Infertility

Common Name(s)

Infertility

Infertility is defined as the inability to become pregnant, despite having frequent, unprotected sex for at least a year (or six months under certain circumstances). Infertility may also refer to the state of a woman not being able to carry a pregnancy to full term (resulting in miscarriage). About 10-15% of couples are infertile in the United States. Infertility may be due to a single cause in either you or your partner or a combination of factors. About one third of the time the cause of infertility only involves the male. About one third of the time, the cause of infertility only involves the female. In the remaining one third of the time, the cause involves both male and female or no cause can be found. The causes of male infertility include abnormal sperm production or function, problems with the delivery of sperm, overexposure to certain environmental factors, or damage related to cancer. Causes of female infertility include ovulation disorders, uterine or cervical abnormalities, fallopian tube damage or blockage, endometriosis, pelvic adhesions, thyroid problems, cancer treatment, or other conditions or medications. Risk factors for male and female infertility include advanced age (for women over 35, for men over 40), tobacco use, alcohol use, being overweight or underweight, not enough exercise, or too much strenuous, intense exercise (particularly for women). Diagnosis is made through a number of different tests. Testing and trial treatments may extend over several months. The good news is that there are many safe and effective therapies for overcoming infertility. And due to research, treatment options continue to improve the chances a couple will become pregnant. Talk with your obstetrician or midwife if you are having trouble becoming pregnant. He or she will most likely suggest you see an infertility specialist possibly at an infertility center. Support organizations are also good resources for support and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Infertility" for support, advocacy or research.

FORCE: Facing Our Risk of Cancer Empowered

FORCE is a national nonprofit dedicated to fighting hereditary breast and ovarian cancer. With 50 outreach groups throughout the U.S., and international affiliates, FORCE programs provide support, education, advocacy, awareness and research specific to hereditary cancers. Our programs serve anyone with a BRCA mutation or a family history of cancer. FORCE was founded on the principle that no one should have to face hereditary breast and ovarian cancer alone.

Last Updated: 5 May 2014

View Details
HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

View Details
Logo
RESOLVE, INC.: The National Infertility Association

RESOLVE: The National Infertility Association, established in 1974, is a non-profit organization with the only established, nationwide network mandated to promote reproductive health and to ensure equal access to all family building options for men and women experiencing infertility or other reproductive disorders. RESOLVE improves the lives of women and men living with infertility by providing community to these women and men, connecting them with others who can help, empowering them to find resolution and giving voice to their demands for access to all family building options.

Last Updated: 20 Feb 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Infertility" for support, advocacy or research.

FORCE: Facing Our Risk of Cancer Empowered

FORCE is a national nonprofit dedicated to fighting hereditary breast and ovarian cancer. With 50 outreach groups throughout the U.S., and international affiliates, FORCE programs provide support, education, advocacy, awareness and research specific to hereditary cancers. Our programs serve anyone with a BRCA mutation or a family history of cancer. FORCE was founded on the principle that no one should have to face hereditary breast and ovarian cancer alone.

http://www.facingourrisk.org

Last Updated: 5 May 2014

View Details
HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

View Details
Logo
RESOLVE, INC.: The National Infertility Association

RESOLVE: The National Infertility Association, established in 1974, is a non-profit organization with the only established, nationwide network mandated to promote reproductive health and to ensure equal access to all family building options for men and women experiencing infertility or other reproductive disorders. RESOLVE improves the lives of women and men living with infertility by providing community to these women and men, connecting them with others who can help, empowering them to find resolution and giving voice to their demands for access to all family building options.

http://www.resolve.org

Last Updated: 20 Feb 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Infertility" returned 1282 free, full-text research articles on human participants. First 3 results:

Case report of a pituitary thyrotropin-secreting macroadenoma with Hashimoto thyroiditis and infertility.
 

Author(s): Jiaqi Li, Jianwei Li, Shu Jiang, Ruichao Yu, Yerong Yu

Journal: Medicine (Baltimore). 2018 Jan;97(1):e9546.

