Hyperkalemic Periodic Paralysis Type 1

Common Name(s)

Hyperkalemic Periodic Paralysis Type 1

The 2 dominantly inherited, clinically similar types of episodic flaccid generalized weakness, HOKPP and HYPP, are distinguished by the changes in serum potassium levels during paralytic attacks. An important clinical difference between the 2 entities is represented by the triggers of attacks of weakness, e.g., HYPP can be provoked by oral potassium administration, whereas this is a remedy for HOKPP. Concurrence of myotonia is found in HYPP but usually not in HOKPP patients ({19:Jurkat-Rott et al., 2000}). {20:Jurkatt-Rott and Lehmann-Horn (2007)} provided a review of the clinical features, pathogenesis, and therapeutic options for HYPP.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hyperkalemic Periodic Paralysis Type 1" for support, advocacy or research.

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Scientific Literature

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Lamotrigine as Treatment of Myotonia
 

Status: Recruiting

Condition Summary: Dystrophia Myotonica Type 1; Myotonia Congenita; Paramyotonia Congenita; Hyperkalemic Periodic Paralysis; Potassium-Aggravated Myotonia

 

Last Updated: 4 Jun 2014

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