Hypoplastic left heart syndrome 2

Common Name(s)

Hypoplastic left heart syndrome 2

Hypoplastic left heart syndrome results from defective development of the aorta proximal to the entrance of the ductus arteriosus and hypoplasia of the left ventricle and mitral valve. As a result of the abnormal circulation, the ductus arteriosus and foramen ovale are patent and the right atrium, right ventricle, and pulmonary artery are enlarged ({1:Brekke, 1953}). For a discussion of genetic heterogeneity of hypoplastic left heart syndrome, see HLHS1 ({241550}).
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hypoplastic left heart syndrome 2" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hypoplastic left heart syndrome 2" returned 3 free, full-text research articles on human participants. First 3 results:

Prenatal diagnosis of atrial restriction in hypoplastic left heart syndrome is associated with decreased 2-year survival.
 

Author(s): Alexander Lowenthal, Alaina K Kipps, Michael M Brook, Jeffery Meadows, Anthony Azakie, Anita J Moon-Grady

Journal: Prenat. Diagn.. 2012 May;32(5):485-90.

 

To compare the course of hypoplastic left heart syndrome (HLHS) patients diagnosed prenatally with any degree of atrial restriction with those without evidence of atrial restriction.

Last Updated: 9 May 2012

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Novel insights into RV adaptation and function in hypoplastic left heart syndrome between the first 2 stages of surgical palliation.
 

Author(s): Nee Scze Khoo, Jeffrey F Smallhorn, Sachie Kaneko, Kimberly Myers, Shelby Kutty, Edythe B Tham

Journal: JACC Cardiovasc Imaging. 2011 Feb;4(2):128-37.

 

This study sought to examine the changes in ventricular function of hypoplastic left heart syndrome (HLHS) between the first 2 stages of surgical palliation.

Last Updated: 18 Feb 2011

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Early survival of infants weighing 2.5 kilograms or less undergoing first-stage reconstruction for hypoplastic left heart syndrome.
 

Author(s): S Weinstein, J W Gaynor, N D Bridges, G Wernovsky, L M Montenegro, R I Godinez, T L Spray

Journal: Circulation. 1999 Nov;100(19 Suppl):II167-70.

 

Results of staged palliation for hypoplastic left heart syndrome (HLHS) have improved in recent years; however, certain risk factors have been associated with decreased survival rates.

Last Updated: 15 Dec 1999

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hypoplastic left heart syndrome 2" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Cardiac Progenitor Cell Infusion to Treat Univentricular Heart Disease (PERSEUS)
 

Status: Recruiting

Condition Summary: Hypoplastic Left Heart Syndrome; Single Right Ventricle; Single Left Ventricle

 

Last Updated: 14 Oct 2014

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