Hemochromatosis type 2

Common Name(s)

Hemochromatosis type 2

Hemochromatosis type 2 is a disease in which too much iron builds up in the body.  This extra iron is toxic to the body and can damage the organs. Type 2 hemochromatosis is a juvenile-onset disorder. Iron accumulation begins early in life, and symptoms may begin to appear in childhood. Hemochromatosis is inherited in an autosomal recessive manner. It is caused by a mutation in the HAMP or HFE2 gene.

Hemochromatosis may be aquired or inherited. Hereditary hemochromatosis is classified by type depending on the age of onset and other factors such as genetic cause and mode of inheritance. To learn more about other types click on the disease names below:

Hemochromatosis type 1
Hemochromatosis type 3
Hemochromatosis type 4

There is also a neonatal form of hemochromatosis:

Neonatal hemochromatosis

 

Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hemochromatosis type 2" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hemochromatosis type 2" returned 7 free, full-text research articles on human participants. First 3 results:

Re: "hemochromatosis gene (HFE) polymorphisms and risk of type 2 diabetes mellitus: a meta-analysis".
 

Author(s): Dongfeng Zhang, Xiubo Jiang, Yili Wu, Wenjie Jiang, Zengchang Pang

Journal: Am. J. Epidemiol.. 2013 Feb;177(4):372-3.

 

Last Updated: 8 Feb 2013

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Hemochromatosis gene (HFE) polymorphisms and risk of type 2 diabetes mellitus: a meta-analysis.
 

Author(s): Ying Rong, Wei Bao, Shuang Rong, Min Fang, Di Wang, Ping Yao, Frank B Hu, Liegang Liu

Journal: Am. J. Epidemiol.. 2012 Sep;176(6):461-72.

 

The hemochromatosis gene (HFE) has been involved in the etiology of type 2 diabetes mellitus and investigated in numerous epidemiologic studies. The current meta-analysis was conducted to evaluate the gene-disease association in relevant studies. Electronic literature search was performed ...

Last Updated: 24 Sep 2012

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Lack of association of C282Y and H63D mutations in the hemochromatosis (HFE) gene with diabetes mellitus type 2 in a case-control study of women in Brazil.
 

Author(s): K B Gomes, M G Carvalho, F F Coelho, I F Rodrigues, A L Soares, D A GuimarĂ£es, A P Fernandes

Journal:

 

Hereditary hemochromatosis is one of the most common autosomal recessive diseases; it is characterized by excess absorption of iron. Clinically, the major challenge is to diagnose increased iron deposition before irreversible tissue damage has occurred. C282Y and H63D are the main ...

Last Updated: 30 Oct 2009

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Reviews from the PubMed Database

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The terms "Hemochromatosis type 2" returned 0 free, full-text review articles on human participants.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Analysis of the Modulation of Serum Hepcidin Level in Response to Iron Oral Intake: Potential Interest for the Differential Diagnosis Between Ferroportin Disease and Dysmetabolic Hepatosiderosis.
 

Status: Recruiting

Condition Summary: Hemochromatosis, Type 4; Ferroportin Disease; Dysmetabolic Hepatosiderosis; Diagnosis

 

Last Updated: 11 Sep 2014

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