Kawasaki Disease

Common Name(s)

Kawasaki Disease, Acute febrile mucocutaneous lymph node syndrome, Kawasaki syndrome

Kawasaki disease, also known as mucocutaneous lymph node syndrome, is a serious condition that is characterized by the inflammation of the blood vessels in the body. The condition typically affects children under the age of five, primarily those of Asian and Pacific Island descent. However, the disease can also develop in individuals of different ages and ethnicities.

Symptoms of this condition generally come in stages. The early symptoms may include a high fever lasting more than five days, blood shot eyes, red cracked lips, swollen strawberry red colored tongue, and rashes on the chest and genital area. Later symptoms may include peeling of the skin on the hands and feet, joint pain, abdominal pain, diarrhea, and vomiting.

At this time, there is not an exact test to determine if someone is experiencing Kawasaki disease. After taking a health history, in addition to other tests to exclude other conditions, a doctor can make a formal diagnosis. Unfortunately, the official cause for this condition is unknown. The disease itself is usually manageable, but without treatment can cause very serious heart conditions for the affected individual. Therefore, if you or someone you know is experiencing the symptoms of Kawasaki disease, speak to your doctor immediately to discuss the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Kawasaki Disease" for support, advocacy or research.

Kids with Heart National Association for Children's Heart Disorders

Our organization was formed in 1985 with the main mission of providing support, information, resources, and education for the families of the children living with congenital heart defects and to promote public awareness of the issues that these families live with on a day to day basis.

Last Updated: 4 May 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Kawasaki Disease" for support, advocacy or research.

Kids with Heart National Association for Children's Heart Disorders

Our organization was formed in 1985 with the main mission of providing support, information, resources, and education for the families of the children living with congenital heart defects and to promote public awareness of the issues that these families live with on a day to day basis.

http://www.kidswithheart.org

Last Updated: 4 May 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Kawasaki Disease" returned 744 free, full-text research articles on human participants. First 3 results:

[Changes in 25-hydroxyvitamin D3 level and its significance in children with Kawasaki disease].
 

Author(s): Yuan-Da Zhang, Rong-Min Li, Chao-Yu Ji, Xiao-Long Zhang, Yu Zhang, Qing-Wei Dong, Lei Ma

Journal: Zhongguo Dang Dai Er Ke Za Zhi. 2016 Mar;18(3):211-4.

 

To investigate the changes in the serum level of 25-hydroxyvitamin D3 [25-(OH)D3] and its significance in children with Kawasaki disease (KD).

Last Updated: 15 Mar 2016

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Urinary Colorimetric Sensor Array and Algorithm to Distinguish Kawasaki Disease from Other Febrile Illnesses.
 

Author(s): Zhen Li, Zhou Tan, Shiying Hao, Bo Jin, Xiaohong Deng, Guang Hu, Xiaodan Liu, Jie Zhang, Hua Jin, Min Huang, John T Kanegaye, Adriana H Tremoulet, Jane C Burns, Jianmin Wu, Harvey J Cohen, Xuefeng B Ling,

Journal:

 

Kawasaki disease (KD) is an acute pediatric vasculitis of infants and young children with unknown etiology and no specific laboratory-based test to identify. A specific molecular diagnostic test is urgently needed to support the clinical decision of proper medical intervention, preventing ...

Last Updated: 10 Feb 2016

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Cardiopulmonary Function, Exercise Capacity, and Echocardiography Finding of Pediatric Patients With Kawasaki Disease: An Observational Study.
 

Author(s): Sheng-Hui Tuan, Min-Hui Li, Miao-Ju Hsu, Yun-Jeng Tsai, Yin-Han Chen, Tin-Yun Liao, Ko-Long Lin

Journal: Medicine (Baltimore). 2016 Jan;95(2):e2444.

 

Coronary artery (CA) abnormalities influence exercise capacity (EC) of patients with Kawasaki disease (KD), and Z-score of CA is a well established method for detecting CA aneurysm. We studied the influence of KD on cardiopulmonary function and EC; meanwhile we analyzed echocardiographic ...

Last Updated: 15 Jan 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Kawasaki Disease" returned 52 free, full-text review articles on human participants. First 3 results:

[Renal artery injury caused by Kawasaki disease].
 

Author(s): Zhi-Jian Wang, Mei-Hua Zhu, Li Zhang, Jun-Chu Chen, Li-Ling Zhu, Min Liang, Yun Peng

Journal: Zhongguo Dang Dai Er Ke Za Zhi. 2016 Jan;18(1):29-33.

 

To investigate renal artery injury caused by Kawasaki disease (KD).

Last Updated: 19 Jan 2016

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Recent Advances in Kawasaki Disease.
 

Author(s): Kyu Yeun Kim, Dong Soo Kim

Journal: Yonsei Med. J.. 2016 Jan;57(1):15-21.

 

Kawasaki disease (KD) is characterized with acute systemic vasculitis, occurs predominantly in children between 6 months to 5 years of age. Patients with this disease recover well and the disease is self-limited in most cases. Since it can lead to devastating cardiovascular complications, ...

Last Updated: 3 Dec 2015

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Peripheral Endothelial (Dys)Function, Arterial Stiffness and Carotid Intima-Media Thickness in Patients after Kawasaki Disease: A Systematic Review and Meta-Analyses.
 

Author(s): Sanne M Dietz, Carline E A Tacke, Barbara A Hutten, Taco W Kuijpers

Journal:

 

Kawasaki disease (KD) is a systemic pediatric vasculitis. Its main complication is the development of coronary arterial aneurysms (CAA), causing an increased risk for ischemia and myocardial infarction. It is unclear whether KD patients, apart from the presence of CAA, have an increased ...

Last Updated: 11 Jul 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Etanercept in Kawasaki Disease
 

Status: Recruiting

Condition Summary: Mucocutaneous Lymph Node Syndrome; Kawasaki Disease

 

Last Updated: 10 Dec 2015

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Anakinra and Kawasaki Disease
 

Status: Recruiting

Condition Summary: Kawasaki Disease; Children

 

Last Updated: 8 Dec 2015

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Different Doses of IVIG for Kawasaki Disease
 

Status: Recruiting

Condition Summary: Kawasaki Disease

 

Last Updated: 31 Jan 2016

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