Pityriasis rubra pilaris

Common Name(s)

Pityriasis rubra pilaris

Pityriasis rubra pilaris is a skin disorder that causes constant inflammation and scaling (exfoliation) of the skin. Pityriasis rubra pilaris can be divided into 5 categories: classic adult type, atypical adult type, classic juvenile type, circumscribed juvenile type, and atypical juvenile type. More recently, an HIV-associated type has been added to this classification system.  This condition can be inherited or acquired. Pityriasis rubra pilaris may occur at any age, with the familial type commonly starting in early childhood and the acquired type in the fifth or sixth decades of life. Both men and women are affected equally.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pityriasis rubra pilaris" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pityriasis rubra pilaris" returned 21 free, full-text research articles on human participants. First 3 results:

Pityriasis rubra pilaris.
 

Author(s): Marie Leger, Tracey Newlove, Maria Robinson, Rishi Patel, Shane Meehan, Sarika Ramachandran

Journal:

 

Pityriasis rubra pilaris (PRP) is an inflammatory condition of uncertain etiology. We present a case of PRP that demonstrates acantholysis on histopathologic examination, which is a characteristic feature that increasingly is recognized to aid in the diagnosis. We also review the ...

Last Updated: 4 Jan 2013

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Familial pityriasis rubra pilaris is caused by mutations in CARD14.
 

Author(s): Dana Fuchs-Telem, Ofer Sarig, Maurice A M van Steensel, Ofer Isakov, Shirli Israeli, Janna Nousbeck, Katharina Richard, Veronique Winnepenninckx, Marigje Vernooij, Noam Shomron, Jouni Uitto, Philip Fleckman, Gabriele Richard, Eli Sprecher

Journal: Am. J. Hum. Genet.. 2012 Jul;91(1):163-70.

 

Pityriasis rubra pilaris (PRP) is a papulosquamous disorder phenotypically related to psoriasis. The disease has been occasionally shown to be inherited in an autosomal-dominant fashion. To identify the genetic cause of familial PRP, we ascertained four unrelated families affected ...

Last Updated: 16 Jul 2012

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Etanercept-induced clinical remission of type II pityriasis rubra pilaris with rheumatoid arthritis.
 

Author(s): Jong Hoon Kim, Min-Chan Park, Soo-Chan Kim

Journal: Acta Derm. Venereol.. 2012 Jul;92(4):399-400.

 

Last Updated: 6 Aug 2012

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pityriasis rubra pilaris" returned 2 free, full-text review articles on human participants. First 3 results:

Arthritis associated with pityriasis rubra pilaris.
 

Author(s): Paul Y Liu, Pamela E Prete

Journal:

 

Pityriasis rubra pilaris (PRP) is a rare papulosquamous disease of unknown aetiology, with an estimated prevalence of 2.5 per million.1 It is clinically characterised by the presence of follicular hyperkeratotic papules, but the histopathology is usually non-specific. An interesting ...

Last Updated: 6 Jul 2012

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Adult onset pityriasis rubra pilaris.
 

Author(s): Virendra N Sehgal, Govind Srivastava, Sunil Dogra

Journal: Indian J Dermatol Venereol Leprol. ;74(4):311-21.

 

Pityriasis rubra pilaris (PRP) has always been an intriguing topic ever since its inception. It is a group of chronic disorders characterized by reddish orange plaques with pityriasiform scaling showing follicular keratoses, palmoplantar keratoderma, and sometimes, erythroderma. It ...

Last Updated: 17 Sep 2008

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.