Myoepithelial carcinoma

Common Name(s)

Myoepithelial carcinoma

Myoepithelial carcinoma is a rare malignant tumor that usually occurs in the salivary glands but can also occur in skin and soft tissues. The name of this cancer comes from the appearance of the tumor cells under the microscope. Approximately 66% of these tumors occur in the parotid gland. The average age of patients is reported to be 55 years.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Myoepithelial carcinoma" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Myoepithelial carcinoma" returned 61 free, full-text research articles on human participants. First 3 results:

Epithelial-myoepithelial carcinoma with high-grade transformation of parotid gland: A case report and literature review.
 

Author(s): Bowen Li, Hongyu Yang, Xia Hong, Yufan Wang, Feng Wang

Journal: Medicine (Baltimore). 2017 Dec;96(49):e8988.

 

Epithelial-myoepithelial carcinoma (EMC) is regarded as a rare low-grade malignant tumor of the salivary gland, accounting for 0.4% to 1% of all salivary gland tumors. However, epithelial-myoepithelial carcinoma with high-grade transformation (EMC with HGT) is extremely rare, therefore ...

Last Updated: 31 Dec 1969

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Myoepithelial carcinoma with RB1 mutation: remarkable chemosensitivity to carcinoma of unknown origin therapy.
 

Author(s): Timothy M Hoggard, Evita Henderson-Jackson, Marilyn M Bui, Jamie Caracciolo, Jamie K Teer, Sean Yoder, Odion Binitie, Ricardo J Gonzalez, Andrew S Brohl, Damon R Reed

Journal:

 

Myoepithelial carcinoma of soft tissue is a rare, malignant neoplasm that is morphologically and immunophenotypically similar to its counterpart in salivary gland. It demonstrates myoepithelial differentiation, possessing both epithelial and myogenic characteristics. Thought to be ...

Last Updated: 31 Dec 1969

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Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function.
 

Author(s): Muge Sarper, Michael D Allen, Jenny Gomm, Linda Haywood, Julie Decock, Sally Thirkettle, Ahsen Ustaoglu, Shah-Jalal Sarker, John Marshall, Dylan R Edwards, J Louise Jones

Journal:

 

Normal myoepithelial cells (MECs) play an important tumour-suppressor role in the breast but display an altered phenotype in ductal carcinoma in situ (DCIS), gaining tumour-promoter functions. Matrix metalloproteinase-8 (MMP-8) is expressed by normal MECs but is lost in DCIS. This ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Myoepithelial carcinoma" returned 12 free, full-text review articles on human participants. First 3 results:

A rare case of primary peripheral epithelial myoepithelial carcinoma of lung: Case report and literature review.
 

Author(s): Cheng Shen, Xin Wang, Guowei Che

Journal: Medicine (Baltimore). 2016 Aug;95(35):e4371.

 

Primary salivary gland-type tumors of lung are rare. Epithelial-myoepithelial carcinoma (EMC) of the lung is a minor salivary gland-type tumor subtype.

Last Updated: 31 Dec 1969

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Epithelial-myoepithelial carcinoma arising from the subglottis: a case report and review of the literature.
 

Author(s): Hun-Jae Oh, Nam-yong Do, Keun-Hong Kee, Jun-Hee Park

Journal:

 

Epithelial-myoepithelial carcinoma is an extremely rare disease that usually occurs in the parotid gland but can occur in a variety of sites such as the nasal cavity, paranasal sinus, and base of the tongue.

Last Updated: 31 Dec 1969

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Primary myoepithelial carcinoma of the lung: a case report and review of literature.
 

Author(s): Jianguo Wei, Xiaolu Yuan, Yuying Yao, Liping Sun, Xiaofei Yao, Aijing Sun

Journal:

 

Primary myoepithelial carcinoma of the lung is a very rare tumor arising from the salivary glands of the respiratory epithelium. Since it was first described by Higashiyama et al. in 1998, to the best of our knowledge, only eight actual cases reported in the English-language literature ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.