Glycine N-methyltransferase deficiency

Common Name(s)

Glycine N-methyltransferase deficiency

Description for this condition is not yet available.
 

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Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Glycine N-methyltransferase deficiency" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Glycine N-methyltransferase deficiency" returned 2 free, full-text research articles on human participants. First 3 results:

Glycine N-methyltransferase deficiency affects Niemann-Pick type C2 protein stability and regulates hepatic cholesterol homeostasis.
 

Author(s): Yi-Jen Liao, Tzu-Lang Chen, Tzong-Shyuan Lee, Hsiang-An Wang, Chung-Kwe Wang, Li-Ying Liao, Ren-Shyan Liu, Shiu-Feng Huang, Yi-Ming Arthur Chen

Journal:

 

Nonalcoholic fatty liver disease (NAFLD) is associated with the development of metabolic syndromes and hepatocellular carcinoma (HCC). Cholesterol accumulation is related to NAFLD, whereas its detailed mechanism is not fully understood. Previously, we reported that glycine N-methyltransferase ...

Last Updated: 25 May 2012

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A glycine N-methyltransferase knockout mouse model for humans with deficiency of this enzyme.
 

Author(s): Zigmund Luka, Antonieta Capdevila, José M Mato, C Wagner

Journal: Transgenic Res.. 2006 Jun;15(3):393-7.

 

Three human cases having mutations in the glycine N-methyltransferase (GNMT) gene have been reported. This enzyme transfers a methyl group from S-adenosylmethionine (SAM) to glycine to form S-adenosylhomocysteine (SAH) and N-methylglycine (sarcosine) and is believed to be involved ...

Last Updated: 16 Jun 2006

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Reviews from the PubMed Database

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The terms "Glycine N-methyltransferase deficiency" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.