Inflammatory bowel disease

Common Name(s)

Inflammatory bowel disease, IBD

Inflammatory bowel disease (IBD) is the chronic redness and swelling (inflammation) of all or part of the digestive tract, which includes the esophagus, stomach, small intestine, and large intestine. The exact cause of the inflammation in IBD is not known, but a person’s immune system and genetic makeup are both thought to play a role. Risk factors for developing IBD includes older age, Caucasian (white) ethnic background, cigarette smoking, and using certain medications.

The two main types of IBD are ulcerative colitis and Crohn’s disease. Ulcerative colitis is a condition that causes inflammation and sores (ulcers) on the inside lining of the large intestine. Crohn’s disease causes inflammation that spreads deep into the affected tissue and usually affects the large intestine, the small intestine, or both. Symptoms of IBD vary and depend on the location and severity of the inflammation. Symptoms may include diarrhea, fever and fatigue, abdominal pain and cramping, blood in the stool, reduced appetite, and unintended weight loss.

To diagnose IBD, a physician will first rule out other possible causes of the symptoms. To confirm a diagnosis of IBD, your doctor may order a blood test to look for low red blood cells (anemia), a procedure that uses a small camera to examines your digestive tract for signs of IBD (endoscopy or colonoscopy), and imaging tests (X-rays, CT, or MRI) to look for evidence of IBD. Treatment includes the use of medications that reduces the immune system’s response and decreases the inflammation in the digestive tract. In severe cases, surgery may be needed. Although this condition is serious, affected individuals can live a normal life with proper treatment and care. If you or your child has been diagnosed with IBD, talk with your doctor about the current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Inflammatory bowel disease" for support, advocacy or research.

Crohn's & Colitis Foundation of America, Inc.

CCFA's mission is to cure Crohn's disease and ulcerative colitis and to improve the quality of life of children and adults affected by these diseases.

Last Updated: 8 Apr 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Inflammatory bowel disease" for support, advocacy or research.

Crohn's & Colitis Foundation of America, Inc.

CCFA's mission is to cure Crohn's disease and ulcerative colitis and to improve the quality of life of children and adults affected by these diseases.

http://www.ccfa.org

Last Updated: 8 Apr 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Inflammatory bowel disease" returned 2693 free, full-text research articles on human participants. First 3 results:

Effectiveness and safety of adalimumab to treat outpatient ulcerative colitis: A real-life multicenter, observational study in primary inflammatory bowel disease centers.
 

Author(s): Antonio Tursi, Walter Elisei, Roberto Faggiani, Leonardo Allegretta, Nicola Della Valle, Giacomo Forti, Marilisa Franceschi, Antonio Ferronato, Sara Gallina, Tiziana Larussa, Francesco Luzza, Roberto Lorenzetti, Giammarco Mocci, Antonio Penna, Stefano Rodino', Ladislava Sebkova, Antonio de Medici, Giuseppe Pranzo, Cristina Ricciardelli, Giuseppina Grasso, Stefano Scorza, Costantino Zampaletta, Marcello Picchio

Journal: Medicine (Baltimore). 2018 Aug;97(34):e11897.

 

Adalimumab (ADA) was approved in Italy for the treatment of ulcerative colitis (UC) unresponsive to standard treatments in 2014, but no data from real life are currently available. The aim of the present study was to assess the real-life efficacy and safety of ADA in managing UC outpatients ...

Last Updated: 31 Dec 1969

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SERUM INFLIXIMAB MEASUREMENT IN INFLAMMATORY BOWEL DISEASE PATIENTS IN REMISSION: A COMPARATIVE ANALYSIS OF TWO DIFFERENT METHODS IN A MULTICENTRIC BRAZILIAN COHORT.
 

Author(s): Fábio Vieira Teixeira, Ligia Yukie Sassaki, Rogerio Saad-Hossne, Julio Pinheiro Baima, Daniéla Oliveira Magro, Claudio Saddy Rodrigues Coy, Paulo Gustavo Kotze

Journal: Arq Gastroenterol. ;55(2):192-197.

 

Infliximab (IFX) therapeutic drug monitoring is an important tool to guide therapeutic decision in inflammatory bowel disease patients. Currently, there are two methods to measure trough levels of IFX, ELISA assays or rapid tests. Despite that the ELISA assay is the most used method ...

Last Updated: 31 Dec 1969

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FREQUENCY OF OPHTHALMOLOGICAL POSTERIOR SEGMENT FINDINGS IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE.
 

Author(s): Luis Filipe Nakayama, Vinicius Campos Bergamo, Marina Lourenço de Conti, Lívia Costa, Nilva Simeren Bueno de Moraes, Orlando Ambrogini

Journal: Arq Gastroenterol. ;55(2):188-191.

 

Inflammatory bowel disease is a systemic inflammatory disease classified as Crohn disease or ulcerative colitis. It could present extra intestinal findings, such as fever, weight loss, arthralgia, mucocutaneous lesions, hepatic, renal and ophthalmological involvement. Among ophthalmological ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Inflammatory bowel disease" returned 1005 free, full-text review articles on human participants. First 3 results:

Trichuris suis ova therapy in inflammatory bowel disease: A meta-analysis.
 

Author(s): Xing Huang, Li-Rong Zeng, Feng-Song Chen, Jing-Ping Zhu, Meng-Hua Zhu

Journal: Medicine (Baltimore). 2018 Aug;97(34):e12087.

 

In recent years, Trichuris suis ova (TSO) therapy in inflammatory bowel disease (IBD) has attracted much attention. However, efficacy and safety of TSO therapy are still not well described. The aim of the study was to perform a meta-analysis to assess the effectiveness of TSO therapy in IBD.

Last Updated: 31 Dec 1969

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Colonic lesion characterization in inflammatory bowel disease: A systematic review and meta-analysis.
 

Author(s): Richard Lord, Nicholas E Burr, Noor Mohammed, Venkataraman Subramanian

Journal: World J. Gastroenterol.. 2018 Mar;24(10):1167-1180.

 

To perform a systematic review and meta-analysis for the diagnostic accuracy of lesion characterization in colonic inflammatory bowel disease (IBD), using optical imaging techniques, including virtual chromoendoscopy (VCE), dye-based chromoendoscopy (DBC), magnification endoscopy ...

Last Updated: 31 Dec 1969

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Inflammatory bowel disease registries for collection of patient iron parameters in Europe.
 

Author(s): Jonas Halfvarson, Fraser Cummings, Olof Grip, Guillaume Savoye

Journal: World J. Gastroenterol.. 2018 Mar;24(10):1063-1071.

 

Iron deficiency without anemia and iron deficiency anemia are common and frequently overlooked complications of inflammatory bowel disease. Despite the frequency and impact of iron deficiency in inflammatory bowel disease, there are gaps in our understanding about its incidence, prevalence ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Inflammatory Bowel Disease Registry in Daegu-Gyeongbuk
 

Status: Recruiting

Condition Summary: Idiopathic Chronic Inflammatory Bowel Disease

 

Last Updated: 19 Jul 2018

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Last Updated: 13 Sep 2017

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Rheumatological Manifestations in Inflammatory Bowel Diseases
 

Status: Not yet recruiting

Condition Summary: Inflammatory Bowel Diseases

 

Last Updated: 1 Apr 2018

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