Psoriatic arthritis

Common Name(s)

Psoriatic arthritis

Psoriatic arthritis is joint inflammation and stiffness (arthritis) that affects people who have a condition that causes red, itchy, and scaly skin patches (psoriasis). Signs and symptoms of psoriatic arthritis are similar to other forms of arthritis and include stiff and painful joints. In addition, psoriatic arthritis can also cause finger and toe swelling, foot pain and lower back pain. Typically, psoriasis appears before joint problems. Psoriasis symptoms typically occur between the ages of 15 and 35 years and arthritis symptoms usually occur between the ages of 30 and 50. However, both conditions can occur at any age.

Psoriatic arthritis occurs when the body’s immune system attacks healthy cells and tissues. This abnormal immune response, which causes inflammation in your joints, may be due to a combination of genetic and environmental reasons. Risk factors for psoriatic arthritis include having psoriasis, being between the ages of 30 and 50, and having a family history of psoriatic arthritis. There are five types of psoriatic arthritis: distal interphalangeal (DIP), asymmetric oligoarticular, symmetric polyarthritis, spondylitis, and arthritis mutilans. The distal interphalangeal type predominantly affects the ends of fingers and toes. The symmetric polyarthritis form affects matching joints on opposite sides of the body (e.g. Right and left wrist), while the asymmetric oligoarticular type involves nonmatching joints of each side of the body. Spondylitis is inflammation in the joints between the vertebrae in the spine. Arthritis mutilans, which is the most severe and least common type of psoriatic arthritis, causes damage and loss of function of affected joints.

Your doctor may use a physical exam along with imaging and lab tests to diagnosis psoriatic arthritis. There is no cure, but treatment can help manage pain. Talk with a doctor if you have been diagnosed with psoriatic arthritis to discuss the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Psoriatic arthritis" for support, advocacy or research.

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Ben's Friends

Our mission is to ensure that everyone in the world with a rare disease has a safe place to go and connect with others like them.

Last Updated: 11 Jul 2016

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International Foundation for Autoimmune Arthritis

We are committed to eliminating the adversity caused by autoimmune arthritis by uniting resources that will raise global awareness, providing wellness education and support, and conducting patient-centered research that will improve the quality of life for those affected by these diseases.

Last Updated: 18 Sep 2014

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National Psoriasis Foundation

Our mission is to find a cure for psoriasis and psoriatic arthritis and to eliminate their devastating effects through research, advocacy and education.

Last Updated: 26 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Psoriatic arthritis" for support, advocacy or research.

Logo
Ben's Friends

Our mission is to ensure that everyone in the world with a rare disease has a safe place to go and connect with others like them.

http://www.bensfriends.org

Last Updated: 11 Jul 2016

View Details
Logo
International Foundation for Autoimmune Arthritis

We are committed to eliminating the adversity caused by autoimmune arthritis by uniting resources that will raise global awareness, providing wellness education and support, and conducting patient-centered research that will improve the quality of life for those affected by these diseases.

http://www.ifautoimmunearthritis.org

Last Updated: 18 Sep 2014

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National Psoriasis Foundation

Our mission is to find a cure for psoriasis and psoriatic arthritis and to eliminate their devastating effects through research, advocacy and education.

http://www.psoriasis.org/

Last Updated: 26 Jul 2015

View Details

 

General Support Organizations

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General Resources

For scientists and medical professionals

Information about how to apply for National Psoriasis Foundation research grants and fellowships, our medical journal and other science-related materials for medical professionals.

Updated 15 Nov 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Psoriatic arthritis" returned 559 free, full-text research articles on human participants. First 3 results:

The effect of marine n-3 polyunsaturated fatty acids on cardiac autonomic and hemodynamic function in patients with psoriatic arthritis: a randomised, double-blind, placebo-controlled trial.
 

Author(s): Salome Kristensen, Erik Berg Schmidt, Annette Schlemmer, Claus Rasmussen, Esther Lindgreen, Martin Berg Johansen, Jeppe Hagstrup Christensen

Journal:

 

The aim of this study was to investigate the effect of marine n-3 polyunsaturated fatty acids (PUFA) on cardiac autonomic function and vascular function in patients with psoriatic arthritis.

Last Updated: 13 Dec 2016

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A discrete choice experiment to explore patients' willingness to risk disease relapse from treatment withdrawal in psoriatic arthritis.
 

Author(s): Claire Rothery, Laura Bojke, Gerry Richardson, Chris Bojke, Anna Moverley, Laura Coates, Liz Thorp, Robin Waxman, Philip Helliwell

Journal: Clin. Rheumatol.. 2016 Dec;35(12):2967-2974.

 

The objective of this study is to assess patient preferences for treatment-related benefits and risk of disease relapse in the management of low disease states of psoriatic arthritis (PsA). Focus groups with patients and a literature review were undertaken to determine the characteristics ...

Last Updated: 31 Oct 2016

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Serum Interleukin-18, Fetuin-A, Soluble Intercellular Adhesion Molecule-1, and Endothelin-1 in Ankylosing Spondylitis, Psoriatic Arthritis, and SAPHO Syndrome.
 

Author(s): Hanna Przepiera-Będzak, Katarzyna Fischer, Marek Brzosko

Journal:

 

To examine serum interleukin 18 (IL-18), fetuin-A, soluble intercellular adhesion molecule-1 (sICAM-1), and endothelin-1 (ET-1) levels in ankylosing spondylitis (AS), psoriatic arthritis (PsA), and Synovitis Acne Pustulosis Hyperostosis Osteitis syndrome (SAPHO). We studied 81 AS, ...

Last Updated: 16 Aug 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Psoriatic arthritis" returned 118 free, full-text review articles on human participants. First 3 results:

Psoriatic arthritis in Japan: difference in clinical features and approach to precision medicine.
 

Author(s): Yoshiya Tanaka

Journal: Clin. Exp. Rheumatol.. ;34(4 Suppl 98):49-52.

 

Psoriatic arthritis (PsA) is a chronic and progressive inflammatory arthritis that is common among patients with psoriasis, often resulting in permanent damage of joints and spines. Recent report indicates that the prevalence of PsA among Japanese patients with psoriasis is 14.3%, ...

Last Updated: 2 Sep 2016

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Psoriatic arthritis: embracing pathogenetic and clinical heterogeneity?
 

Author(s): Iain B McInnes

Journal: Clin. Exp. Rheumatol.. ;34(4 Suppl 98):9-11.

 

Psoriatic arthritis (PsA) is a clinically heterogeneous condition of skin, joint, enthesis and bone that provides considerable unmet therapeutic need. Recent treatment advances have offered new opportunities to improve quality of life and long term well being for afflicted patients. ...

Last Updated: 2 Sep 2016

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Sex Differences in the Treatment of Psoriatic Arthritis: A Systematic Literature Review.
 

Author(s): Elena Generali, Carlo A Sciré, Luca Cantarini, Carlo Selmi

Journal: Isr. Med. Assoc. J.. ;18(3-4):203-8.

 

Psoriatic arthritis (PsA) is a chronic inflammatory condition associated with skin psoriasis and manifests a wide clinical phenotype, with proposed differences between sexes. Current treatments are based on traditional disease-modifying anti-rheumatic drugs (DMARD), and biologic agents ...

Last Updated: 27 May 2016

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 7 Apr 2017

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