Dubin-Johnson Syndrome

Common Name(s)

Dubin-Johnson Syndrome, Hyperbilirubinemia type 2

Dubin-Johnson syndrome is a type of hereditary hyperbilirubinemia with a relatively benign course.  Symptoms may include a yellowish color to the skin (jaundice), and a liver that is sometimes enlarged and tender.   The symptoms often do not present until puberty or adulthood. The syndrome interferes with the body's ability to move bilirubin from the liver. In most cases, treatment is not required.  
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dubin-Johnson Syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dubin-Johnson Syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Dubin-Johnson Syndrome" returned 21 free, full-text research articles on human participants. First 3 results:

Dubin-Johnson syndrome coinciding with colon cancer and atherosclerosis.
 

Author(s): Eva Sticova, Milan Elleder, Helena Hulkova, Ondrej Luksan, Martin Sauer, Irena Wunschova-Moudra, Jan Novotny, Milan Jirsa

Journal: World J. Gastroenterol.. 2013 Feb;19(6):946-50.

 

Hyperbilirubinemia has been presumed to prevent the process of atherogenesis and cancerogenesis mainly by decreasing oxidative stress. Dubin-Johnson syndrome is a rare, autosomal recessive, inherited disorder characterized by biphasic, predominantly conjugated hyperbilirubinemia with ...

Last Updated: 22 Feb 2013

Go To URL
[A case of sustained cholestasis caused by acute A viral hepatitis in Dubin-Johnson syndrome].
 

Author(s): Sang Ho Ra, Se Yong Sung, Ho Yeon Jung, Jae Hwang Cha, Soon Koo Baik, Mee Yon Cho, Moon Young Kim

Journal: Korean J Gastroenterol. 2012 Apr;59(4):313-6.

 

Dubin-Johnson syndrome is a rare clinical entity. It shows intermittent symptoms such as chronic or intermittent jaundice, abdominal pain, weakness, nausea, vomiting, anorexia and diarrhea. Symptoms are precipitated or aggravated by pregnancy, alcoholism, surgical procedures and intercurrent ...

Last Updated: 30 Apr 2012

Go To URL
Severe jaundice due to coexistence of Dubin-Johnson syndrome and hereditary spherocytosis: a case report.
 

Author(s): Uğur Korkmaz, Ali Erkan Duman, Deniz Oğütmen Koç, Yeşim Gürbüz, Gökhan Dındar, Fatih Ensaroğlu, Selçuk Yusuf Sener, Omer Sentürk, Sadettin Hülagü

Journal: Turk J Gastroenterol. 2011 Aug;22(4):422-5.

 

Dubin-Johnson syndrome is a chronic, benign, intermittent jaundice, mostly of conjugated hyperbilirubinemia. The level of bilirubin is not expected to be more than 20 mg/dl in this syndrome. In this article, we report a patient who was evaluated for hyperbilirubinemia and liver function ...

Last Updated: 28 Sep 2011

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Dubin-Johnson Syndrome" returned 0 free, full-text review articles on human participants.

 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.