Hypoparathyroidism

Common Name(s)

Hypoparathyroidism

Hypoparathyroidism is is an endocrine disorder in which the parathyroid glands in the neck do not produce enough parathyroid hormone (PTH). Common signs and symptoms include abdominal pain, brittle nails, cataracts, dry hair and skin, muscle cramps, tetany, pain in the face, legs, and feet, seizures, tingling sensation, and weakened tooth enamel (in children). It may be caused by injury to the parathyroid glands (e.g., during surgery). Other causes, include low blood magnesium levels, a side effect of radioactive iodine treatment for hyperthyroidism, metabolic alkalosis, DiGeorge syndrome, and type I polyglandular autoimmune syndrome. The goal of treatment is to restore the calcium and mineral balance in the body.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hypoparathyroidism" for support, advocacy or research.

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Hypoparathyroidism UK

Working to improve the lives of people with hypoparathyroidism and other parathyroid conditions.

Last Updated: 1 Apr 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hypoparathyroidism" for support, advocacy or research.

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Hypoparathyroidism UK

Working to improve the lives of people with hypoparathyroidism and other parathyroid conditions.

http://www.hpth.org.uk

Last Updated: 1 Apr 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hypoparathyroidism" returned 307 free, full-text research articles on human participants. First 3 results:

The impact of different surgical procedures on hypoparathyroidism after thyroidectomy: A population-based study.
 

Author(s): Kuan-Chen Chen, Usman Iqbal, Phung-Anh Nguyen, Chung-Huei Hsu, Chen-Ling Huang, Yi-Hsin Elsa Hsu, Suleman Atique, Md Mohaimenul Islam, Yu-Chuan Jack Li, Wen-Shan Jian

Journal: Medicine (Baltimore). 2017 Oct;96(43):e8245.

 

The main objective of this study is to investigate the outcome between surgical procedures and the risk of development of hypoparathyroidism followed by surgical procedure in patients with thyroid disorders.We analyzed the data acquired from Taiwan's Bureau of National Health Insurance ...

Last Updated: 31 Dec 1969

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Risk factors of hypoparathyroidism following total thyroidectomy with central lymph node dissection.
 

Author(s): Anping Su, Bin Wang, Yanping Gong, Rixiang Gong, Zhihui Li, Jingqiang Zhu

Journal: Medicine (Baltimore). 2017 Sep;96(39):e8162.

 

The risk factors of hypoparathyroidism after total thyroidectomy (TT) with central lymph node dissection (CND) have not been completely defined. The aim of the study was to evaluate the risk factors of hypoparathyroidism after the surgery.We retrospectively reviewed our patients who ...

Last Updated: 31 Dec 1969

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Unusual Proliferative Glomerulonephritis in a Patient Diagnosed to Have Hypoparathyroidism, Sensorineural Deafness, and Renal Dysplasia (HDR) Syndrome with a Novel Mutation in the GATA3 Gene.
 

Author(s): Michitsugu Kamezaki, Tetsuro Kusaba, Takaomi Adachi, Noriyuki Yamashita, Mayumi Nakata, Noriyoshi Ota, Yayoi Shiotsu, Mami Ishida, Takeshi Usui, Keiichi Tamagaki

Journal: Intern. Med.. 2017 ;56(11):1393-1397.

 

Hypoparathyroidism, sensorineural deafness, and renal dysplasia (HDR) syndrome is a rare autosomal dominant disease caused by GATA3 mutations. Although several cases with variable renal features have been reported, the presence of histological changes within the glomeruli in adult ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hypoparathyroidism" returned 17 free, full-text review articles on human participants. First 3 results:

[Risk factors' analysis of transient and permanent hypoparathyroidism after thyroidectomy].
 

Author(s): G Cocchiara, M Cajozzo, S Fazzotta, V D Palumbo, G Geraci, C Maione, S Buscemi, G Romano, F Fatica, G Spinelli, S Ficarella, A Maffongelli, F Caternicchia, A I Lo Monte

Journal: Clin Ter. ;168(4):e271-e277.

 

This review evaluates those main risk factors that can affect patients undergoing thyroidectomy, to reach a better pre- and post-operative management of transient and permanent hypoparathyroidism.

Last Updated: 31 Dec 1969

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Epidemiology and Diagnosis of Hypoparathyroidism.
 

Author(s): Bart L Clarke, Edward M Brown, Michael T Collins, Harald Jüppner, Peter Lakatos, Michael A Levine, Michael M Mannstadt, John P Bilezikian, Anatoly F Romanischen, Rajesh V Thakker

Journal: J. Clin. Endocrinol. Metab.. 2016 Jun;101(6):2284-99.

 

Hypoparathyroidism is a disorder characterized by hypocalcemia due to insufficient secretion of PTH. Pseudohypoparathyroidism is a less common disorder due to target organ resistance to PTH. This report summarizes the results of the findings and recommendations of the Working Group ...

Last Updated: 31 Dec 1969

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Management of Hypoparathyroidism: Present and Future.
 

Author(s): John P Bilezikian, Maria Luisa Brandi, Natalie E Cusano, Michael Mannstadt, Lars Rejnmark, René Rizzoli, Mishaela R Rubin, Karen K Winer, Uri A Liberman, John T Potts

Journal: J. Clin. Endocrinol. Metab.. 2016 Jun;101(6):2313-24.

 

Conventional management of hypoparathyroidism has focused upon maintaining the serum calcium with oral calcium and active vitamin D, often requiring high doses and giving rise to concerns about long-term consequences including renal and brain calcifications. Replacement therapy with ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Survey on Epidemiology of Hypoparathyroidism in France
 

Status: Recruiting

Condition Summary: Hypoparathyroidism

 

Last Updated: 7 Dec 2017

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Steroids in the Postoperative Transient Hypoparathyroidism Total Thyroidectomy
 

Status: Recruiting

Condition Summary: Transient Hypoparathyroidism

 

Last Updated: 4 Apr 2016

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