Mitochondrial Disorders

Common Name(s)

Mitochondrial Disorders, Mitochondrial diseases

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Mitochondrial Disorders" for support, advocacy or research.

Barth Syndrome Foundation

Our mission is saving lives through education, advances in treatment, and finding a cure for Barth syndrome.

http://www.barthsyndrome.org

Last Updated: 12 Apr 2014

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Isabella's Aviary Alliance, LLC

Isabella’s Aviary Alliance, LLC actively demonstrates, through Isabella’s passionate and loving care in breeding and raising baby parrots for other special needs children, the possibility for two hearts—bird and child—coming together and connecting in a way which infinitely brightens the lives of both.

http://www.isabellasaviary.com

Last Updated: 2 Aug 2013

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MitoAction

MitoAction's mission is to improve the quality of life for everyone affected by mitochondrial disease through support, education, outreach, and advocacy initiatives.

http://www.mitoaction.org/

Last Updated: 4 Mar 2013

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Muscular Dystrophy Association

MDA is the nonprofit health agency dedicated to curing muscular dystrophy, ALS and related diseases by funding worldwide research. The Association also provides comprehensive health care and support services, advocacy and education.

http://www.mdausa.org

Last Updated: 8 Mar 2010

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United Mitochondrial Disease Foundation

The United Mitochondrial Disease Foundation strives to promote research and education for the diagnosis, treatment and cures of mitochondrial disorders and to provide support to affected individuals and families.

http://www.umdf.org

Last Updated: 28 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Mitochondrial Disorders" for support, advocacy or research.

Barth Syndrome Foundation

Our mission is saving lives through education, advances in treatment, and finding a cure for Barth syndrome.

http://www.barthsyndrome.org

Last Updated: 12 Apr 2014

View Details
Isabella's Aviary Alliance, LLC

Isabella’s Aviary Alliance, LLC actively demonstrates, through Isabella’s passionate and loving care in breeding and raising baby parrots for other special needs children, the possibility for two hearts—bird and child—coming together and connecting in a way which infinitely brightens the lives of both.

http://www.isabellasaviary.com

Last Updated: 2 Aug 2013

View Details
MitoAction

MitoAction's mission is to improve the quality of life for everyone affected by mitochondrial disease through support, education, outreach, and advocacy initiatives.

http://www.mitoaction.org/

Last Updated: 4 Mar 2013

View Details
Logo
Muscular Dystrophy Association

MDA is the nonprofit health agency dedicated to curing muscular dystrophy, ALS and related diseases by funding worldwide research. The Association also provides comprehensive health care and support services, advocacy and education.

http://www.mdausa.org

Last Updated: 8 Mar 2010

View Details
United Mitochondrial Disease Foundation

The United Mitochondrial Disease Foundation strives to promote research and education for the diagnosis, treatment and cures of mitochondrial disorders and to provide support to affected individuals and families.

http://www.umdf.org

Last Updated: 28 Feb 2013

View Details

 

General Support Organizations

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General Resources

UMDF National Resource Guide

The UMDF Mitochondrial Resource Guide is available Online! It represents many hours of searching for the best information and resources to help you care for yourself and/or your family member affected by a mitochondrial disease.

Updated 29 Oct 2012

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2012 Conference Program

Barth Syndrome Foundation 2012 Conference Program

Updated 2 Nov 2012

Open Doc
Barth Syndrome Professional Healthcare Brochure

Important information regarding diagnosis and treatment of Barth syndrome.

Updated 12 Apr 2014

Open Doc
 
 
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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Mitochondrial Disorders" returned 43 free, full-text research articles on human participants. First 3 results:

Targeted exome sequencing for mitochondrial disorders reveals high genetic heterogeneity.
 

Author(s): Jeana T DaRe, Valeria Vasta, John Penn, Nguyen-Thao B Tran, Si Houn Hahn

Journal:

 

Mitochondrial disorders are difficult to diagnose due to extreme genetic and phenotypic heterogeneities.

Last Updated: 17 Jan 2014

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Prevalence of rare mitochondrial DNA mutations in mitochondrial disorders.
 

