Dyserythropoietic Anemia, Congenital Type 1

Common Name(s)

Dyserythropoietic Anemia, Congenital Type 1

Congenital dyserythropoietic anemia (CDA) type 1 is an inherited blood disorder characterized by moderate to severe anemia. It is usually diagnosed in childhood or adolescence, although in some cases, the condition can be detected before birth. Many affected individuals have yellowing of the skin and eyes (jaundice) and an enlarged liver and spleen (hepatosplenomegaly). This condition also causes the body to absorb too much iron, which builds up and can damage tissues and organs. In particular, iron overload can lead to an abnormal heart rhythm (arrhythmia), congestive heart failure, diabetes, and chronic liver disease (cirrhosis). Rarely, people with CDA type I are born with skeletal abnormalities, most often involving the fingers and/or toes. CDA type I usually results from mutations in the CDAN1 gene. It is inherited in an autosomal recessive pattern.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dyserythropoietic Anemia, Congenital Type 1" for support, advocacy or research.

Rare Anemias Foundation

The Rare Anemias Foundation was established to provide support and information to patients with rare anemias that do not fall into other anemia categories. The mission of the foundation is also to encourage research clinical trials on these rare types of anemias for curative purposes.

Last Updated: 10 Jun 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dyserythropoietic Anemia, Congenital Type 1" for support, advocacy or research.

Rare Anemias Foundation

The Rare Anemias Foundation was established to provide support and information to patients with rare anemias that do not fall into other anemia categories. The mission of the foundation is also to encourage research clinical trials on these rare types of anemias for curative purposes.

http://www.rareanemias.org

Last Updated: 10 Jun 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Dyserythropoietic Anemia, Congenital Type 1" returned 0 free, full-text research articles on human participants.

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Dyserythropoietic Anemia, Congenital Type 1" returned 0 free, full-text review articles on human participants.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

GDF 15 in Sickle Cell Disease and Hereditary Spherocytosis
 

Status: Not yet recruiting

Condition Summary: Patients With Thalassemia Intermedia,; Congenital Dyserythropoietic Anemia Type I

 

Last Updated: 12 Sep 2010

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