Fallot Tetralogy

Common Name(s)

Fallot Tetralogy

Tetralogy of Fallot is a complex congenital heart defect characterized by a large ventricular septal defect (hole between the right and left ventricles), pulmonary stenosis (narrowing of the valve and artery that connect the heart with the lungs), an overriding aorta (the aorta - the artery that carries oxygen-rich blood to the body - is shifted over the right ventricle and ventricular septal defect, instead of coming out only from the left ventricle), and right ventricular hypertrophy (the muscle of the right ventricle is thicker than usual). Tetralogy of Fallot causes low oxygen levels in the blood, which can lead to cyanosis (a bluish-purple color to the skin). The cause of this condition is unknown. Treatment involves surgery to repair the heart defects. Sometimes more than one surgery is needed.  
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Fallot Tetralogy" for support, advocacy or research.

Saving Little Hearts

Saving Little Hearts is dedicated to helping children with congenital heart defects and their families by providing emotional assistance and educational information primarily through the distribution of Care Packages.

Last Updated: 15 Mar 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Fallot Tetralogy" for support, advocacy or research.

Saving Little Hearts

Saving Little Hearts is dedicated to helping children with congenital heart defects and their families by providing emotional assistance and educational information primarily through the distribution of Care Packages.

http://www.savinglittlehearts.com

Last Updated: 15 Mar 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Fallot Tetralogy" returned 449 free, full-text research articles on human participants. First 3 results:

Pulmonary arterial hypertension associated with tetralogy of Fallot.
 

Author(s): Jun Yasuhara, Hiroyuki Yamagishi

Journal: Int Heart J. 2015 ;56 Suppl():S17-21.

 

Pulmonary arterial hypertension (PAH) is a common postoperative complication in patients with congenital heart disease (CHD). Although the recent clinical classification of pulmonary hypertension divided PAH associated with CHD (PAH-CHD) into several subclasses, the anatomical and ...

Last Updated: 19 Mar 2015

Go To URL
Risk factors for late right ventricular systolic dysfunction in pediatric patients with repaired tetralogy of Fallot.
 

Author(s): Qiang Ji, Yunqing Mei, Xisheng Wang, Jing Feng, Wenjun Ding

Journal: Int Heart J. 2015 ;56(1):80-5.

 

To evaluate independent risk factors for late right ventricular systolic dysfunction after correction of Tetralogy of Fallot (TOF) in a single-centre, retrospective and observational clinical trial.Patients less than 3 years of age who underwent correction of TOF and subsequently ...

Last Updated: 6 Mar 2015

Go To URL
Assessment of left ventricular preload by cardiac magnetic resonance imaging predicts exercise capacity in adult operated tetralogy of Fallot: a retrospective study.
 

Author(s): Jonathan Yap, Ju Le Tan, Thu Thao Le, Fei Gao, Liang Zhong, Reginald Liew, Swee Yaw Tan, Ru San Tan

Journal:

 

The optimal timing of pulmonary homograft valve replacement (PVR) is uncertain. Cardiopulmonary exercise testing (CPET) and cardiac magnetic resonance (CMR) are often used to guide the clinical decision for PVR in operated tetralogy of Fallot (TOF) patients with significant pulmonary ...

Last Updated: 25 Sep 2014

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Fallot Tetralogy" returned 16 free, full-text review articles on human participants. First 3 results:

Is there a role for mechanical valve prostheses in pulmonary valve replacement late after tetralogy of Fallot repair?
 

Author(s): Jonathan Raihan Abbas, J Andreas Hoschtitzky

Journal: Interact Cardiovasc Thorac Surg. 2014 May;18(5):661-6.

 

A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was: What is the role of mechanical valve prostheses in pulmonary valve replacement late after tetralogy of Fallot (TOF) repair? Altogether more than 30 papers were found ...

Last Updated: 23 Apr 2014

Go To URL
Tetralogy of fallot with dextrocardia and situs inversus in a 7-year-old boy.
 

Author(s): Michael Dilorenzo, Samuel Weinstein, Rajesh Shenoy

Journal: Tex Heart Inst J. 2013 ;40(4):481-3.

 

Tetralogy of Fallot is one of the most frequently diagnosed congenital cardiac abnormalities; however, its association with dextrocardia and situs inversus is reported only rarely. We report a case of these findings in a 7-year-old boy, describe the patient's postoperative course, ...

Last Updated: 1 Oct 2013

Go To URL
Which is the best tissue valve used in the pulmonary position, late after previous repair of tetralogy of Fallot?
 

Author(s): Jonathan Raihan Abbas, J Andreas Hoschtitzky

Journal: Interact Cardiovasc Thorac Surg. 2013 Nov;17(5):854-60.

 

A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was: which is the best tissue valve for use in the pulmonary position, late after previous repair of tetralogy of Fallot? Altogether 141 papers were found using the reported ...

Last Updated: 23 Oct 2013

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Right and Left Ventricle Remodeling Predictors After Pulmonary Valve Replacement in Patients With Repaired Tetralogy of Fallot
 

Status: Recruiting

Condition Summary: Tetralogy of Fallot With Pulmonary Stenosis

 

Last Updated: 8 Jul 2014

Go to URL
Tetralogy of Fallot Seed Grant
 

Status: Recruiting

Condition Summary: Pulmonary Regurgitation After Repair of Tetralogy of Fallot

 

Last Updated: 23 Jul 2008

Go to URL
Biomodel in Tetralogy of Fallot
 

Status: Recruiting

Condition Summary: Tetralogy of Fallot

 

Last Updated: 19 Dec 2005

Go to URL