Peeling skin syndrome

Common Name(s)

Peeling skin syndrome

Peeling skin syndrome is a genetic disorder characterized by continual peeling of the skin. Affected individuals may also experience itching and reddening of the skin. The signs and symptoms of peeling skin syndrome usually appear soon after birth, but they may also develop later in life. There are two main subtypes of this condition, called noninflammatory type A and inflammatory type B. In some families, an acral form of peeling skin syndrome has been reported, in which skin peeling is strictly limited to the hands and feet. Peeling skin syndrome has an autosomal recessive pattern of inheritance. Mutations in the TGM5 gene have been identified in several patients with the acral form of peeling skin syndrome.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Peeling skin syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Peeling skin syndrome" returned 11 free, full-text research articles on human participants. First 3 results:

Peeling skin syndrome in eight cases of four different families from India and Bangladesh.
 

Author(s): Nilendu Sarma, Anup Kumar Boler, Dulal Chandra Bhanja

Journal: Indian J Dermatol Venereol Leprol. ;78(5):625-31.

 

Peeling skin syndrome (PSS) is a rare recessively inherited ichthyosiform genodermatoses characterized by superficial skin peeling. This has 2 subtypes, acral (APSS; OMIM 609796) and generalized form (OMIM 270300). The later has been subdivided into type A (non-inflammatory) and type ...

Last Updated: 10 Sep 2012

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TGM5 mutations impact epidermal differentiation in acral peeling skin syndrome.
 

Author(s): Manuela Pigors, Dimitra Kiritsi, Cristina Cobzaru, Agnes Schwieger-Briel, Jose Suárez, Flavio Faletra, Heikki Aho, Leeni Mäkelä, Johannes S Kern, Leena Bruckner-Tuderman, Cristina Has

Journal: J. Invest. Dermatol.. 2012 Oct;132(10):2422-9.

 

Acral peeling skin syndrome (APSS) is an autosomal recessive skin disorder characterized by acral blistering and peeling of the outermost layers of the epidermis. It is caused by mutations in the gene for transglutaminase 5, TGM5. Here, we report on clinical and molecular findings ...

Last Updated: 19 Sep 2012

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Acral peeling skin syndrome in two East-African siblings: case report.
 

Author(s): Samson K Kiprono, Baraka M Chaula, Bernard Naafs, John E Masenga

Journal:

 

Acral peeling skin syndrome is a rare autosomal recessive genodermatosis due to a missense mutation in transglutaminase 5. The skin peeling occurs at the separation of the stratum corneum from the stratum granulosum.

Last Updated: 2 May 2012

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Peeling skin syndrome" returned 1 free, full-text review articles on human participants. First 3 results:

Generalized peeling skin syndrome: Case report and review of the literature.
 

Author(s): Monia Kharfi, Aida Khaled, Donia Ammar, Nadia Ezzine, Nadia El Fekih, Becima Fazaa, Hiabib Jaafoura, Mohamed Ridha Kamoun

Journal:

 

Peeling skin syndrome (PSS) is a rare form of ichthyosis with a probable autosomal recessive inheritance that exhibits superficial, painless, continual, or seasonal cutaneous exfoliation. The syndrome generally appears at birth or in infancy. We report a case of generalized PSS and ...

Last Updated: 17 Mar 2010

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Imaging Lens Deposits in Exfoliation Syndrome
 

Status: Recruiting

Condition Summary: Exfoliation Syndrome; Primary Open Angle Glaucoma; Cataracts

 

Last Updated: 12 Aug 2014

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Last Updated: 3 Sep 2013

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Comparison of Different Surgical Treatments for Different Scales of Cubital Tunnel Syndrome
 

Status: Recruiting

Condition Summary: Cubital Tunnel Syndrome

 

Last Updated: 5 Jul 2013

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