Fatal Familial Insomnia
Common Name(s)
Fatal Familial Insomnia
Advocacy and Support Organizations
Condition Specific Organizations
Following organizations serve the condition "Fatal Familial Insomnia" for support, advocacy or research.
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Advocacy and Support Organizations
Condition Specific Organizations
Following organizations serve the condition "Fatal Familial Insomnia" for support, advocacy or research.
Recommended Apps
Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.
Finding the right clinical trial for Fatal Familial Insomnia can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.
Scientific Literature
Articles from the PubMed Database
Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Fatal Familial Insomnia" returned 19 free, full-text research articles on human participants.
First 3 results:
Journal: Medicine (Baltimore). 2017 Dec;96(49):e8951.
Fatal familial insomnia (FFI) linked to a D178N/129M haplotype mutation in the PRNP gene is the most common genetic prion disease in the Han Chinese population. Here, we describe a Han Chinese patient with FFI who exhibited agrypnia excitata and obstructive apnea.
Journal:
To explore clinical, histopathological and genetic features of a case with fatal familial insomnia (FFI) and review the related literatures. A middle-aged woman who complained of "insomnia for 9 months and psychosis for 3 months" was suspicious of FFI. The clinical features of the ...
Journal: Prion. 2015 ;9(3):228-35.
Familial fatal insomnia (FFI) is fatal disorder characterized by damage to select thalamic nuclei, together with progressive insomnia and dysautonomia. In subjects carrying the D178N prion protein (PRNP) mutation, distinct phenotypes can be observed, depending on the methionine (Met) ...
To view other free, full-text articles on human participants, please click on the link below.
Reviews from the PubMed Database
Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Fatal Familial Insomnia" returned 2 free, full-text review articles on human participants.
First 3 results:
Journal:
Fatal familial insomnia (FFI) is a rare autosomal dominant disease caused by the PRNP D178N/129 M mutation. Routine brain CT and MRI usually reveal non-specific features. We report a patient with FFI presenting with diffuse abnormal signals on MRI, later confirmed as combined with ...
Journal:
Fatal familial insomnia (FFI) is a genetically transmitted neurodegenerative prion disease that incurs great suffering and has neither a treatment nor a cure. The clinical literature is devoid of management plans (other than palliative). Part 1 of this article reviews the sparse literature ...
To view other free, full-text review articles on human participants, please click on the link below.
Symptoms, Diagnosis, and Treatment
https://ghr.nlm.nih.gov/condition/early-onset-myopathy-with-fatal-cardiomyopathy
https://ghr.nlm.nih.gov/gene/PRNP
https://ghr.nlm.nih.gov/condition/familial-hypertrophic-cardiomyopathy
https://ghr.nlm.nih.gov/gene/COA6
https://ghr.nlm.nih.gov/condition/familial-hypobetalipoproteinemia
https://ghr.nlm.nih.gov/condition/familial-hyperaldosteronism
https://ghr.nlm.nih.gov/condition/familial-candidiasis
https://ghr.nlm.nih.gov/condition/familial-cylindromatosis
https://ghr.nlm.nih.gov/condition/familial-erythrocytosis
https://ghr.nlm.nih.gov/condition/familial-dysautonomia
https://ghr.nlm.nih.gov/condition/familial-porencephaly
https://ghr.nlm.nih.gov/condition/congenital-afibrinogenemia
https://ghr.nlm.nih.gov/condition/multiple-pterygium-syndrome
https://ghr.nlm.nih.gov/condition/arts-syndrome
https://ghr.nlm.nih.gov/gene/TUFM
https://ghr.nlm.nih.gov/gene/NDUFAF3
https://ghr.nlm.nih.gov/condition/familial-hemiplegic-migraine
https://ghr.nlm.nih.gov/condition/familial-hemophagocytic-lymphohistiocytosis
https://ghr.nlm.nih.gov/condition/familial-hdl-deficiency
Clinical Trial Information This information is provided by ClinicalTrials.gov
Condition Summary: Ataxia; Dystonia; Parkinson's Disease; Amyotrophic Lateral Sclerosis; Corticobasal Degeneration; Multiple System Atrophy; Alzheimer's Disease; Lewy Body Dementia; Parkinson Disease-Dementia; Dentatorubral-pallidoluysian Atrophy; Creutzfeldt-Jakob Disease and Fatal Familial Insomnia; Fragile X-associated Tremor/Ataxia Syndrome; Krabbe's Disease; Niemann-Pick Disease, Type C; Neuronal Ceroid Lipofuscinosis

Finding the right clinical trial for Fatal Familial Insomnia can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.