 

Thyrotropin-secreting adenoma (TSHoma) is rare, diagnosis and treatment are often delayed if the condition coexists with Hashimoto thyroiditis. The enlarged pituitary adenoma may eventually induce panhypopituitarism, infertility, or the compression of optic nerves and optic chiasma.

Last Updated: 31 Dec 1969

Go To URL
The effectiveness of Korean medicine treatment in male patients with infertility: a study protocol for a prospective observational pilot study.
 

Author(s): Kwan-Ii Kim, Junyoung Jo

Journal: Medicine (Baltimore). 2018 Jan;97(4):e9696.

 

Male factor subfertility has increasingly been considered the cause of infertility in couples. Many men with male infertility have sperm problems such as oligozoospermia, asthenozoospermia, or teratozoospermia. Because abnormal semen parameters are idiopathic to some extent, no standard ...

Last Updated: 31 Dec 1969

Go To URL
Microbiota-based analysis reveals specific bacterial traits and a novel strategy for the diagnosis of infectious infertility.
 

Author(s): Simon Graspeuntner, Michael K Bohlmann, Kathrin Gillmann, Runa Speer, Sven Kuenzel, Heike Mark, Friederike Hoellen, Reinhard Lettau, Georg Griesinger, Inke R König, John F Baines, Jan Rupp

Journal:

 

Tubal factor infertility (TFI) accounts for more than 30% of the cases of female infertility and mostly resides from an inflammatory process triggered by an infection. Clinical appearances largely differ, and very often infections are not recognized or remain completely asymptomatic ...

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Infertility" returned 285 free, full-text review articles on human participants. First 3 results:

Human papillomavirus in semen and the risk for male infertility: a systematic review and meta-analysis.
 

Author(s): Zhangyan Lyu, Xiaoshuang Feng, Ni Li, Wei Zhao, Luopei Wei, Yuheng Chen, Wenjing Yang, Hongxia Ma, Bing Yao, Kai Zhang, Zhibin Hu, Hongbing Shen, Dong Hang, Min Dai

Journal:

 

Human papillomavirus (HPV) is one of the most prevalent sexually transmitted viruses. Despite the increasing evidence of HPV prevalence in semen, the worldwide distribution of HPV types in semen and risk for male infertility remain inconclusive.

Last Updated: 31 Dec 1969

Go To URL
Acupuncture is not as effective as infertility treatment in women with PCOS.
 

Author(s): Liangzhi Xu, Xiaoyong Qiao

Journal: Evid Based Med. 2017 12;22(6):229-230.

 

Last Updated: 31 Dec 1969

Go To URL
The diagnosis of male infertility: an analysis of the evidence to support the development of global WHO guidance-challenges and future research opportunities.
 

Author(s): Christopher L R Barratt, Lars Björndahl, Christopher J De Jonge, Dolores J Lamb, Francisco Osorio Martini, Robert McLachlan, Robert D Oates, Sheryl van der Poel, Bianca St John, Mark Sigman, Rebecca Sokol, Herman Tournaye

Journal: Hum. Reprod. Update. 2017 Nov;23(6):660-680.

 

Herein, we describe the consensus guideline methodology, summarize the evidence-based recommendations we provided to the World Health Organization (WHO) for their consideration in the development of global guidance and present a narrative review of the diagnosis of male infertility ...

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Uterine Transplant in Absolute Uterine Infertility (AUIF)
 

Status: Not yet recruiting

Condition Summary: Female Infertility

 

Last Updated: 27 Apr 2016

Go to URL
Analysis of TU-LESS by 3D Laparoscopy in the Treatment of Infertility
 

Status: Not yet recruiting

Condition Summary: Infertility, Female

 

Last Updated: 26 Oct 2016

Go to URL
ICSI Versus Conventional IVF in Couples With Non-severe Male Infertility
 

Status: Not yet recruiting

Condition Summary: Male Infertility

 

Last Updated: 5 Apr 2018

Go to URL