Mycosis fungoides

Common Name(s)

Mycosis fungoides

Mycosis fungoides is a disease in which T-cell lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin. This condition is one of the most common types of T-cell lymphoma. Mycosis fungoides is characterized by a scaly, red rash that develops on the skin, particularly on areas that are not usually exposed to the sun. The rash may last for months or years without causing any symptoms. Over time, a thin, reddened, eczema-like rash may develop, followed by thickened, red patches of skin. Finally, tumors form which may develop into ulcers and become infected. Mycosis fungoides is difficult to cure. Treatment is usually palliative, with the intention of relieving symptoms and improving the quality of life.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Mycosis fungoides" for support, advocacy or research.

Cutaneous Lymphoma Foundation

The Cutaneous Lymphoma Foundation is an independent, nonprofit patient advocacy organization whose mission is supporting every person with cutaneous lymphoma by promoting awareness and education, advancing patient care and facilitating research.

Last Updated: 6 Jan 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Mycosis fungoides" for support, advocacy or research.

Cutaneous Lymphoma Foundation

The Cutaneous Lymphoma Foundation is an independent, nonprofit patient advocacy organization whose mission is supporting every person with cutaneous lymphoma by promoting awareness and education, advancing patient care and facilitating research.

http://www.clfoundation.org

Last Updated: 6 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Mycosis fungoides" returned 370 free, full-text research articles on human participants. First 3 results:

Hyperpigmentation as a peculiar presentation of mycosis fungoides.
 

Author(s): Ying-Yi Lu, Chieh-Hsin Wu, Chun-Ching Lu, Chien-Hui Hong

Journal: An Bras Dermatol. 2017 ;92(5 Suppl 1):92-94.

 

Hyperpigmented mycosis fungoides is an extremely rare subtype of mycosis fungoides. It presents as multiple pigmented macules and patches without poikilodermatous changes and characterized by a CD8+ phenotype on immunohistochemistry. This report describes a typical case of hyperpigmented ...

Last Updated: 31 Dec 1969

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Folliculotropic mycosis fungoides: challenging clinical, histopathological and immunohistochemical diagnosis.
 

Author(s): Maria Isabel Braga Malveira, Gianne Pascoal, Shirley Braga Lima Gamonal, Maria Christina Marques Nogueira Castañon

Journal: An Bras Dermatol. 2017 ;92(5 Suppl 1):73-75.

 

Mycosis fungoides is a cutaneous T-cell lymphoma with various clinical and pathological presentations. Early lesions are nonspecific, which hinders early diagnosis. The folliculotropic subtype is manifested as acneiform lesions, follicular papules or erythematous plaques mainly on ...

Last Updated: 31 Dec 1969

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Granulomatous slack skin: a rare subtype of mycosis fungoides.
 

Author(s): Letícia Marra da Motta, Cleverson Teixeira Soares, Sadamitsu Nakandakari, Gardênia Viana da Silva, Maria Helena Mazzi Freire Nigro, Leticia Stella Gardini Brandão

Journal: An Bras Dermatol. ;92(5):694-697.

 

We report a case of granulomatous slack skin, a rare and indolent subtype of mycosis fungoides. It affects mainly men between the third and fourth decades. It is characterized by hardened and erithematous plaques that mainly affect flexural areas and become pedunculated after some ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Mycosis fungoides" returned 41 free, full-text review articles on human participants. First 3 results:

European Organisation for Research and Treatment of Cancer consensus recommendations for the treatment of mycosis fungoides/Sézary syndrome - Update 2017.
 

Author(s): Franz Trautinger, Johanna Eder, Chalid Assaf, Martine Bagot, Antonio Cozzio, Reinhard Dummer, Robert Gniadecki, Claus-Detlev Klemke, Pablo L Ortiz-Romero, Evangelia Papadavid, Nicola Pimpinelli, Pietro Quaglino, Annamari Ranki, Julia Scarisbrick, Rudolf Stadler, Liisa Väkevä, Maarten H Vermeer, Sean Whittaker, Rein Willemze, Robert Knobler

Journal: Eur. J. Cancer. 2017 05;77():57-74.

 

In order to provide a common standard for the treatment of mycosis fungoides (MF) and Sézary syndrome (SS), the European Organisation for Research and Treatment of Cancer-Cutaneous Lymphoma Task Force (EORTC-CLTF) published in 2006 its consensus recommendations for the stage-adapted ...

Last Updated: 31 Dec 1969

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The biomarker landscape in mycosis fungoides and Sézary syndrome.
 

Author(s): Brittany Dulmage, Larisa Geskin, Joan Guitart, Oleg E Akilov

Journal: Exp. Dermatol.. 2017 08;26(8):668-676.

 

The practice of pre-emptive individualized medicine is predicated on the discovery, development and application of biomarkers in specific clinical settings. Mycosis fungoides and Sézary syndrome are the two most common type of cutaneous T-cell lymphoma, yet diagnosis, prognosis and ...

Last Updated: 31 Dec 1969

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Mycosis fungoides staged by 18F-flurodeoxyglucose positron emission tomography/computed tomography: Case report and review of literature.
 

Author(s): Lu Xu, Hua Pang, Jin Zhu, Xi Chen, Lili Guan, Jie Wang, Jing Chen, Ying Liu

Journal: Medicine (Baltimore). 2016 Nov;95(45):e5044.

 

Mycosis fungoides is a kind of malignant lymphoma arising from T cells, but primarily occurs in skin, and it is the most common type of cutaneous lymphoma. Mycosis fungoides (MF) is a rare non-Hodgkin lymphoma but the most common type of primary cutaneous T-cell lymphomas. Because ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Safety and Effectiveness of A-dmDT390-bisFv(UCHT1) Fusion Protein in Subjects With Mycosis Fungoides
 

Status: Not yet recruiting

Condition Summary: Mycosis Fungoides

 

Last Updated: 21 Oct 2016

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Photodynamic Therapy in Treating Patients With Refractory Mycosis Fungoides
 

Status: Recruiting

Condition Summary: Refractory Mycosis Fungoides

 

Last Updated: 16 Nov 2017

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Ultra Low Dose Radiation for Local Treatment of Cutaneous Mycosis Fungoides
 

Status: Recruiting

Condition Summary: Mycosis Fungoides; Malignant Neoplasms Stated as Primary Lymphoid Haematopoietic

 

Last Updated: 2 May 2018

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