Lymphoproliferative syndrome X-linked 1

Common Name(s)

Lymphoproliferative syndrome X-linked 1, X-Linked Lymphoproliferative Syndrome (XLP), Duncan's Disease

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lymphoproliferative syndrome X-linked 1" for support, advocacy or research.

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XLP Research Trust

The XLP Research Trust exists to (1) Promote and fund research into the cause, management, symptoms and cure for XLP (2) Provide a point of contact and support for those families affected by XLP (3) Raise the awareness of XLP amongst the medical profession and the general public

Last Updated: 17 Oct 2012

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lymphoproliferative syndrome X-linked 1" for support, advocacy or research.

Logo
XLP Research Trust

The XLP Research Trust exists to (1) Promote and fund research into the cause, management, symptoms and cure for XLP (2) Provide a point of contact and support for those families affected by XLP (3) Raise the awareness of XLP amongst the medical profession and the general public

http://www.xlpresearchtrust.org

Last Updated: 17 Oct 2012

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Lymphoproliferative syndrome X-linked 1" returned 2 free, full-text research articles on human participants. First 3 results:

Interleukin-21 overexpression dominates T cell response to Epstein-Barr virus in a fatal case of X-linked lymphoproliferative syndrome type 1.
 

Author(s): Consuelo Ortega, Orlando A Estévez, Silvia Fernández, Rocío Aguado, José M Rumbao, Teresa Gonzalez, Juan L Pérez-Navero, Manuel Santamaría

Journal: Clin. Vaccine Immunol.. 2013 May;20(5):765-71.

 

Interleukin-21 (IL-21) is a cytokine whose actions are closely related to B cell differentiation into plasma cells as well as to CD8(+) cytolytic T cell effector and memory generation, influencing the T lymphocyte response to different viruses. X-linked lymphoproliferative syndrome ...

Last Updated: 29 Apr 2013

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Clinical similarities and differences of patients with X-linked lymphoproliferative syndrome type 1 (XLP-1/SAP deficiency) versus type 2 (XLP-2/XIAP deficiency).
 

Author(s): Jana Pachlopnik Schmid, Danielle Canioni, Despina Moshous, Fabien Touzot, Nizar Mahlaoui, Fabian Hauck, Hirokazu Kanegane, Eduardo Lopez-Granados, Ester Mejstrikova, Isabelle Pellier, Lionel Galicier, Claire Galambrun, Vincent Barlogis, Pierre Bordigoni, Alain Fourmaintraux, Mohamed Hamidou, Alain Dabadie, Françoise Le Deist, Filomeen Haerynck, Marie Ouachée-Chardin, Pierre Rohrlich, Jean-Louis Stephan, Christelle Lenoir, Stéphanie Rigaud, Nathalie Lambert, Michèle Milili, Claudin Schiff, Helen Chapel, Capucine Picard, Geneviève de Saint Basile, Stéphane Blanche, Alain Fischer, Sylvain Latour

Journal: Blood. 2011 Feb;117(5):1522-9.

 

X-linked lymphoproliferative syndromes (XLP) are primary immunodeficiencies characterized by a particular vulnerability toward Epstein-Barr virus infection, frequently resulting in hemophagocytic lymphohistiocytosis (HLH). XLP type 1 (XLP-1) is caused by mutations in the gene SH2D1A ...

Last Updated: 4 Feb 2011

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Lymphoproliferative syndrome X-linked 1" returned 0 free, full-text review articles on human participants.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

T Cell Depletion for Recipients of HLA Haploidentical Related Donor Stem Cell Grafts
 

Status: Recruiting

Condition Summary: Acute Lymphoblastic Leukemia; Non Hodgkins Lymphoma; Myelodysplastic Syndrome; Acute Myeloid Leukemia; Chronic Myelogenous Leukemia; Hemophagocytic Lymphohistiocytosis (HLH); Familial Hemophagocytic Lymphohistiocytosis (FLH); Viral-associated Hemophagocytic Syndrome (VAHS); X-linked Lymphoproliferative Disease (XLP)

 

Last Updated: 18 Nov 2014

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Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies
 

Status: Recruiting

Condition Summary: SCID; Omenn's Syndrome; Reticular Dysgenesis; Wiskott-Aldrich Syndrome; Bare Lymphocyte Syndrome; Common Variable Immunodeficiency; Chronic Granulomatous Disease; CD40 Ligand Deficiency; Hyper IgM Syndrome; X-linked Lymphoproliferative Disease; Hemophagocytic Lymphohistiocytosis; Griscelli Syndrome; Chediak-Higashi Syndrome; Langerhan's Cell Histiocytosis

 

Last Updated: 22 Apr 2015

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Unrelated Hematopoietic Stem Cell Transplantation(HSCT) for Genetic Diseases of Blood Cells
 

Status: Recruiting

Condition Summary: Sickle Cell Disease; Thalassemia; Anemia; Granuloma; Wiskott-Aldrich Syndrome; Chediak Higashi Syndrome; Osteopetrosis; Neutropenia; Thrombocytopenia; Hurler Disease; Niemann-Pick Disease; Fucosidosis

 

Last Updated: 22 Jun 2011

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