Parkinson disease 2

Common Name(s)

Parkinson disease 2

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Parkinson disease 2" for support, advocacy or research.

American Parkinson Disease Association

As the country’s largest grassroots Parkinson’s disease organization, the American Parkinson Disease Association (APDA) improves the lives people with Parkinson’s disease and their families from coast to coast with patient/caregiver support; education and positive lifestyle programs; awareness, social and fundraising events; and scientific research funding at all levels. Through a national network of Chapters, Information & Referral Centers, more than 1,000 support groups, and eight Centers for Advanced Research, APDA delivers help for today and hope for tomorrow.

Last Updated: 23 Oct 2014

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National Parkinson Foundation

The National Parkinson Foundation is the only organization with a singular focus on improving the quality of Parkinson's care through research, education and outreach. We continue to bring help and hope to the estimated one million individuals in the US, four to six million worldwide, who are living with Parkinson's disease. NPF has funded more than $180 million in research and support services to improve the lives of people with PD. NPF programs touch more than one million people a year through our global network of Centers of Excellence, our US chapters, conferences, and online resources.

Last Updated: 23 Apr 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Parkinson disease 2" for support, advocacy or research.

American Parkinson Disease Association

As the country’s largest grassroots Parkinson’s disease organization, the American Parkinson Disease Association (APDA) improves the lives people with Parkinson’s disease and their families from coast to coast with patient/caregiver support; education and positive lifestyle programs; awareness, social and fundraising events; and scientific research funding at all levels. Through a national network of Chapters, Information & Referral Centers, more than 1,000 support groups, and eight Centers for Advanced Research, APDA delivers help for today and hope for tomorrow.

http://www.apdaparkinson.org

Last Updated: 23 Oct 2014

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National Parkinson Foundation

The National Parkinson Foundation is the only organization with a singular focus on improving the quality of Parkinson's care through research, education and outreach. We continue to bring help and hope to the estimated one million individuals in the US, four to six million worldwide, who are living with Parkinson's disease. NPF has funded more than $180 million in research and support services to improve the lives of people with PD. NPF programs touch more than one million people a year through our global network of Centers of Excellence, our US chapters, conferences, and online resources.

http://parkinson.org

Last Updated: 23 Apr 2014

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General Support Organizations

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General Resources

Aware in Care

Aware in Care aims to help people with Parkinson’s disease get the best care possible during a hospital stay.

Updated 8 Apr 2014

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What You and Your Family Should Know

This book offers a basic overview of Parkinson’s disease. Topics include symptoms, diagnosis, parkinsonism, treatment options, putting your health team together, accepting and adapting to PD, and staying well.

Updated 23 Apr 2014

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Caring and Coping

Written for care partners of people with Parkinson’s, this book profiles caregiver roles and activities. Topics include what to expect, care options, activities of daily living, legal and financial planning and taking care of yourself as caregiver.

Updated 23 Apr 2014

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Fitness Counts

Exercise is important at any stage of Parkinson’s. This book describes exercise methods that contribute to stability and includes photos to demonstrate proper form.

Updated 23 Apr 2014

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10 Early Warning Signs of Parkinson's Disease

This short brochure describes 10 symptoms that may be early signs of Parkinson’s disease. Each symptom of concern is listed along with what is "normal." If you have more than one symptom, you may want to visit your doctor.

Updated 23 Apr 2014

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Medications

This book describes both motor and non-motor symptoms of Parkinson’s and provides detailed information on common medications used to treat these symptoms.

Updated 23 Apr 2014

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Nutrition Matters

This book focuses on optimal nutrition for people with Parkinson’s and explains how PD affects the gastrointestinal system. It also offers tips and recipes to help manage non-motor symptoms and medication side effects.

Updated 23 Apr 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Parkinson disease 2" returned 19 free, full-text research articles on human participants. First 3 results:

Endoplasmic reticulum and lysosomal Ca²⁺ stores are remodelled in GBA1-linked Parkinson disease patient fibroblasts.
 

Author(s): Bethan S Kilpatrick, Joana Magalhaes, Michelle S Beavan, Alisdair McNeill, Matthew E Gegg, Michael W J Cleeter, Duncan Bloor-Young, Grant C Churchill, Michael R Duchen, Anthony H Schapira, Sandip Patel

Journal: Cell Calcium. 2016 Jan;59(1):12-20.

