Ehlers-Danlos syndrome hypermobility type

Common Name(s)

Ehlers-Danlos syndrome hypermobility type, Ehlers-Danlos syndrome, type 3

Ehlers-Danlos syndrome (EDS) is a rare tissue disorder that has six specific types. EDS affects a person’s connective tissue, which separates, connects and supports different organs in the body. People with EDS usually cannot make enough normal collagen, a connective tissue protein.

Ehlers-Danlos syndrome hypermobility type (EDS III, EDS type 3) is considered the most common, but least serious type of EDS; however, complications may occur.

The most common sign of EDS III is an unusually large range of joint movement (hypermobility). Symptoms include loose joints, chronic joint pain, and unstable joints (hyperlaxity). The bones in the affected joints tend to fully or partially dislocate, or “pop out of place”. This may occur after minor injuries or on its own. Certain joints (shoulder, knee, jaw) are more likely to dislocate/subluxate, but all joints can be affected. Other symptoms include soft velvety skin, abnormally stretchy skin (hyperextensible), degenerative joint disease, easy bruising, and blood disorders. EDS III commonly affects the stomach and intestines, which may lead to stomach or bowel issues. Heart and blood vessel complications may also occur.

There is no cure for EDS III; it is a lifelong condition that requires close monitoring. Treatments include physical therapy and the use of orthopedic instruments such as braces. Onset can be at any age but it is hard to diagnose in children.

EDS III is usually passed through families in an autosomal dominant manner, meaning that a person only needs to inherit one copy of the defective gene in order to develop the disorder. In most cases, the genetic cause is unknown. If you or your child has been diagnosed with EDS III, talk to your doctor about the most current treatment options. A genetic counselor can be helpful to discuss inheritance and risks to other family members. Support groups are also available for more resources and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ehlers-Danlos syndrome hypermobility type" for support, advocacy or research.

Ehlers-Danlos National Foundation

Ehlers-Danlos National Foundation creates resources for those affected by the connective tissue disorder Ehlers-Danlos Syndrome.

Last Updated: 2 Jul 2015

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Ehlers-Danlos Support UK

EDS UK was set up in 1987 to support, advise and inform those living with Ehlers-Danlos Syndrome. We aim to help them live a full, active and positive life. Over 25 years later, we remain the only UK based charity that exclusively represents and supports people with all types of EDS. We run regular events and conferences to bring our community together, and produce literature and merchandise to increase understanding and improve management of the condition. We have over 30 support groups around the country to provide our members with a local peer support network and we hope to expand this

Last Updated: 17 Aug 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ehlers-Danlos syndrome hypermobility type" for support, advocacy or research.

Ehlers-Danlos National Foundation

Ehlers-Danlos National Foundation creates resources for those affected by the connective tissue disorder Ehlers-Danlos Syndrome.

http://www.ednf.org

Last Updated: 2 Jul 2015

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Ehlers-Danlos Support UK

EDS UK was set up in 1987 to support, advise and inform those living with Ehlers-Danlos Syndrome. We aim to help them live a full, active and positive life. Over 25 years later, we remain the only UK based charity that exclusively represents and supports people with all types of EDS. We run regular events and conferences to bring our community together, and produce literature and merchandise to increase understanding and improve management of the condition. We have over 30 support groups around the country to provide our members with a local peer support network and we hope to expand this

http://www.ehlers-danlos.org

Last Updated: 17 Aug 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ehlers-Danlos syndrome hypermobility type" returned 7 free, full-text research articles on human participants. First 3 results:

Evaluation of kinesiophobia and its correlations with pain and fatigue in joint hypermobility syndrome/Ehlers-Danlos syndrome hypermobility type.
 

Author(s): Claudia Celletti, Marco Castori, Giuseppe La Torre, Filippo Camerota

Journal: Biomed Res Int. 2013 ;2013():580460.

 

Ehlers-Danlos syndrome hypermobility type a. k. a. joint hypermobility syndrome (JHS/EDS-HT) is a hereditary musculoskeletal disorder associating generalized joint hypermobility with chronic pain. Anecdotal reports suggest a prominent role for kinesiophobia in disease manifestations, ...

Last Updated: 12 Aug 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ehlers-Danlos syndrome hypermobility type" returned 1 free, full-text review articles on human participants. First 3 results:

Visceroptosis of the bowel in the hypermobility type of Ehlers-Danlos syndrome: presentation of a rare manifestation and review of the literature.
 

Author(s): Eyal Reinstein, Mark Pimentel, Mitchel Pariani, Stephen Nemec, Thomas Sokol, David L Rimoin

Journal: Eur J Med Genet. 2012 Oct;55(10):548-51.

 

Gastrointestinal complications are common in patients with Ehlers-Danlos syndrome, affecting up to 50% of individuals depending on the subtype. The spectrum of gastrointestinal manifestations is broad and ranges from life threatening spontaneous perforation of the visceral organs ...

Last Updated: 21 Sep 2012

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Wearing a Compression Garment for Patients With Hypermobility Type of Ehlers-Danlos Syndrome
 

Status: Recruiting

Condition Summary: Ehlers-Danlos Syndrome Hypermobility Type

 

Last Updated: 8 Jul 2014

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