Graves' Disease

Common Name(s)

Graves' Disease, Graves Disease

Graves' disease is an autoimmune disorder that leads to overactivity of the thyroid gland (hyperthyroidism). It is caused by an abnormal immune system response that causes the thyroid gland to produce too much thyroid hormones. Graves disease is the most common cause of hyperthyroidism and occurs most often in women over age 20. However, the disorder may occur at any age and may affect males as well.  Treatment may include radioiodine therapy, antithyroid drugs, and/or thyroid surgery.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Graves' Disease" for support, advocacy or research.

Graves' Disease and Thyroid Foundation

The purpose and mission of the Graves' Disease & Thyroid Foundation is to provide support and educational services for patients and family members impacted by Graves' disease, thyroid eye disease, Hashimoto's thyroiditis, and other thyroid-related disorders. Services are delivered via phone/e-mail/U.S. Mail, social media, online forums, local support groups, and national educational events.

http://www.gdatf.org

Last Updated: 12 Mar 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Graves' Disease" for support, advocacy or research.

Graves' Disease and Thyroid Foundation

The purpose and mission of the Graves' Disease & Thyroid Foundation is to provide support and educational services for patients and family members impacted by Graves' disease, thyroid eye disease, Hashimoto's thyroiditis, and other thyroid-related disorders. Services are delivered via phone/e-mail/U.S. Mail, social media, online forums, local support groups, and national educational events.

http://www.gdatf.org

Last Updated: 12 Mar 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Graves' Disease" returned 561 free, full-text research articles on human participants. First 3 results:

Palmar vitiligo associated with Graves' disease.
 

Author(s): Yosuke Sasaki, Mitsuyo Kinjo, Rita Lynn McGill, Hitoshi Miyasato

Journal: Intern. Med.. 2013 ;52(17):2001-2.

 

Last Updated: 2 Sep 2013

Go To URL
Expression of estrogen and progesterone receptors and Ki-67 antigen in Graves' disease and nodular goiter.
 

Author(s): Pawel Domoslawski, Marzena Podhorska-Okolow, Bartosz Pula, Tadeusz Lukienczuk, Piotr Dziegiel

Journal: Folia Histochem. Cytobiol.. 2013 ;51(2):135-40.

 

Graves' Disease (GD) is an autoimmune disease with higher prevalence in women than in men. The aim of the study was to correlate the expression of estrogen (ER) and progesterone receptors (PR) as well as Ki- 67 cell proliferation index in thyroid sections of GD and nodular goiter ...

Last Updated: 2 Aug 2013

Go To URL
A high frequency of circulating th22 and th17 cells in patients with new onset graves' disease.
 

Author(s): Di Peng, Bingchuan Xu, Ye Wang, Hui Guo, Yanfang Jiang

Journal:

 

T-helper (Th) 22 and Th17 cells are involved in the pathogenesis of autoimmune diseases. However, their roles in the pathogenesis of Graves'disease (GD) are unclear. This study is aimed at examining the frequency of peripheral blood Th22, Th17, and Th1 cells and the levels of plasma ...

Last Updated: 22 Jul 2013

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Graves' Disease" returned 34 free, full-text review articles on human participants. First 3 results:

[Selenium in Graves' disease].
 

Author(s): Jadwiga Kryczyk, Paweł Zagrodzki

Journal:

 

The aim of this study was to present the current state of knowledge of the role of selenium in Graves' disease. Recently, in the pathogenesis and course of this autoimmune disease, more attention has been paid to the relationship between oxidative stress and the antioxidant system, ...

Last Updated: 11 Jun 2013

Go To URL
Mechanisms in endocrinology. Role of emotional stress in the pathophysiology of Graves' disease.
 

Author(s): Géraldine Falgarone, Hassan M Heshmati, Régis Cohen, Gérard Reach

Journal:

 

The role of stress in the pathophysiology of Graves' disease is suggested by several clinical observations, by recent advances in immunology and by better understanding of autoimmune diseases which provides new insights into potential effects of stress hormones on T helper cell imbalance ...

Last Updated: 11 Dec 2012

Go To URL
Autoimmunity and Graves' disease.
 

Author(s): R S Bahn

Journal: Clin. Pharmacol. Ther.. 2012 Apr;91(4):577-9.

 

Current treatment options for Graves' hyperthyroidism and the related ophthalmopathy (GO) are not uniformly effective and carry with them potentially serious side effects. As a result, efforts have been focused on the development of novel therapies. Progress has been made, particularly ...

Last Updated: 21 Mar 2012

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Shared Decision Making in Graves Disease - Graves Disease (GD) Choice
 

Status: Recruiting

Condition Summary: Graves' Disease; Thyroid Disease; Hyperthyroidism

 

Last Updated: 4 Apr 2014

Go to URL
Comparative Study of Different I-131 Doses in Graves' Disease
 

Status: Recruiting

Condition Summary: Graves' Disease

 

Last Updated: 14 Apr 2014

Go to URL
Radioactive Iodide Therapy for Pediatric Graves' Disease
 

Status: Recruiting

Condition Summary: Graves' Disease

 

Last Updated: 7 Feb 2014

Go to URL