Migraine

Common Name(s)

Migraine

A migraine is a severe headache that can cause intense throbbing or a pulsing sensation in your head. Environmental and genetic factors may play a role in causing migraines. Migraine headaches often begin in childhood, adolescence or early adulthood and may consist of four stages, prodrome, aura, headache, and postdrome.

Prodrome may occur one or two days before a migraine and are subtle changes in food craving, activity, irritability, neck stiffness, depression, constipation, and uncontrollable yawning. Aura may occur before or during migraine headaches. Symptoms of aura may include vision loss, bright spots, and speech problems (apshasia). During the migraine attack symptoms may include throbbing pain in sides of your head, sensitivity to light, sound, and sometimes smells, nausea, vomiting, blurred vision, and lightheadedness. Postdrome is the last phase that occurs after a migraine attack where you may feel drained and washed out.

Migraine headache triggers may include, food, caffeinated and alcoholic drinks, stress, sensory stimuli, changes in wake-sleep pattern, physical factors, changes in the environment, hormonal changes in women, and medications. Risk factors may include family history, age, sex, and hormonal changes. Your doctor may diagnose your condition based on your medical history, symptoms and a physical and neurological examination. To rule out other possible causes for your pain your doctor may perform blood tests, computerized tomography (CT) scan, magnetic resonance imaging (MRI) and or a spinal tap (lumbar puncture). If you or someone you know suffers from migraines talk to your doctor to learn how to manage your condition.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Migraine" for support, advocacy or research.

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National Headache Foundation

The National Headache Foundation exists to enhance the healthcare of individuals with headache. It is a source of help to their families, physicians and allied healthcare professionals who treat them, and to the public. The NHF accomplishes its mission by providing educational and informational resources, supporting headache research, and advocating for the understanding of headache as a legitimate neurobiological disease.

Last Updated: 16 Mar 2015

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APS Foundation of America, Inc.

The APS Foundation of America, Inc. is dedicated to fostering and facilitating joint efforts in the areas of education, public awareness, research and patient services in an effective and ethical manner.

Last Updated: 12 Aug 2013

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Migraine" for support, advocacy or research.

Logo
National Headache Foundation

The National Headache Foundation exists to enhance the healthcare of individuals with headache. It is a source of help to their families, physicians and allied healthcare professionals who treat them, and to the public. The NHF accomplishes its mission by providing educational and informational resources, supporting headache research, and advocating for the understanding of headache as a legitimate neurobiological disease.

http://www.headaches.org

Last Updated: 16 Mar 2015

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APS Foundation of America, Inc.

The APS Foundation of America, Inc. is dedicated to fostering and facilitating joint efforts in the areas of education, public awareness, research and patient services in an effective and ethical manner.

http://www.apsfa.org

Last Updated: 12 Aug 2013

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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General Resources

Migraine Signs and Symptoms

A migraine is a throbbing or pulsating headache that is often one sided (unilateral) and associated with nausea; vomiting; sensitivity to light, sound, and smells; sleep disruption; and depression. Attacks are often recurrent and tend to become less

Updated 13 Nov 2012

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APS Foundation of America, Inc Fan Page

The APS Foundation of America, Inc. is the leading United States nonprofit health agency dedicated to bringing national awareness to Antiphospholipid Antibody Syndrome (APS).

Updated 13 Nov 2012

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Blogs

APS Friends & Support Forum

Are you looking for Support for Antiphospholipid Antibody Syndrome, APS, APLS, APLA, Hughes Syndrome, or Sticky Blood? Well you've come to the right place! This is an private forum for people who have Antiphospholipid Antibody Syndrome, friends, fam

Updated 13 Nov 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Migraine" returned 1977 free, full-text research articles on human participants. First 3 results:

Systemic diseases and other painful conditions in patients with temporomandibular disorders and migraine.
 

Author(s): Edwin Fernando Ruiz Contreras, Giovana Fernandes, Paula Cristina Jordani Ongaro, Leticia Bueno Campi, Daniela Aparecida Godoi Gonçalves

Journal:

 

Temporomandibular disorders (TMD) are a highly prevalent, painful musculoskeletal condition affecting the masticatory system, and are frequently associated with migraines (M) and other diseases. This study aimed to investigate the association between painful TMD and M with other painful ...

Last Updated: 31 Dec 1969

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Migraine improvement correlates with posterior cingulate cortical thickness reduction.
 

Author(s): Vanise C G Amaral, Gustavo Tukamoto, Tadeu Kubo, Ronir Raggio Luiz, Emerson Gasparetto, Maurice B Vincent

Journal: Arq Neuropsiquiatr. 2018 Mar;76(3):150-157.

 

Objective The main goal of this study was to correlate migraine improvement, after prophylactic therapy, with cortical thickness changes. Methods Cortical thickness maps were obtained with magnetic resonance imaging (MRI) from 19 patients with migraine before (first scan) and after ...

Last Updated: 31 Dec 1969

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Patterns of medicinal cannabis use, strain analysis, and substitution effect among patients with migraine, headache, arthritis, and chronic pain in a medicinal cannabis cohort.
 

Author(s): Eric P Baron, Philippe Lucas, Joshua Eades, Olivia Hogue

Journal:

 

Medicinal cannabis registries typically report pain as the most common reason for use. It would be clinically useful to identify patterns of cannabis treatment in migraine and headache, as compared to arthritis and chronic pain, and to analyze preferred cannabis strains, biochemical ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Migraine" returned 382 free, full-text review articles on human participants. First 3 results:

Migraine as a risk factor for primary open angle glaucoma: A systematic review and meta-analysis.
 

Author(s): Chang Xu, Jingjing Li, Zhi Li, Xiaochun Mao

Journal: Medicine (Baltimore). 2018 Jul;97(28):e11377.

 

Migraine is increasingly being reported as a risk factor for primary open angle glaucoma (POAG). However, studies aimed to investigate this association yielded conflicting results. To assess the consistency of the data on the topic, we performed a systematic review and meta-analysis. ...

Last Updated: 31 Dec 1969

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Transport of the pituitary adenylate cyclase-activating polypeptide across the blood-brain barrier: implications for migraine.
 

Author(s): Faisal Mohammad Amin, Henrik Winther Schytz

Journal:

 

Pituitary adenylate cyclase-activating polypeptide (PACAP) is widely distributed in the nervous system and is involved in migraine pathophysiology. Understanding the function of the blood-brain barrier (BBB) in relation to PACAP is important to the understand the mechanisms behind ...

Last Updated: 31 Dec 1969

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Electroacupuncture for migraine protocol for a systematic review of controlled trials.
 

Author(s): Hongmin Chu, Jihye Seo, Cheolhyun Kim, Yeonju Moon, Dae Gill Kang, Ho Sub Lee, Kang-Keyng Sung, Sangkwan Lee

Journal: Medicine (Baltimore). 2018 Apr;97(17):e9999.

 

A migraine is one of the primary headache disorders. Acupuncture has been widely used to treat migraine. Furthermore, electroacupuncture (EA) treatment has been also used to treat migraine. However, there has been no systematic review by assessing efficacy and safety of EA on migraine. ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study of Efficacy and Safety of AMG 334 in Adult Episodic Migraine Patients
 

Status: Recruiting

Condition Summary: Migraine

 

Last Updated: 16 Sep 2018

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Pain Processing in Adults With Migraines
 

Status: Recruiting

Condition Summary: Migraines

 

Last Updated: 12 Jul 2018

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A Study of Lasmiditan (LY573144) Over Four Migraine Attacks
 

Status: Not yet recruiting

Condition Summary: Migraine

 

Last Updated: 12 Sep 2018

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