Morquio Syndrome

Common Name(s)

Morquio Syndrome

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Morquio Syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Morquio Syndrome" returned 22 free, full-text research articles on human participants. First 3 results:

MRI morphometric characterisation of the paediatric cervical spine and spinal cord in children with MPS IVA (Morquio-Brailsford syndrome).
 

Author(s): Guirish A Solanki, William B Lo, Christian J Hendriksz

Journal: J. Inherit. Metab. Dis.. 2013 Mar;36(2):329-37.

 

Nearly all children with MPS IVA develop skeletal deformities affecting the spine. At the atlanto-axial spine, odontoid hypoplasia occurs. GAG deposition around the dens, leads to peri-odontoid infiltration. Transverse/alar ligament incompetence causes instability. Atlanto-axial instability ...

Last Updated: 7 Mar 2013

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In vivo confocal microscopy of the cornea in Morquio syndrome.
 

Author(s): S Stewart, C N J McGhee, D V Patel

Journal: Eye (Lond). 2012 Oct;26(10):1394-5.

 

Last Updated: 11 Oct 2012

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Mucopolysaccharidoses type IV A (Morquio syndrome): a case series of three siblings.
 

Author(s): P Rekka, P V Rathna, S Jagadeesh, S Seshadri

Journal: J Indian Soc Pedod Prev Dent. ;30(1):66-9.

 

Mucopolysaccharidoses (MPS) are a family of inherited metabolic diseases that results from the deficiency of lysosomal enzymes involved in the degradation of the glycosaminoglycans (mucopolysaccharides). Despite the well-documented oral and dental findings of MPS type IV, there is ...

Last Updated: 8 May 2012

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Morquio Syndrome" returned 2 free, full-text review articles on human participants. First 3 results:

Spinal involvement in mucopolysaccharidosis IVA (Morquio-Brailsford or Morquio A syndrome): presentation, diagnosis and management.
 

Author(s): Guirish A Solanki, Kenneth W Martin, Mary C Theroux, Christina Lampe, Klane K White, Renée Shediac, Christian G Lampe, Michael Beck, William G Mackenzie, Christian J Hendriksz, Paul R Harmatz

Journal: J. Inherit. Metab. Dis.. 2013 Mar;36(2):339-55.

 

Mucopolysaccharidosis IVA (MPS IVA), also known as Morquio-Brailsford or Morquio A syndrome, is a lysosomal storage disorder caused by a deficiency of the enzyme N-acetyl-galactosamine-6-sulphate sulphatase (GALNS). MPS IVA is multisystemic but manifests primarily as a progressive ...

Last Updated: 7 Mar 2013

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[Mucopolysaccharidosis IVA (Morquio A syndrome): clinical, biological and therapeutic aspects].
 

Author(s): H Bouzidi, S Khedhiri, S Laradi, S Ferchichi, M Daudon, A Miled

Journal: Ann. Biol. Clin. (Paris). ;65(1):5-11.

 

Mucopolysaccharidosis IVA (MPS IVA; Morquio A disease) is an autosomal recessive lysosomal storage disorder caused by a genetic deficiency of the N-acetylgalactosamine-6-sulfate sulfatase (GALNS; E.C.3.1.6.4). GALNS is required to degrade keratan sulfate (KS) and chondroitine-6-sulfate ...

Last Updated: 31 Jan 2007

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Biomarker for Morquio Disease
 

Status: Recruiting

Condition Summary: Lysosomal Storage Diseases; Morquio Disease

 

Last Updated: 7 Nov 2013

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Gait Analysis in MPS IVA
 

Status: Recruiting

Condition Summary: MPS IVA; Morquio Syndrome

 

Last Updated: 9 Aug 2013

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Last Updated: 3 Jan 2011

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