Parkinson disease 2

Common Name(s)

Parkinson disease 2

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Parkinson disease 2" for support, advocacy or research.

National Parkinson Foundation

The National Parkinson Foundation is the only organization with a singular focus on improving the quality of Parkinson's care through research, education and outreach. We continue to bring help and hope to the estimated one million individuals in the US, four to six million worldwide, who are living with Parkinson's disease. NPF has funded more than $180 million in research and support services to improve the lives of people with PD. NPF programs touch more than one million people a year through our global network of Centers of Excellence, our US chapters, conferences, and online resources.

http://parkinson.org

Last Updated: 8 Apr 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Parkinson disease 2" for support, advocacy or research.

National Parkinson Foundation

The National Parkinson Foundation is the only organization with a singular focus on improving the quality of Parkinson's care through research, education and outreach. We continue to bring help and hope to the estimated one million individuals in the US, four to six million worldwide, who are living with Parkinson's disease. NPF has funded more than $180 million in research and support services to improve the lives of people with PD. NPF programs touch more than one million people a year through our global network of Centers of Excellence, our US chapters, conferences, and online resources.

http://parkinson.org

Last Updated: 8 Apr 2014

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General Support Organizations

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General Resources

Aware in Care

Aware in Care aims to help people with Parkinson’s disease get the best care possible during a hospital stay.

Updated 8 Apr 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Parkinson disease 2" returned 13 free, full-text research articles on human participants. First 3 results:

Is Parkinson disease associated with lysosomal integral membrane protein type-2?: challenges in interpreting association data.
 

Author(s): Emerson Maniwang, Nahid Tayebi, Ellen Sidransky

Journal: Mol. Genet. Metab.. 2013 Apr;108(4):269-71.

 

Several genetic risk factors have been identified for Parkinson disease (PD), including mutations in glucocerebrosidase (GBA1). Recently, two single nucleotide polymorphisms (SNPs) described as SCARB2 SNPs were reported to be associated with PD. SCARB2 is an attractive candidate gene ...

Last Updated: 13 Mar 2013

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Metabolism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by mitochondrion-targeted cytochrome P450 2D6: implications in Parkinson disease.
 

Author(s): Prachi Bajpai, Michelle C Sangar, Shilpee Singh, Weigang Tang, Seema Bansal, Goutam Chowdhury, Qian Cheng, Ji-Kang Fang, Martha V Martin, F Peter Guengerich, Narayan G Avadhani

Journal: J. Biol. Chem.. 2013 Feb;288(6):4436-51.

 

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is a neurotoxic side product formed in the chemical synthesis of desmethylprodine opioid analgesic, which induces Parkinson disease. Monoamine oxidase B, present in the mitochondrial outer membrane of glial cells, catalyzes the oxidation ...

Last Updated: 11 Feb 2013

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Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutations.
 

Author(s): Bernd K Gilsbach, Franz Y Ho, Ingrid R Vetter, Peter J M van Haastert, Alfred Wittinghofer, Arjan Kortholt

Journal: Proc. Natl. Acad. Sci. U.S.A.. 2012 Jun;109(26):10322-7.

 

Mutations in human leucine-rich-repeat kinase 2 (LRRK2) have been found to be the most frequent cause of late-onset Parkinson disease. Here we show that Dictyostelium discoideum Roco4 is a suitable model to study the structural and biochemical characteristics of the LRRK2 kinase and ...

Last Updated: 27 Jun 2012

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Parkinson disease 2" returned 1 free, full-text review articles on human participants. First 3 results:

α-Synuclein, leucine-rich repeat kinase-2, and manganese in the pathogenesis of Parkinson disease.
 

Author(s): Jason P Covy, Benoit I Giasson

Journal: Neurotoxicology. 2011 Oct;32(5):622-9.

 

Parkinson disease (PD) is the most common movement disorder. It is characterized by bradykinesia, postural instability, resting tremor, and rigidity associated with the progressive loss of dopaminergic neurons in the substantia nigra pars compacta. Another pathological hallmark of ...

Last Updated: 24 Oct 2011

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Mutations Associated With Parkinson s Disease
 

Status: Recruiting

Condition Summary: Parkinson's Disease

 

Last Updated: 14 Mar 2014

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Last Updated: 18 Sep 2013

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Last Updated: 16 Apr 2014

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