Hereditary pancreatitis

Common Name(s)

Hereditary pancreatitis

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hereditary pancreatitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hereditary pancreatitis" returned 45 free, full-text research articles on human participants. First 3 results:

Robust autoactivation, chymotrypsin C independence and diminished secretion define a subset of hereditary pancreatitis-associated cationic trypsinogen mutants.
 

Author(s): Andrea Geisz, Péter Hegyi, Miklós Sahin-Tóth

Journal: FEBS J.. 2013 Jun;280(12):2888-99.

 

Mutations in human cationic trypsinogen cause hereditary pancreatitis by altering its proteolytic regulation of activation and degradation by chymotrypsin C (CTRC). CTRC stimulates trypsinogen autoactivation by processing the activation peptide to a shorter form, but also promotes ...

Last Updated: 6 Jun 2013

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Whole exome sequencing identifies multiple, complex etiologies in an idiopathic hereditary pancreatitis kindred.
 

Author(s): Jessica LaRusch, M Michael Barmada, Shiela Solomon, David C Whitcomb

Journal:

 

Hereditary pancreatitis is the early onset form of chronic pancreatitis that is carried in an autosomal dominant pattern with variable penetrance. While 80% of hereditary pancreatitis has been shown to be due to a single mutation in the trypsinogen gene PRSS1, a number of hereditary ...

Last Updated: 10 May 2012

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Increased activation of hereditary pancreatitis-associated human cationic trypsinogen mutants in presence of chymotrypsin C.
 

Author(s): András Szabó, Miklós Sahin-Tóth

Journal: J. Biol. Chem.. 2012 Jun;287(24):20701-10.

 

Mutations in human cationic trypsinogen (PRSS1) cause autosomal dominant hereditary pancreatitis. Increased intrapancreatic autoactivation of trypsinogen mutants has been hypothesized to initiate the disease. Autoactivation of cationic trypsinogen is proteolytically regulated by chymotrypsin ...

Last Updated: 11 Jun 2012

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hereditary pancreatitis" returned 8 free, full-text review articles on human participants. First 3 results:

Hereditary chronic pancreatitis.
 

Author(s): Jonas Rosendahl, Hans Bödeker, Joachim Mössner, Niels Teich

Journal:

 

Hereditary chronic pancreatitis (HCP) is a very rare form of early onset chronic pancreatitis. With the exception of the young age at diagnosis and a slower progression, the clinical course, morphological features and laboratory findings of HCP do not differ from those of patients ...

Last Updated: 18 Jan 2007

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Biochemical models of hereditary pancreatitis.
 

Author(s): Miklós Sahin-Tóth

Journal: Endocrinol. Metab. Clin. North Am.. 2006 Jun;35(2):303-12, ix.

 

The past decade has witnessed remarkable progress in the genetics of chronic pancreatitis. Despite these accomplishments, the understanding of the molecular mechanisms through which PRSS1 and SPINK1 mutations cause chronic pancreatitis has remained sketchy. Pancreatitis-associated ...

Last Updated: 24 Apr 2006

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[Hereditary pancreatitis].
 

Author(s): Sung Koo Lee

Journal: Korean J Gastroenterol. 2005 Nov;46(5):358-67.

 

The first family of hereditary pancreatitis was described in 1952. The mode of inheritance is autosomal dominant trait with an 80% of penetrance rate. Although hereditary pancreatitis is rare, this disorder has provided valuable insights in understanding the pathophysiology of pancreatitis ...

Last Updated: 22 Nov 2005

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Pancreatic Cancer Early Detection Program
 

Status: Recruiting

Condition Summary: Pancreatic Cancer; Pancreas Cancer; Pancreatic Adenocarcinoma; Familial Pancreatic Cancer; BRCA 1/2; HNPCC; Lynch Syndrome; Hereditary Pancreatitis; FAMMM; Familial Atypical Multiple Mole Melanoma; Peutz Jeghers Syndrome

 

Last Updated: 30 Jul 2014

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Pancreatic Cancer Screening of High-Risk Residents of Arkansas
 

Status: Not yet recruiting

Condition Summary: Pancreatic Neoplasms; Peutz-Jegher's Syndrome; BRCA1 Gene Mutation; BRCA2 Gene Mutation; Ataxia Telangiectasia; Familial Atypical Mole-Malignant Melanoma Syndrome; Colorectal Neoplasms, Hereditary Nonpolyposis; Hereditary Pancreatitis

 

Last Updated: 3 Dec 2014

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Quality Control Study of MR Based Screening of Individual With Increased Risk for Pancreas Cancer.
 

Status: Recruiting

Condition Summary: Hereditary Pancreatitis; Hereditary Pancreatic Cancer

 

Last Updated: 4 Mar 2014

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