2014

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Congential scoliosis in Wilson's disease: case report and review of the literature.
 

Author(s): Zheng Li, Xin Yu, Jianxiong Shen, Jinqian Liang

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Wilson's disease (WD) is an autosomal recessive disorder of copper metabolism, which leads to the accumulation of this metal in liver, brain, cornea and kidney. Little is reported about spinal deformity associated with this syndrome. This study is to present a case of thoracic kyphosis ...

Last Updated: 29 Sep 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Impact of Aerobic Training and Combined in Inflammatory Markers in Patients With Adolescent Idiopathic Scoliosis
 

Status: Recruiting

Condition Summary: Scoliosis; Adolescent Scoliosis

 

Last Updated: 15 Jun 2015

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Robotic vs. Freehand Corrective Surgery for Pediatric Scoliosis
 

Status: Recruiting

Condition Summary: Scoliosis

 

Last Updated: 22 Jun 2015

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Prospective Study of Scoliosis in Children With Cerebral Palsy
 

Status: Recruiting

Condition Summary: Cerebral Palsy; Scoliosis

 

Last Updated: 20 Dec 2013

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