Ewing's Sarcoma

Common Name(s)

Ewing's Sarcoma, Ewing Sarcoma, Ewings Sarcoma

Ewing's sarcoma is a malignant (cancerous) bone tumor that affects children. It can occur any time during childhood and young adulthood, but usually develops during puberty, when bones are growing rapidly. The tumor may arise anywhere in the body, usually in the long bones of the arms and legs, the pelvis, or the chest. It may also develop in the skull or the flat bones of the trunk. There are few symptoms. The most common is pain and occasionally swelling at the site of the tumor. Fever may also be present. The tumor often spreads (metastasis) to the lungs and other bones. The cause of Ewing's sarcoma is unknown.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ewing's Sarcoma" for support, advocacy or research.

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Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

Last Updated: 20 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ewing's Sarcoma" for support, advocacy or research.

Logo
Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

http://sarcomaalliance.org

Last Updated: 20 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ewing's Sarcoma" returned 305 free, full-text research articles on human participants. First 3 results:

Ewing's sarcoma arising from the adrenal gland in a young male: a case report.
 

Author(s): Muhammad Nauman Zahir, Tayyaba Zehra Ansari, Tariq Moatter, Wasim Memon, Shahid Pervez

Journal:

 

Ewing's sarcoma uncommonly arises from extraosseous soft tissue or parenchymal organs. Primary adrenal Ewing's Sarcoma, although very rare, is extremely aggressive and commonly fatal.

Last Updated: 19 Dec 2013

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[Retroperitoneal extraskeletal Ewing's sarcoma].
 

Author(s): Si Hyung Lee, Byung Ik Jang

Journal: Korean J Gastroenterol. 2013 Oct;62(4):253-5.

 

Last Updated: 10 Dec 2013

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Characterization and drug resistance patterns of Ewing's sarcoma family tumor cell lines.
 

Author(s): William A May, Rita S Grigoryan, Nino Keshelava, Daniel J Cabral, Laura L Christensen, Jasmine Jenabi, Lingyun Ji, Timothy J Triche, Elizabeth R Lawlor, C Patrick Reynolds

Journal:

 

Despite intensive treatment with chemotherapy, radiotherapy and surgery, over 70% of patients with metastatic Ewing's Sarcoma Family of Tumors (EFT) will die of their disease. We hypothesize that properly characterized laboratory models reflecting the drug resistance of clinical tumors ...

Last Updated: 6 Dec 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ewing's Sarcoma" returned 25 free, full-text review articles on human participants. First 3 results:

Primary Ewing's sarcoma/primitive neuroectodermal tumor of the urogenital tract in children.
 

Author(s): Hong-cheng Song, Ning Sun, Wei-ping Zhang, Cheng-ru Huang

Journal: Chin. Med. J.. 2012 Mar;125(5):932-6.

 

Primary Ewing's sarcoma/primitive neuroectodermal tumor (ES/PNET) of urogenital tract is a rare condition with non-specific clinical presentations, which can make it difficult to diagnose. In this study, we summarize the clinical presentation, pathological features, therapeutic strategies, ...

Last Updated: 11 Apr 2012

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Promiscuous partnerships in Ewing's sarcoma.
 

Author(s): Savita Sankar, Stephen L Lessnick

Journal: Cancer Genet. 2011 Jul;204(7):351-65.

 

Ewing's sarcoma is a highly aggressive bone and soft tissue tumor of children and young adults. At the molecular genetic level Ewing's sarcoma is characterized by a balanced reciprocal translocation, t(11;22)(q24;q12), which encodes an oncogenic fusion protein and transcription factor ...

Last Updated: 29 Aug 2011

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Review of therapeutic strategies for osteosarcoma, chondrosarcoma, and Ewing's sarcoma.
 

Author(s): Xing Dai, Wei Ma, Xijing He, Rajiv Kumar Jha

Journal: Med. Sci. Monit.. 2011 Aug;17(8):RA177-190.

 

The most prevalent forms of bone cancer are osteosarcoma, chondrosarcoma, and Ewing's sarcoma. Although chemotherapy and radiotherapy have replaced traditional surgical treatments, survival rates have undergone only marginal improvements. Current knowledge of the molecular pathways ...

Last Updated: 1 Aug 2011

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Whole-Body Radiation Therapy, Systemic Chemotherapy, and High-Dose Chemotherapy Followed By Stem Cell Rescue in Treating Patients With Poor-Risk Ewing Sarcoma
 

Status: Recruiting

Condition Summary: Adult Supratentorial Primitive Neuroectodermal Tumor (PNET); Ewing Sarcoma of Bone; Extraosseous Ewing Sarcoma; Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor; Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor; Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor; Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor

 

Last Updated: 14 Aug 2014

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Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma
 

Status: Recruiting

Condition Summary: Adult Supratentorial Primitive Neuroectodermal Tumor (PNET); Childhood Supratentorial Primitive Neuroectodermal Tumor; Ewing Sarcoma of Bone; Extraosseous Ewing Sarcoma; Extraosseous Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor; Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor; Peripheral Primitive Neuroectodermal Tumor of the Kidney; Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor

 

Last Updated: 6 Aug 2014

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Collecting and Storing Biological Samples From Patients With Ewing Sarcoma
 

Status: Recruiting

Condition Summary: Askin Tumor; Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor; Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor; Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor

 

Last Updated: 26 Aug 2014

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