Myoepithelial carcinoma

Common Name(s)

Myoepithelial carcinoma

Myoepithelial carcinoma is a rare malignant tumor that usually occurs in the salivary glands but can also occur in skin and soft tissues. The name of this cancer comes from the appearance of the tumor cells under the microscope. Approximately 66% of these tumors occur in the parotid gland. The average age of patients is reported to be 55 years.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Myoepithelial carcinoma" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Myoepithelial carcinoma" returned 31 free, full-text research articles on human participants. First 3 results:

Myoepithelial carcinoma of pharynx expressing KIT and PDGFRA.
 

Author(s): Tadashi Terada

Journal: Int J Clin Exp Pathol. 2013 ;6(2):314-7.

 

KIT and PDGFRA expression has rarely been examined in myoepithelial carcinoma (MC) of the salivary glands. An 89-year-old Japanese woman presented with a pharyngeal mass. Gross and imaging examinations revealed an elevated mass in the middle pharynx next to the oral cavity. A biopsy ...

Last Updated: 18 Jan 2013

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NR4A3 rearrangement reliably distinguishes between the clinicopathologically overlapping entities myoepithelial carcinoma of soft tissue and cellular extraskeletal myxoid chondrosarcoma.
 

Author(s): Uta Flucke, Bastiaan B J Tops, Marian A J Verdijk, Patricia J H van Cleef, Peter H van Zwam, Pieter J Slootweg, Judith V M G Bovée, Robert G Riedl, David H Creytens, Albert J H Suurmeijer, Thomas Mentzel

Journal: Virchows Arch.. 2012 Jun;460(6):621-8.

 

Myoepithelial carcinoma of soft tissue (MEC) and cellular extraskeletal myxoid chondrosarcoma (cEMC) share striking similarities. In this paper, we compare ten MECs with five cEMCs. MEC patients had an equal gender distribution. The age range was 15-76 years (mean, 42 years). Tumours ...

Last Updated: 11 Jun 2012

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The prognostic significance of p63 and Ki-67 expression in myoepithelial carcinoma.
 

Author(s): You-Hua Jiang, Bo Cheng, Ming-Hua Ge, Gu Zhang

Journal:

 

Myoepithelial carcinoma is a rare tumour. The clinical and biological behaviours of these tumours are variable. Although many factors have been evaluated as potential prognostic indicators, including clinical stage, site and size of the tumour, high proliferative activity, extensive ...

Last Updated: 23 Apr 2012

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Myoepithelial carcinoma" returned 6 free, full-text review articles on human participants. First 3 results:

[Epithelial-myoepithelial carcinoma of parotid gland: a tumor of low grade malignancy?].
 

Author(s): Daniela Fonte, Lúcia Nunes Aguas, Lurdes Alves, Carlos Sotto-Mayor, Gabriela Pinto

Journal: Acta Med Port. 2011 Dec;24 Suppl 3():675-80.

 

Epithelial-myoepithelial carcinoma (EMC) is a rare tumor with predilection for the major salivary glands, mainly the parotid gland. It is a tumor of low grade malignancy, and despite its tendency to local recurrence with low metastatic potential, rare cases of EMC may have an aggressive ...

Last Updated: 3 Aug 2012

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Lacrimal gland adenoid cystic carcinoma with high-grade transformation to myoepithelial carcinoma: report of a case and review of literature.
 

Author(s): Prokopios P Argyris, Stefan E Pambuccian, Zuzan Cayci, Charanjeet Singh, Konstantinos I Tosios, Ioannis G Koutlas

Journal: Head Neck Pathol. 2013 Mar;7(1):85-92.

 

Adenoid cystic carcinoma (AdCC) is the most frequent malignant neoplasm of the lacrimal glands. Like its salivary gland counterpart, lacrimal AdCC can rarely undergo high-grade transformation ("dedifferentiation"). We herein report the clinical, radiographic and microscopic findings ...

Last Updated: 15 Mar 2013

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Anaplastic myoepithelial carcinoma of the sinonasal tract: an underrecognized salivary-type tumor among the sinonasal small round blue cell malignancies? Report of one case and a review of the literature.
 

Author(s): Fredrik Petersson, Siew Shuen Chao, Siok Bian Ng

Journal: Head Neck Pathol. 2011 Jun;5(2):144-53.

 

We present a 45 year old female patient with a nasal carcinoma showing high-grade/anaplastic histomorphological features and with a distinct myoepithelial immunohistochemical phenotype including positivity for smooth muscle actin, p63, S100 protein with no sustentacular pattern, calponin, ...

Last Updated: 20 May 2011

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.