Author(s): Sylvie Bannwarth, Vincent Procaccio, Anne Sophie Lebre, Claude Jardel, Annabelle Chaussenot, Claire Hoarau, Hassani Maoulida, Nathanaël Charrier, Xiaowu Gai, Hongbo M Xie, Marc Ferre, Konstantina Fragaki, Gaëlle Hardy, Bénédicte Mousson de Camaret, Sandrine Marlin, Claire Marie Dhaenens, Abdelhamid Slama, Christophe Rocher, Jean Paul Bonnefont, Agnès Rötig, Nadia Aoutil, Mylène Gilleron, Valérie Desquiret-Dumas, Pascal Reynier, Jennifer Ceresuela, Laurence Jonard, Aurore Devos, Caroline Espil-Taris, Delphine Martinez, Pauline Gaignard, Kim-Hanh Le Quan Sang, Patrizia Amati-Bonneau, Marni J Falk, Catherine Florentz, Brigitte Chabrol, Isabelle Durand-Zaleski, Véronique Paquis-Flucklinger

Journal: J. Med. Genet.. 2013 Oct;50(10):704-14.

 

Mitochondrial DNA (mtDNA) diseases are rare disorders whose prevalence is estimated around 1 in 5000. Patients are usually tested only for deletions and for common mutations of mtDNA which account for 5-40% of cases, depending on the study. However, the prevalence of rare mtDNA mutations ...

Last Updated: 18 Sep 2013

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Mitochondrial mechanisms and neurological disorders.
 

Author(s): Andrea L Gropman

Journal: Neurotherapeutics. 2013 Apr;10(2):185.

 

Last Updated: 15 Apr 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Mitochondrial Disorders" returned 46 free, full-text review articles on human participants. First 3 results:

Drug development for rare mitochondrial disorders.
 

Author(s): Orest Hurko

Journal: Neurotherapeutics. 2013 Apr;10(2):286-306.

 

Currently, all treatment of mitochondrial disorders is performed with dietary supplements or by off-label use of drugs approved for other indications. The present challenge is translation of our collective knowledge of the molecular details underlying the pathophysiology of mitochondrial ...

Last Updated: 15 Apr 2013

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Review of clinical trials for mitochondrial disorders: 1997-2012.
 

Author(s): Douglas S Kerr

Journal: Neurotherapeutics. 2013 Apr;10(2):307-19.

 

Over the last 15 years, some 16 open and controlled clinical trials for potential treatments of mitochondrial diseases have been reported or are in progress, and are summarized and reviewed herein. These include trials of administering dichloroacetate (an activator of pyruvate dehydrogenase ...

Last Updated: 15 Apr 2013

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The elusive magic pill: finding effective therapies for mitochondrial disorders.
 

Author(s): Amy Goldstein, Lynne A Wolfe

Journal: Neurotherapeutics. 2013 Apr;10(2):320-8.

 

The incidence of mitochondrial diseases has been estimated at 11.5/100,000 (1:8500) worldwide. In the USA up to 4000 newborns annually are expected to develop a mitochondrial disease. More than 50 million adults in the USA also suffer from diseases in which primary or secondary mitochondrial ...

Last Updated: 15 Apr 2013

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Tissue Sample Study for Mitochondrial Disorders
 

Status: Recruiting

Condition Summary: Mitochondrial Disorders; Mitochondrial Disease; Melas; Kearns Sayer; NARP; MNGIE; LHON; Mitochondrial Depletion Syndrome; Leigh's Disease

 

Last Updated: 1 Mar 2013

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North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
 

Status: Recruiting

Condition Summary: Mitochondrial Disorders; Mitochondrial Genetic Disorders; Mitochondrial Diseases; Disorder of Mitochondrial Respiratory Chain Complexes; Deletion and Duplication of Mitochondrial DNA

 

Last Updated: 18 Nov 2013

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Anesthesia in Patients With Mitochondrial Disease
 

Status: Recruiting

Condition Summary: Mitochondrial Diseases

 

Last Updated: 7 Feb 2014

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