Scoliosis

Common Name(s)

Scoliosis

Scoliosis is a sideways curvature of the spine that usually occurs during a growth spurt before puberty. Scoliosis can range from mild to severe and can cause back pain and difficulty breathing. Indicators of scoliosis are uneven shoulders, waist, and hips. The cause of scoliosis is largly unknown, however it may be hereditary. Scoliosis is less commonly a result of cerebral palsy, birth defects affecting the development of the spine, and injuries or infections of the spine.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Scoliosis" for support, advocacy or research.

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Canadian Marfan Association

Increasing awareness, saving lives, and improving the quality of life for patients, their families, and medical professionals affected by Marfan syndrome, genetic aortic disorders, and related connective tissue disorders through national programs of education, support, and research.

Last Updated: 22 Jan 2013

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Chiari & Syringomyelia Foundation

Our mission is to advance knowledge through research and to educate the medical, allied sciences, and lay community about Chiari malformation, syringomyelia and related CSF (cerebrospinal fluid) disorders.

Last Updated: 18 Mar 2013

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National Scoliosis Foundation

The National Scoliosis Foundation (NSF) is a patient-led nonprofit organization dedicated since 1976 to helping children, parents, adults, and health-care providers to understand the complexities of spinal deformities such as scoliosis.

Last Updated: 24 Nov 2009

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Scoliosis" for support, advocacy or research.

Logo
Canadian Marfan Association

Increasing awareness, saving lives, and improving the quality of life for patients, their families, and medical professionals affected by Marfan syndrome, genetic aortic disorders, and related connective tissue disorders through national programs of education, support, and research.

http://www.marfan.ca

Last Updated: 22 Jan 2013

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Chiari & Syringomyelia Foundation

Our mission is to advance knowledge through research and to educate the medical, allied sciences, and lay community about Chiari malformation, syringomyelia and related CSF (cerebrospinal fluid) disorders.

http://www.CSFinfo.org

Last Updated: 18 Mar 2013

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National Scoliosis Foundation

The National Scoliosis Foundation (NSF) is a patient-led nonprofit organization dedicated since 1976 to helping children, parents, adults, and health-care providers to understand the complexities of spinal deformities such as scoliosis.

http://www.scoliosis.org/

Last Updated: 24 Nov 2009

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Scoliosis" returned 990 free, full-text research articles on human participants. First 3 results:

Effect of a Traditional Chinese Medicine combined therapy on adolescent idiopathic scoliosis: a randomized controlled trial.
 

Author(s): Hui Wei, Jinyuan Xu, Zhong Jiang, Shuliang Ye, Hongquan Song, Xitao Ning, Huanmin Huang, Wei Chen, Jianwei Pei, Nengyi Jiang, Shao Chen, Honggen Du

Journal: J Tradit Chin Med. 2015 Oct;35(5):514-9.

 

To evaluate the effectiveness of a combined Traditional Chinese Medicine (TCM) therapy versus conventional treatment on adolescent idiopathic scoliosis.

Last Updated: 20 Nov 2015

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Chinese Adaptation of the Bad Sobernheim Stress Questionnaire for Patients With Adolescent Idiopathic Scoliosis Under Brace Treatment.
 

Author(s): Ximing Xu, Fei Wang, Mingyuan Yang, Qikai Huang, Yifan Chang, Xianzhao Wei, Yushu Bai, Ming Li

Journal: Medicine (Baltimore). 2015 Aug;94(31):e1236.

 

Bad Sobernheim Stress Questionnaire (BSSQ)-Deformity and BSSQ-Brace are the most widely used instruments for evaluating stress levels in adolescent idiopathic scoliosis (AIS) patients under brace treatment, and good reliability and validity have been demonstrated across different ...

Last Updated: 8 Aug 2015

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A Functional SNP in BNC2 Is Associated with Adolescent Idiopathic Scoliosis.
 

Author(s): Yoji Ogura, Ikuyo Kou, Shigenori Miura, Atsushi Takahashi, Leilei Xu, Kazuki Takeda, Yohei Takahashi, Katsuki Kono, Noriaki Kawakami, Koki Uno, Manabu Ito, Shohei Minami, Ikuho Yonezawa, Haruhisa Yanagida, Hiroshi Taneichi, Zezhang Zhu, Taichi Tsuji, Teppei Suzuki, Hideki Sudo, Toshiaki Kotani, Kota Watanabe, Naobumi Hosogane, Eijiro Okada, Aritoshi Iida, Masahiro Nakajima, Akihiro Sudo, Kazuhiro Chiba, Yuji Hiraki, Yoshiaki Toyama, Yong Qiu, Chisa Shukunami, Yoichiro Kamatani, Michiaki Kubo, Morio Matsumoto, Shiro Ikegawa

Journal: Am. J. Hum. Genet.. 2015 Aug;97(2):337-42.

 

Adolescent idiopathic scoliosis (AIS) is the most common spinal deformity. We previously conducted a genome-wide association study (GWAS) and detected two loci associated with AIS. To identify additional loci, we extended our GWAS by increasing the number of cohorts (2,109 affected ...

Last Updated: 8 Aug 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Scoliosis" returned 83 free, full-text review articles on human participants. First 3 results:

Congenital scoliosis in Smith-Magenis syndrome: a case report and review of the literature.
 

Author(s): Zheng Li, Jianxiong Shen, Jinqian Liang, Lin Sheng

Journal: Medicine (Baltimore). 2015 May;94(17):e705.

 

The Smith-Magenis syndrome (SMS) is a complex and rare congenital condition that is characterized by minor craniofacial anomalies, short stature, sleep disturbances, behavioral, and neurocognitive abnormalities, as well as variable multisystemic manifestations. Little is reported ...

Last Updated: 1 May 2015

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Scoliosis in mitochondrial myopathy: case report and review of the literature.
 

Author(s): Zheng Li, Jianxiong Shen, Jinqian Liang

Journal: Medicine (Baltimore). 2015 Feb;94(6):e513.

 

The mitochondrial myopathies include a diverse group of disorders characterized by morphological abnormalities of muscle mitochondria. Little is reported about spinal deformity associated with this syndrome.This study presents a case of scoliosis occurring in the setting of mitochondrial ...

Last Updated: 14 Feb 2015

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Early-onset scoliosis: current treatment.
 

Author(s): V Cunin

Journal: Orthop Traumatol Surg Res. 2015 Feb;101(1 Suppl):S109-18.

 

Early-onset scoliosis, which appears before the age of 10, can be due to congenital vertebral anomalies, neuromuscular diseases, scoliosis-associated syndromes, or idiopathic causes. It can have serious consequences for lung development and significantly reduce the life expectancy ...

Last Updated: 10 Feb 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Impact of Aerobic Training and Combined in Inflammatory Markers in Patients With Adolescent Idiopathic Scoliosis
 

Status: Recruiting

Condition Summary: Scoliosis; Adolescent Scoliosis

 

Last Updated: 28 Jan 2016

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Robotic vs. Freehand Corrective Surgery for Pediatric Scoliosis
 

Status: Recruiting

Condition Summary: Scoliosis

 

Last Updated: 5 Jan 2016

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Prospective Study of Scoliosis in Children With Cerebral Palsy
 

Status: Recruiting

Condition Summary: Cerebral Palsy; Scoliosis

 

Last Updated: 20 Dec 2013

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