Osteoarthritis

Common Name(s)

Osteoarthritis

Osteoarthritis is one of the most common forms of arthritis. It is a chronic condition in which the material that cushions the joints, called cartilage, breaks down. This causes the bones to rub against each other, causing stiffness, pain and loss of joint movement. Common symptoms are sore or stiff joints, particularly the hips, knees, and lower back, but osteoarthritis may also affect the neck, small finger joints, the base of the thumb, ankle, and big toe. The pain may be moderate and come and go, without affecting the ability to perform daily tasks. Some people’s OA will never progress past this early stage. Others will have their OA get worse. The pain and stiffness of more severe osteoarthritis may make it difficult to walk, climb stairs, sleep, or perform other daily tasks.

About 27 million people in the United States have osteoarthritis. The cause is not fully understood and no cure exists but osteoarthritis treatments can slow the progression of the disease, relieve pain and improve joint function. Common risk factors include increasing age, obesity, previous joint injury, overuse of the joint, weak thigh muscles, and genetics.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Osteoarthritis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Osteoarthritis" returned 5616 free, full-text research articles on human participants. First 3 results:

Combined effects of reproductive and hormone factors and obesity on the prevalence of knee osteoarthritis and knee pain among middle-aged or older Chinese women: a cross-sectional study.
 

Author(s): Min Zhou, Jianghao Chen, Dongming Wang, Chunmei Zhu, Youjie Wang, Weihong Chen

Journal:

 

Knee osteoarthritis (KOA) is one form of degenerative arthritis that results from the breakdown of cartilage and underlying bone. The prevalence of KOA is considerably higher in women than in men; however, the reason for this difference has not been thoroughly elucidated to date. ...

Last Updated: 31 Dec 1969

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Rivaroxaban improves hidden blood loss, blood transfusion rate and reduces swelling of the knee joint in knee osteoarthritis patients after total knee replacement.
 

Author(s): Yi-Min Zhang, Jian-Yong Liu, Xue-Dong Sun, Miao Zhang, Xiao-Guang Liu, Xiu-Li Chen

Journal: Medicine (Baltimore). 2018 Oct;97(40):e12630.

 

Osteoarthritis (OA) is the third most common diagnosis made by general practitioners in older patients. The purpose of the current study is to investigate effects rivaroxaban had on both hidden blood loss and blood transfusion rate (BTR) in patients with knee OA (KOA) after going ...

Last Updated: 31 Dec 1969

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Response to: Comment on "Responders to Platelet-Rich Plasma in Osteoarthritis: A Technical Analysis".
 

Author(s): Christophe Milants, Olivier Bruyère, Jean-François Kaux

Journal:

 

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Osteoarthritis" returned 933 free, full-text review articles on human participants. First 3 results:

Comparison of platelet-rich plasma vs hyaluronic acid injections in patients with knee osteoarthritis: A protocol for a systematic review and meta-analysis.
 

Author(s): Yan-Hong Han, He-Tao Huang, Jian-Ke Pan, Jiong-Tong Lin, Ling-Feng Zeng, Gui-Hong Liang, Wei-Yi Yang, Jun Liu

Journal: Medicine (Baltimore). 2018 Nov;97(44):e13049.

 

Knee osteoarthritis (KOA) is a progressive joint disease involving intraarticular and periarticular structures. In recent years, there has been increasing interest in the use of autologous growth factors, such as intraarticular injections of platelet-rich plasma (PRP), to treat KOA. ...

Last Updated: 31 Dec 1969

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The association between rs12885713 polymorphism in CALM1 and risk of osteoarthritis: A meta-analysis of case-control studies.
 

Author(s): Jia Shi, Shu-Tao Gao, Zheng-Tao Lv, Wei-Bin Sheng, Hao Kang

Journal: Medicine (Baltimore). 2018 Sep;97(36):e12235.

 

The single nucleotide polymorphism (SNP) rs12885713 of calmodulin 1 gene (CALM1) has been reported to involve in the etiology of osteoarthritis (OA) in several association studies with limited sample size and conflicting results. The purpose of the present systematic review and meta-analysis ...

Last Updated: 31 Dec 1969

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Bone quality, and the combination and penetration of cement-bone interface: A comparative micro-CT study of osteoarthritis and rheumatoid arthritis.
 

Author(s): Yuanzheng Song, Fahao Zhu, Feng Lin, Feng Zhang, Shuaigong Zhang

Journal: Medicine (Baltimore). 2018 Aug;97(35):e11987.

 

To compare the microstructure, bone quality, and the combination and penetration of cement-bone interface in tissue specimens from patients with osteoarthritis (OA) and rheumatoid arthritis (RA).A total of 80 femoral condyle tissue specimens from 20 OA patients (40 condyles) and 20 ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Crucumin Effects on the Immune System in Osteoarthritis Patients
 

Status: Not yet recruiting

Condition Summary: Osteoarthritis

 

Last Updated: 3 Nov 2018

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Feasibility of High Intensity Interval Training in Knee Osteoarthritis
 

Status: Recruiting

Condition Summary: Knee Osteoarthritis

 

Last Updated: 11 Dec 2017

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The Study to Evaluate Efficacy and Safety of Celecoxib Capsule in Hand Osteoarthritis Patients
 

Status: Recruiting

Condition Summary: Osteoarthritis Hand

 

Last Updated: 24 Feb 2017

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