Renal dysplasia

Common Name(s)

Renal dysplasia

Autosomal recessive renal tubular dysgenesis is a severe disorder of renal tubular development characterized by persistent fetal anuria and perinatal death, probably due to pulmonary hypoplasia from early-onset oligohydramnios (the Potter phenotype) ({5:Gribouval et al., 2005}). Absence or paucity of differentiated proximal tubules is the histopathologic hallmark of the disorder and may be associated with skull ossification defects.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Renal dysplasia" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Renal dysplasia" returned 72 free, full-text research articles on human participants. First 3 results:

A normotensive patient with fibromuscular dysplasia presenting as unilateral renal infarction.
 

Author(s): Gadi Shlomai, Ana Belkin, Orly Goitein, Orith Portnoy, Ehud Grossman

Journal: Isr. Med. Assoc. J.. 2013 May;15(5):258-9.

 

Last Updated: 11 Jul 2013

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Treatment for renovascular hypertension due to fibromuscular dysplasia of renal arteries with renal autotransplantation.
 

Author(s): Leónidas Cruzado-Vega, Julio Hernández-Jaras, Leonor Martín-Abad, Manuel Alonso-Gorrea, Manuel Miralles-Hernández

Journal: Nefrologia. 2013 ;33(2):283-4.

 

Last Updated: 20 Mar 2013

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Double homozygous missense mutations in DACH1 and BMP4 in a patient with bilateral cystic renal dysplasia.
 

Author(s): Raphael Schild, Tanja Knüppel, Martin Konrad, Carsten Bergmann, Agnes Trautmann, Markus J Kemper, Kongming Wu, Sergey Yaklichkin, Jing Wang, Richard Pestell, Dirk E Müller-Wiefel, Franz Schaefer, Stefanie Weber

Journal: Nephrol. Dial. Transplant.. 2013 Jan;28(1):227-32.

 

Renal hypodysplasia (RHD) is characterized by small and/or disorganized kidneys following abnormal organogenesis. Mutations in several genes have been identified recently to be associated with RHD in humans, including BMP4, a member of the transforming growth factor (TGF)-β family ...

Last Updated: 9 Jan 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Renal dysplasia" returned 6 free, full-text review articles on human participants. First 3 results:

Efficacy of revascularization for renal artery stenosis caused by fibromuscular dysplasia: a systematic review and meta-analysis.
 

Author(s): Ludovic Trinquart, Claire Mounier-Vehier, Marc Sapoval, Nathalie Gagnon, Pierre-François Plouin

Journal: Hypertension. 2010 Sep;56(3):525-32.

 

In patients with fibromuscular dysplasia and renal artery stenosis, renal artery revascularization has been used to cure hypertension or to improve blood pressure control. To provide an up-to-date assessment of the benefits and risks associated with revascularization in this condition, ...

Last Updated: 19 Aug 2010

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Genetic approaches to human renal agenesis/hypoplasia and dysplasia.
 

Author(s): Simone Sanna-Cherchi, Gianluca Caridi, Patricia L Weng, Francesco Scolari, Francesco Perfumo, Ali G Gharavi, Gian Marco Ghiggeri

Journal: Pediatr. Nephrol.. 2007 Oct;22(10):1675-84.

 

Congenital abnormalities of the kidney and urinary tract are frequently observed in children and represent a significant cause of morbidity and mortality. These conditions are phenotypically variable, often affecting several segments of the urinary tract simultaneously, making clinical ...

Last Updated: 27 Aug 2007

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Evolving concepts in human renal dysplasia.
 

Author(s): Adrian S Woolf, Karen L Price, Peter J Scambler, Paul J D Winyard

Journal: J. Am. Soc. Nephrol.. 2004 Apr;15(4):998-1007.

 

Human renal dysplasia is a collection of disorders in which kidneys begin to form but then fail to differentiate into normal nephrons and collecting ducts. Dysplasia is the principal cause of childhood end-stage renal failure. Two main theories have been considered in its pathogenesis: ...

Last Updated: 22 Mar 2004

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Ambulatory Blood Pressure Measurement in Children With Congenital Urine Flow Obstruction
 

Status: Available

Condition Summary: Hydronephrosis; Multicystic-Dysplastic Kidney

 

Last Updated: 1 Oct 2008

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Assessing Immune Function in Young Patients With Cytopenia That Did Not Respond to Treatment
 

Status: Recruiting

Condition Summary: Dyskeratosis Congenita; Fanconi Anemia; Myelodysplastic Syndromes; Nonmalignant Neoplasm; Pearson Marrow-pancreas Syndrome; Shwachman-diamond Syndrome

 

Last Updated: 1 Dec 2011

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