Feingold syndrome

Common Name(s)

Feingold syndrome, Oculodigitoesophagoduodenal syndrome

Feingold syndrome is an autosomal dominant disorder characterized by variable combinations of microcephaly, limb malformations, esophageal and duodenal atresias, and learning disability/mental retardation. Hand and foot abnormalities may include hypoplastic thumbs, clinodactyly of second and fifth fingers, syndactyly (characteristically between second and third and fourth and fifth toes), and shortened or absent middle phalanges. Cardiac and renal malformations, vertebral anomalies, and deafness have also been described in a minority of patients (summary by {23:Teszas et al., 2006}). Genetic Heterogeneity of Feingold Syndrome Feingold syndrome-2 (FGLDS2; {614326}) is caused by hemizygous deletion of the MIR17HG gene ({609415}) on chromosome 13q31.3.
 

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Condition Specific Organizations

Following organizations serve the condition "Feingold syndrome" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Feingold syndrome" returned 2 free, full-text research articles on human participants. First 3 results:

[Association esophageal atresia type 3 - microcephaly: an incomplete Feingold syndrome?].
 

Author(s): Mick Yapongombo Shongo, Toni Kasole Lubala, Sébastien Musanzayi Mbuyi, Paul Ilunga Makinko, Dieudonné Tshikwej Ngwej, Felix Numbi Kabange

Journal: Pan Afr Med J. 2012 ;13():85.

 

Last Updated: 11 Feb 2013

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Dissection of the MYCN locus in Feingold syndrome and isolated oesophageal atresia.
 

Author(s): Marie Cognet, Agnés Nougayrede, Valérie Malan, Patrick Callier, Celia Cretolle, Laurence Faivre, David Genevieve, Alice Goldenberg, Delphine Heron, Sandra Mercier, Nicole Philip, Sabine Sigaudy, Alain Verloes, Sabine Sarnacki, Arnold Munnich, Michel Vekemans, Stanislas Lyonnet, Heather Etchevers, Jeanne Amiel, Loïc de Pontual

Journal: Eur. J. Hum. Genet.. 2011 May;19(5):602-6.

 

Feingold syndrome (FS) is a syndromic microcephaly entity for which MYCN is the major disease-causing gene. We studied the expression pattern of MYCN at different stages of human embryonic development and collected a series of 17 FS and 12 isolated oesophageal atresia (IOA) cases. ...

Last Updated: 25 Apr 2011

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Reviews from the PubMed Database

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The terms "Feingold syndrome" returned 0 free, full-text review articles on human participants.

 
 
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