Pilomatrixoma

Common Name(s)

Pilomatrixoma

Pilomatrixoma is a benign (non-cancerous) skin tumor of the hair follicle (structure in the skin that makes hair). They tend to develop in the head and neck area and are usually not associated with any other signs and symptoms (isolated). Rarely, pilomatrixomas can become cancerous (known as a pilomatrix carcinoma). Although they can occur in people of all ages, pilomatrixomas are most commonly diagnosed in people under age 20. The exact underlying cause is not well understood; however, somatic changes (mutations) in the CTNNB1 gene are found in most isolated pilomatrixomas. Rarely, pilomatrixomas occur in people with certain genetic syndromes such as Gardner syndrome, myotonic dystrophy, and Rubinstein-Taybi syndrome; in these cases, affected people usually have other characteristic signs and symptoms of the associated condition. They are usually treated with surgical excision.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pilomatrixoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pilomatrixoma" returned 18 free, full-text research articles on human participants. First 3 results:

FDG-PET positive pilomatrixoma--reconsidering multicentricity in Langerhans cell histiocytosis.
 

Author(s): Petr Szturz, Zdeněk Rehák, Renata Koukalová, Zdeněk Adam, Jiří Mayer

Journal: Nucl Med Rev Cent East Eur. 2014 ;17(2):94-6.

 

We report a case of a woman who underwent a curative resection of an upper jaw tumor histologically verified as eosinophilic granuloma. To exclude possible multiorgan involvement, PET/CT imaging was performed and revealed a metabolically active, partially calcified lesion located ...

Last Updated: 4 Aug 2014

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Pilomatrixoma of the breast, a rare lesion simulating breast cancer: a case report.
 

Author(s): Jacopo Nori, Dalmar Abdulcadir, Elisabetta Giannotti, Massimo Calabrese

Journal:

 

Pilomatrixoma or calcifying epithelioma of Malherbe is a rare, benign, skin tumour originating from piliferous follicles; breast localization is considered to be very rare. These lesions can origin from the peri-areolar piliferous bulbs and, due to the clinical and imaging features, ...

Last Updated: 14 Jan 2014

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[Giant pilomatrixoma: a benign tumour with a rare presentation].
 

Author(s): B de Unamuno, R Ballester, P Hernández, I Febrer, V Alegre

Journal: An Pediatr (Barc). 2014 Feb;80(2):e35-6.

 

Last Updated: 31 Jan 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pilomatrixoma" returned 1 free, full-text review articles on human participants. First 3 results:

Pilomatrixoma of the forearm: a case report.
 

Author(s): Michael V Birman, Jonathan B McHugh, Radford J Hayden, Peter J L Jebson

Journal: Iowa Orthop J. 2009 ;29():121-3.

 

Pilomatrixoma is a benign neoplasm derived from hair follicle matrix cells. Involvement of the upper extremities is relatively uncommon and can be mistaken for malignancy. We present the case of a 52-year-old woman with a pilomatrixoma of the forearm, and we review the literature ...

Last Updated: 10 Sep 2009

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Use of Otoscope as a Non-Invasive Tool for Diagnosis of Pilomatricoma
 

Status: Recruiting

Condition Summary: Pilomatrixoma

 

Last Updated: 17 Feb 2009

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Clinical Trial Comparing Tissue Adhesive Vs. Absorbable Suture Vs. Non-Absorbable Suture
 

Status: Recruiting

Condition Summary: Cyst of Face, Neck or Shoulder; Pilomatrixoma of Face, Neck or Shoulder

 

Last Updated: 15 Feb 2006

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