 

Mutations in β-glucocerebrosidase (encoded by GBA1) cause Gaucher disease (GD), a lysosomal storage disorder, and increase the risk of developing Parkinson disease (PD). The pathogenetic relationship between the two disorders is unclear. Here, we characterised Ca(2+) release in fibroblasts ...

Last Updated: 6 Feb 2016

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Quantitative Analysis of ¹⁸F-(E)-N-(3-Iodoprop-2-Enyl)-2β-Carbofluoroethoxy-3β-(4'-Methyl-Phenyl) Nortropane Binding to the Dopamine Transporter in Parkinson Disease.
 

Author(s): Patrik Fazio, Per Svenningsson, Anton Forsberg, Erik G Jönsson, Nahid Amini, Ryuji Nakao, Sangram Nag, Christer Halldin, Lars Farde, Andrea Varrone

Journal: J. Nucl. Med.. 2015 May;56(5):714-20.

 

(18)F-(E)-N-(3-iodoprop-2-enyl)-2β-carbofluoroethoxy-3β-(4'-methyl-phenyl) nortropane ((18)F-FE-PE2I) is a recently developed radioligand for the in vivo quantification of the dopamine transporter (DAT) in the striatum and substantia nigra (SN). The aim of this study was to examine ...

Last Updated: 2 May 2015

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Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease.
 

Author(s): Alexandria Beilina, Iakov N Rudenko, Alice Kaganovich, Laura Civiero, Hien Chau, Suneil K Kalia, Lorraine V Kalia, Evy Lobbestael, Ruth Chia, Kelechi Ndukwe, Jinhui Ding, Mike A Nalls, , , Maciej Olszewski, David N Hauser, Ravindran Kumaran, Andres M Lozano, Veerle Baekelandt, Lois E Greene, Jean-Marc Taymans, Elisa Greggio, Mark R Cookson

Journal: Proc. Natl. Acad. Sci. U.S.A.. 2014 Feb;111(7):2626-31.

 

Mutations in leucine-rich repeat kinase 2 (LRRK2) cause inherited Parkinson disease (PD), and common variants around LRRK2 are a risk factor for sporadic PD. Using protein-protein interaction arrays, we identified BCL2-associated athanogene 5, Rab7L1 (RAB7, member RAS oncogene family-like ...

Last Updated: 19 Feb 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Parkinson disease 2" returned 2 free, full-text review articles on human participants. First 3 results:

α-Synuclein, leucine-rich repeat kinase-2, and manganese in the pathogenesis of Parkinson disease.
 

Author(s): Jason P Covy, Benoit I Giasson

Journal: Neurotoxicology. 2011 Oct;32(5):622-9.

 

Parkinson disease (PD) is the most common movement disorder. It is characterized by bradykinesia, postural instability, resting tremor, and rigidity associated with the progressive loss of dopaminergic neurons in the substantia nigra pars compacta. Another pathological hallmark of ...

Last Updated: 24 Oct 2011

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The role of iron in Parkinson disease and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity.
 

Author(s): F Yantiri, J K Andersen

Journal: IUBMB Life. 1999 Aug;48(2):139-41.

 

Parkinson disease (PD) involves the specific degeneration of dopaminergic neurons of the pars compacta of the substantia nigra. Although the cause of the degeneration of nigrostriatal dopaminergic neurons in PD is unknown, there is significant evidence to suggest that oxidative stress ...

Last Updated: 25 May 2000

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Hereditary Parkinson s Disease Natural History Protocol
 

Status: Recruiting

Condition Summary: Parkinson Disease 6, Early-Onset; Parkinson Disease (Autosomal Recessive, Early Onset) 7, Human; Parkinson Disease Autosomal Recessive, Early Onset; Parkinson Disease, Autosomal Recessive Early-Onset, Digenic, Pink1/Dj1

 

Last Updated: 1 Dec 2016

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Parkinson's Families Project
 

Status: Recruiting

Condition Summary: Parkinson's Disease; Parkinsonism

 

Last Updated: 29 Apr 2016

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One-year Follow-up of Iron in Basal Ganglia - R2*: a Biomarker of Parkinson's Disease Progression?
 

Status: Recruiting

Condition Summary: Parkinson's Disease

 

Last Updated: 28 Jun 2016

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