Neuroblastoma 2

Common Name(s)

Neuroblastoma 2

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Neuroblastoma 2" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Neuroblastoma 2" returned 157 free, full-text research articles on human participants. First 3 results:

PHOX2A and PHOX2B are differentially regulated during retinoic acid-driven differentiation of SK-N-BE(2)C neuroblastoma cell line.
 

Author(s): Simona Di Lascio, Elena Saba, Debora Belperio, Andrea Raimondi, Helen Lucchetti, Diego Fornasari, Roberta Benfante

Journal: Exp. Cell Res.. 2016 Mar;342(1):62-71.

 

PHOX2B and its paralogue gene PHOX2A are two homeodomain proteins in the network regulating the development of autonomic ganglia that have been associated with the pathogenesis of neuroblastoma (NB), because of their over-expression in different NB cell lines and tumour samples. We ...

Last Updated: 18 Mar 2016

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Select Bcl-2 antagonism restores chemotherapy sensitivity in high-risk neuroblastoma.
 

Author(s): Rachel Tanos, Dipan Karmali, Srilatha Nalluri, Kelly C Goldsmith

Journal:

 

Pediatric patients with high-risk neuroblastoma (HR NB) often fail to respond to upfront intensive multimodal therapy. Tumor-acquired suppression of apoptosis contributes to therapy resistance. Many HR NB tumors depend on the anti-apoptotic protein Bcl-2 for survival, through Bcl-2 ...

Last Updated: 15 Feb 2016

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Transcription factor activating protein 2 beta (TFAP2B) mediates noradrenergic neuronal differentiation in neuroblastoma.
 

Author(s): Fakhera Ikram, Sandra Ackermann, Yvonne Kahlert, Ruth Volland, Frederik Roels, Anne Engesser, Falk Hertwig, Hayriye Kocak, Barbara Hero, Daniel Dreidax, Kai-Oliver Henrich, Frank Berthold, Peter N├╝rnberg, Frank Westermann, Matthias Fischer

Journal: Mol Oncol. 2016 Feb;10(2):344-59.

 

Neuroblastoma is an embryonal pediatric tumor that originates from the developing sympathetic nervous system and shows a broad range of clinical behavior, ranging from fatal progression to differentiation into benign ganglioneuroma. In experimental neuroblastoma systems, retinoic ...

Last Updated: 3 Feb 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Neuroblastoma 2" returned 1 free, full-text review articles on human participants. First 3 results:

The development of antibody-IL-2 based immunotherapy with hu14.18-IL2 (EMD-273063) in melanoma and neuroblastoma.
 

Author(s): Brett H Yamane, Jacquelyn A Hank, Mark R Albertini, Paul M Sondel

Journal: Expert Opin Investig Drugs. 2009 Jul;18(7):991-1000.

 

Patients with high risk melanoma and neuroblastoma frequently experience recurrence despite surgical resection and appropriate adjuvant therapies. Immunotherapy with the immunocytokine hu14.18-IL2 (EMD-273063) was developed by means of fusion of two molecules of IL-2 to the monoclonal ...

Last Updated: 24 Jun 2009

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Anti-GD2 3F8 Monoclonal Antibody and GM-CSF for High-Risk Neuroblastoma
 

Status: Recruiting

Condition Summary: Neuroblastoma

 

Last Updated: 9 Jan 2017

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Humanized Anti-GD2 Antibody Hu3F8 and Allogeneic Natural Killer Cells for High-Risk Neuroblastoma
 

Status: Recruiting

Condition Summary: Neuroblastoma; High-Risk

 

Last Updated: 14 Sep 2016

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4SCAR-GD2 Targeting Refractory and/or Recurrent Neuroblastoma
 

Status: Recruiting

Condition Summary: Neuroblastoma; Effects of Immunotherapy

 

Last Updated: 4 May 2016

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