Progressive myositis ossificans

Common Name(s)

Progressive myositis ossificans

Fibrodysplasia ossificans progressiva is a rare autosomal dominant disease with complete penetrance involving progressive ossification of skeletal muscle, fascia, tendons, and ligaments. FOP has a prevalence of approximately 1 in 2 million worldwide, and shows no geographic, ethnic, racial, or gender preference. Individuals with FOP appear normal at birth except for great toe abnormalities: the great toes are short, deviated, and monophalangic. Ossification occurs progressively over the course of a lifetime in an inevitable and unpredictable episodic manner, with most patients being confined to a wheelchair by the third decade of life and requiring lifelong care (summary by {33:Petrie et al., 2009}).
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Progressive myositis ossificans" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Progressive myositis ossificans" returned 1 free, full-text research articles on human participants. First 3 results:

[Progressive myositis ossificans. Stone man].
 

Author(s): J E Fonseca, T Evangelista, L Barroso, J Reis, A R Gomes

Journal: Acta Med Port. ;14(4):429-33.

 

Myositis ossificans progressiva (MOP) is a rare hereditary connective tissue disease, genetically inherited as an autossomal dominant trait with complete penetrance but variable expression. The onset usually takes place during childhood and progressive involvement of the spinal cord ...

Last Updated: 12 Dec 2001

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Reviews from the PubMed Database

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The terms "Progressive myositis ossificans" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

An Efficacy and Safety Study of Palovarotene to Treat Preosseous Flare-ups in FOP Subjects
 

Status: Recruiting

Condition Summary: Fibrodysplasia Ossificans Progressiva

 

Last Updated: 12 Aug 2014

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Urine Sample Collection From FOP Patients
 

Status: Recruiting

Condition Summary: Fibrodysplasia Ossificans Progressiva

 

Last Updated: 27 May 2014

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