Fragile XE Syndrome

Common Name(s)

Fragile XE Syndrome, FRAXE

Fragile XE syndrome is a genetic condition associated with mild to borderline intellectual disabilities (IQ = 50-85) with physical features differing from person to person. The characteristic features are learning difficulties, often a consequence of communication problems (speech delay, poor writing skills), and overactivity. Fragile XE syndrome is caused by a specific type of change (mutation) called a trinucleotide repeat expansion that occurs on chromosome X. The repeating trinucleotide in Fragile XE syndrome is CCG. When the number of CCG repeats is over 200, people typically have the signs and symptoms seen in Fragile XE syndrome.

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Advocacy and Support Organizations Health Questions Recommended Apps Scientific Literature Symptoms, Diagnosis, and Treatment Clinical Trial Information
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Fragile XE Syndrome" for support, advocacy or research.

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Fragile XE Syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
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Recommended Apps

Privately answer questions about your health. Let resources, you select, come to you

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

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Relief is when you and the right researcher find each other

Finding the right clinical trial for Fragile XE Syndrome can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Fragile XE Syndrome" returned 0 free, full-text research articles on human participants.

No free, full-text research articles on human participants are available at this time. Please click this link to visit the PubMed website for results on "Fragile XE Syndrome".

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Fragile XE Syndrome" returned 0 free, full-text review articles on human participants.

No free, full-text review articles on human participants are available at this time. Please click this link to visit the PubMed website for results on "Fragile XE Syndrome".

 
 
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Symptoms, Diagnosis, and Treatment

This information is provided by Genetics Home Reference.
https://ghr.nlm.nih.gov/condition/fragile-xe-syndrome
https://ghr.nlm.nih.gov/gene/AFF2
https://ghr.nlm.nih.gov/condition/fragile-x-syndrome
https://ghr.nlm.nih.gov/condition/fragile-x-associated-tremor-ataxia-syndrome
https://ghr.nlm.nih.gov/condition/kindler-syndrome
https://ghr.nlm.nih.gov/condition/grange-syndrome
https://ghr.nlm.nih.gov/gene/FMR1
https://ghr.nlm.nih.gov/gene/FERMT1
https://ghr.nlm.nih.gov/condition/fragile-x-associated-primary-ovarian-insufficiency
https://ghr.nlm.nih.gov/gene/AFF1
https://ghr.nlm.nih.gov/gene/PKP1
https://ghr.nlm.nih.gov/gene/TSPAN7
https://ghr.nlm.nih.gov/gene/ADAMTS2
https://ghr.nlm.nih.gov/gene/DIP2B
https://ghr.nlm.nih.gov/gene/FKBP10
https://ghr.nlm.nih.gov/condition/laryngo-onycho-cutaneous-syndrome
https://ghr.nlm.nih.gov/gene/COL4A1
https://ghr.nlm.nih.gov/condition/gnathodiaphyseal-dysplasia
https://ghr.nlm.nih.gov/condition/pachyonychia-congenita
https://ghr.nlm.nih.gov/gene/COL5A2
Full Results at Genetics Home Reference: 1682 matches

There are currently no related results available in GeneReviews.

This information is provided by Genetic Testing Registry.
http://www.ncbi.nlm.nih.gov/gtr/conditions/C0751157
 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.

According to ClinicalTrials.gov there are currently 0 additional "open" studies for "Fragile XE Syndrome" (open studies are recruiting volunteers) and 0 "Fragile XE Syndrome" studies with "all" status. Visit ClinicalTrials.gov now to view them. Or alternatively, consider TrialsFinder for assistance:
TrialsFinder Branding Graphics
Relief is when you and the right researcher find each other
Finding the right clinical trial for Fragile XE Syndrome can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.
Learn More