Kawasaki Disease

Common Name(s)

Kawasaki Disease, Acute febrile mucocutaneous lymph node syndrome, Kawasaki syndrome

Kawasaki syndrome is a condition that involves inflammation of the blood vessels.  It is typically diagnosed in young children, but older children and adults can also develop this condition.   Kawasaki syndrome is usually accompanied by a fever that lasts at least 5 days. Other classic symptoms may include red eyes, lips, and mouth; rash; swollen and red hands and feet; and swollen lymph nodes. Kawasaki syndrome occurs most often in people of Asian and Pacific Island descent.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Kawasaki Disease" for support, advocacy or research.

Kids with Heart National Association for Children's Heart Disorders

Our organization was formed in 1985 with the main mission of providing support, information, resources, and education for the families of the children living with congenital heart defects and to promote public awareness of the issues that these families live with on a day to day basis.

http://www.kidswithheart.org

Last Updated: 30 Oct 2012

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Kawasaki Disease" for support, advocacy or research.

Kids with Heart National Association for Children's Heart Disorders

Our organization was formed in 1985 with the main mission of providing support, information, resources, and education for the families of the children living with congenital heart defects and to promote public awareness of the issues that these families live with on a day to day basis.

http://www.kidswithheart.org

Last Updated: 30 Oct 2012

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Kawasaki Disease" returned 543 free, full-text research articles on human participants. First 3 results:

[Origin and importance of the Latin American Kawasaki Disease Network (REKAMLATINA)].
 

Author(s): Antonio González-Mata, Rolando Ulloa-Gutierrez, José Brea del Castillo, Guillermo Soza, Adriana H Tremoulet

Journal: Rev Chilena Infectol. 2013 Aug;30(4):402-4.

 

Kawasaki disease is the leading cause of acquired cardiac disease in children. Although the epidemiology of the disease has been well described in Japan, other Asian countries, Europe, Australia and North America, the epidemiology and disease burden in Latin American children is unknown. ...

Last Updated: 19 Nov 2013

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Mortality among Japanese with a history of Kawasaki disease: results at the end of 2009.
 

Author(s): Yosikazu Nakamura, Eiko Aso, Mayumi Yashiro, Satoshi Tsuboi, Takao Kojo, Yasuko Aoyama, Kazuhiko Kotani, Ritei Uehara, Hiroshi Yanagawa

Journal: J Epidemiol. 2013 ;23(6):429-34.

 

The long-term outcomes of Kawasaki disease (KD) are unknown.

Last Updated: 5 Nov 2013

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[Association of single nucleotide polymorphism in TGFBR2 gene with Kawasaki disease and coronary artery lesions].
 

Author(s): Cui-Ping Shi, Hong-Yan Zhang

Journal: Zhongguo Dang Dai Er Ke Za Zhi. 2013 Sep;15(9):767-70.

 

To examine the single nucleotide polymorphism (SNP) (rs1495592) in transforming growth factor-beta receptor 2 (TGFBR2) gene in children, and to investigate its association with Kawasaki disease (KD) and coronary artery lesions (CALs).

Last Updated: 16 Sep 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Kawasaki Disease" returned 38 free, full-text review articles on human participants. First 3 results:

Management of Kawasaki disease.
 

Author(s): D Eleftheriou, M Levin, D Shingadia, R Tulloh, N J Klein, P A Brogan

Journal: Arch. Dis. Child.. 2014 Jan;99(1):74-83.

 

Kawasaki disease (KD) is an acute self-limiting inflammatory disorder, associated with vasculitis, affecting predominantly medium-sized arteries, particularly the coronary arteries. In developed countries KD is the commonest cause of acquired heart disease in childhood. The aetiology ...

Last Updated: 16 Dec 2013

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Kawasaki disease--the importance of prompt recognition and early referral.
 

Author(s): Daniel Golshevsky, Michael Cheung, David Burgner

Journal: Aust Fam Physician. 2013 Jul;42(7):473-6.

 

Kawasaki disease is an acute, febrile vasculitis of childhood that affects medium sized arteries, particularly the coronary arteries. Consequently, it is the leading cause of paediatric-acquired heart disease in developed countries. It is important to have a high index of suspicion ...

Last Updated: 4 Jul 2013

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Coronary artery sequel of Kawasaki disease in adulthood, a concern for internists and cardiologists.
 

Author(s): Anggoro B Hartopo, Budi Y Setianto

Journal: Acta Med Indones. 2013 Jan;45(1):69-75.

 

Young adults suffered from acute cardiac event, such as acute coronary syndrome, ischemic-associated arrhythmia and sudden death, are frequently encountered without known etiology and significant risk factors. Coronary vasculitis due to Kawasaki disease contributes to be a risk factor ...

Last Updated: 15 Apr 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Etanercept in Kawasaki Disease
 

Status: Recruiting

Condition Summary: Mucocutaneous Lymph Node Syndrome; Kawasaki Disease

 

Last Updated: 11 Nov 2013

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Prevalence and Early Markers of Atherosclerosis in Adults With a History of Kawasaki Disease
 

Status: Recruiting

Condition Summary: Kawasaki Disease

 

Last Updated: 22 Sep 2011

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Trial of Atorvastatin on the Persistent Coronary Aneurysm in Children With Kawasaki Disease
 

Status: Recruiting

Condition Summary: Kawasaki Disease; Aneurysm, Coronary

 

Last Updated: 14 Apr 2014

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