Mycosis fungoides

Common Name(s)

Mycosis fungoides

Mycosis fungoides is a disease in which T-cell lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin. This condition is one of the most common types of T-cell lymphoma. Mycosis fungoides is characterized by a scaly, red rash that develops on the skin, particularly on areas that are not usually exposed to the sun. The rash may last for months or years without causing any symptoms. Over time, a thin, reddened, eczema-like rash may develop, followed by thickened, red patches of skin. Finally, tumors form which may develop into ulcers and become infected. Mycosis fungoides is difficult to cure. Treatment is usually palliative, with the intention of relieving symptoms and improving the quality of life.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Mycosis fungoides" for support, advocacy or research.

Cutaneous Lymphoma Foundation

The Cutaneous Lymphoma Foundation is an independent, nonprofit patient advocacy organization whose mission is supporting every person with cutaneous lymphoma by promoting awareness and education, advancing patient care and facilitating research.

Last Updated: 6 Jan 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Mycosis fungoides" for support, advocacy or research.

Cutaneous Lymphoma Foundation

The Cutaneous Lymphoma Foundation is an independent, nonprofit patient advocacy organization whose mission is supporting every person with cutaneous lymphoma by promoting awareness and education, advancing patient care and facilitating research.

http://www.clfoundation.org

Last Updated: 6 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Mycosis fungoides" returned 421 free, full-text research articles on human participants. First 3 results:

Hyperpigmented mycosis fungoides with ecthyma gangrenosum.
 

Author(s): V V Pai, N N Kikkeri, S C Athanikar, V Rai, U S Dinesh

Journal: Indian J Cancer. ;52(1):79-80.

 

Last Updated: 3 Feb 2016

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Flow Cytometric Analysis of T, B, and NK Cells Antigens in Patients with Mycosis Fungoides.
 

Author(s): Serkan Yazıcı, Emel Bülbül Başkan, Ferah Budak, Barbaros Oral, Şaduman Balaban Adim, Zübeyde Ceylan Kalin, Güven Özkaya, Kenan Aydoğan, Hayriye Saricaoğlu, Şükran Tunali

Journal: J Immunol Res. 2015 ;2015():856340.

 

We retrospectively analyzed the clinicopathological correlation and prognostic value of cell surface antigens expressed by peripheral blood mononuclear cells in patients with mycosis fungoides (MF). 121 consecutive MF patients were included in this study. All patients had peripheral ...

Last Updated: 20 Jan 2016

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Mycosis Fungoides: A Retrospective Study of 44 Swedish Cases.
 

Author(s): Yvonne Eklund, Annika Aronsson, Artur Schmidtchen, Thomas Relander

Journal: Acta Derm. Venereol.. 2016 Jun;96(5):669-73.

 

Mycosis fungoides (MF) is a primary cutaneous T-cell lymphoma with slow disease progression. There is a lack of descriptive data from Sweden concerning patients with this diagnosis. This study extracted data on patients admitted to the dermatology department at Lund University Hospital, ...

Last Updated: 15 Jun 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Mycosis fungoides" returned 39 free, full-text review articles on human participants. First 3 results:

Hematopoietic Stem Cell Transplant for Mycosis Fungoides and Sézary Syndrome.
 

Author(s): Pooja Virmani, Jasmine Zain, Steven T Rosen, Patricia L Myskowski, Christiane Querfeld

Journal: Dermatol Clin. 2015 Oct;33(4):807-18.

 

Mycosis fungoides (MF) and Sézary syndrome (SS) are common types of primary cutaneous T-cell lymphoma. Early-stage MF has a favorable prognosis and responds well to skin-directed regimens. Patients with advanced-stage MF, transformed MF, and SS are treated with combined systemic ...

Last Updated: 5 Oct 2015

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Extracorporeal Photopheresis in the Treatment of Mycosis Fungoides and Sézary Syndrome.
 

Author(s): John A Zic

Journal: Dermatol Clin. 2015 Oct;33(4):765-76.

 

Extracorporeal photopheresis (ECP) is an immunomodulating procedure that leads to an expansion of peripheral blood dendritic cell populations and an enhanced TH1 immune response in cutaneous T-cell lymphoma (CTCL). Because of its excellent side effect profile and moderate efficacy, ...

Last Updated: 5 Oct 2015

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Phototherapy of Mycosis Fungoides.
 

Author(s): Emmilia Hodak, Lev Pavlovsky

Journal: Dermatol Clin. 2015 Oct;33(4):697-702.

 

Therapies based on ultraviolet light have long been established in mycosis fungoides (MF). They have traditionally included whole-body ultraviolet light B, both broad-band and narrow-band, and psoralen plus ultraviolet A. Phototherapy may be applied alone in early stage MF or in combination ...

Last Updated: 5 Oct 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Safety and Effectiveness of A-dmDT390-bisFv(UCHT1) Fusion Protein in Subjects With Mycosis Fungoides
 

Status: Not yet recruiting

Condition Summary: Mycosis Fungoides

 

Last Updated: 21 Oct 2016

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Stem Cell Transplant Therapy With Campath-1H for Treating Advanced Mycosis Fungoides and Sezary Syndrome
 

Status: Recruiting

Condition Summary: Mycosis Fungoides; Sezary Syndrome

 

Last Updated: 18 Nov 2016

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