Retinoblastoma
Common Name(s)
Retinoblastoma
Advocacy and Support Organizations
Condition Specific Organizations
Following organizations serve the condition "Retinoblastoma" for support, advocacy or research.
The Childhood Eye Cancer Trust (CHECT) is dedicated to providing support to families affected by Retinoblastoma (Rb), funding research and raising awareness.
http://www.chect.org.uk
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Advocacy and Support Organizations
Condition Specific Organizations
Following organizations serve the condition "Retinoblastoma" for support, advocacy or research.
The Childhood Eye Cancer Trust (CHECT) is dedicated to providing support to families affected by Retinoblastoma (Rb), funding research and raising awareness.
http://www.chect.org.ukRecommended Apps
Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.
Finding the right clinical trial for Retinoblastoma can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.
Scientific Literature
Articles from the PubMed Database
Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Retinoblastoma" returned 1256 free, full-text research articles on human participants.
First 3 results:
Journal: J. Clin. Invest.. 2014 Jan;124(1):338-52.
Pancreatic ductal adenocarcinoma (PDAC) is often associated with overexpression of TGF-β. Given its tumor suppressor functions, it is unclear whether TGF-β is a valid therapeutic target for PDAC. Here, we found that proliferating pancreatic cancer cells (PCCs) from human PDAC patients ...
Journal: J. Clin. Invest.. 2013 Dec;123(12):5152-64.
The retinoblastoma 1 (RB1) tumor suppressor is a critical regulator of cell cycle progression and development. To investigate the role of RB1 in neural crest-derived melanocytes, we bred mice with a floxed Rb1 allele with mice expressing Cre from the tyrosinase (Tyr) promoter. TyrCre+;Rb1fl/fl ...
Journal: Arq Bras Oftalmol. ;76(4):247-9.
We describe the case of a 9-month old boy with unilateral retinoblastoma and bulftalmo. Primary enucleation was the treatment of choice due to the lack of visual prognosis. The histology of the enucleated eye showed massive choroidal invasion by the tumor and the optic nerve free ...
To view other free, full-text articles on human participants, please click on the link below.
Reviews from the PubMed Database
Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Retinoblastoma" returned 53 free, full-text review articles on human participants.
First 3 results:
Journal: Trends Biochem. Sci.. 2013 Jan;38(1):12-9.
Multisite phosphorylation modulates the function of regulatory proteins with complex signaling properties and outputs. The retinoblastoma tumor suppressor protein (Rb) is inactivated by cyclin-dependent kinase (Cdk) phosphorylation in normal and cancer cell cycles, so understanding ...
Journal: Biochim. Biophys. Acta. ;1829(3-4):385-92.
The retinoblastoma (RB) tumor suppressor protein regulates multiple pathways that influence cell growth, and as a key regulatory node, its function is inactivated in most cancer cells. In addition to its canonical roles in cell cycle control, RB functions as a global repressor of ...
Journal: Eye (Lond). 2013 Feb;27(2):253-64.
In this report, we explore retinoblastoma diagnostic accuracy and review chemotherapy alternatives for retinoblastoma using intravenous, intra-arterial, periocular, and intravitreal routes. A review of 2775 patients referred for management of retinoblastoma, disclosed 78% with confirmed ...
To view other free, full-text review articles on human participants, please click on the link below.
Symptoms, Diagnosis, and Treatment
Clinical Trial Information This information is provided by ClinicalTrials.gov
Condition Summary: Advanced Intra-Ocular Retinoblastoma; Retinoblastoma
Finding the right clinical trial for Retinoblastoma can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.