Dermatofibrosarcoma protuberans

Common Name(s)

Dermatofibrosarcoma protuberans

Dermatofibrosarcoma protuberans is an uncommon tumor that arises in the skin. The tumor is firm and often flesh-colored although it can be reddish, bluish, or purplish. The tumor is often found on the chest or shoulders, but it can be found on other parts of the body. Dermatofibrosarcoma protuberans may cause no symptoms, and the initial size of the tumor tends to be around 1 to 5 centimeters. This tumor has a low potential to spread to other tissues. Treatment often involves surgery to remove the tumor, such as by Mohs’ micrographic surgery. If you or a family member has been diagnosed with dermatofibrosarcoma protuberans, talk with your doctor about the most current treatment options.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dermatofibrosarcoma protuberans" for support, advocacy or research.

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Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

Last Updated: 20 Feb 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dermatofibrosarcoma protuberans" for support, advocacy or research.

Logo
Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

http://sarcomaalliance.org

Last Updated: 20 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Dermatofibrosarcoma protuberans" returned 89 free, full-text research articles on human participants. First 3 results:

Effectiveness of Imatinib Mesylate Treatment in a Patient with Dermatofibrosarcoma Protuberans with Pulmonary and Pancreatic Metastases.
 

Author(s): Toshiharu Tatai, Daisuke Gomi, Toshirou Fukushima, Takashi Kobayashi, Nodoka Sekiguchi, Akiyuki Sakamoto, Shigeru Sasaki, Tomonobu Koizumi, Kenji Sano

Journal: Intern. Med.. 2016 ;55(17):2507-11.

 

We herein encountered a case of abdominal wall dermatofibrosarcoma protuberans (DFSP) that developed pulmonary and pancreatic metastases 5 years after complete resection. Because specific rearrangements of the platelet-derived growth factor beta (PDGFB) locus by a novel fluorescence ...

Last Updated: 1 Sep 2016

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Risk factors for distant metastasis of dermatofibrosarcoma protuberans.
 

Author(s): Keiko Hayakawa, Seiichi Matsumoto, Keisuke Ae, Taisuke Tanizawa, Tabu Gokita, Yuki Funauchi, Noriko Motoi

Journal: J Orthop Traumatol. 2016 Sep;17(3):261-6.

 

Dermatofibrosarcoma protuberans (DFSP) may recur locally but rarely metastasizes. Fibrosarcomatous transformation in dermatofibrosarcoma protuberans (FS-DFSP) is said to have worse prognosis compared with ordinary DFSP (O-DFSP). Since DFSP rarely metastasizes, there have been few ...

Last Updated: 26 Aug 2016

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Congenital atrophic dermatofibrosarcoma protuberans detected by COL1A1-PDGFB rearrangement.
 

Author(s): Maki Makino, Shunsuke Sasaoka, Gen Nakanishi, Eiichi Makino, Wataru Fujimoto

Journal:

 

Atrophic variant of dermatofibrosarcoma protuberans (DFSP) is a distinct form of DFSP.

Last Updated: 2 Mar 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Dermatofibrosarcoma protuberans" returned 9 free, full-text review articles on human participants. First 3 results:

Unusual presentation of dermatofibrosarcoma protuberans in a male patient's breast: a case report and review of the literature.
 

Author(s): Mohannad Al Tarakji, Adriana Toro, Isidoro Di Carlo, Kulsoon Junejo

Journal:

 

We herein present a case report and literature review of dermatofibrosarcoma protuberans in the breast of a male patient. A 27-year-old man presented with a painless lump in his right breast with areas of bluish skin discoloration. The diagnostic work-up comprised clinical examination, ...

Last Updated: 3 Aug 2015

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[Dermatofibrosarcoma protuberans : report of 27 cases and review of the literature].
 

Author(s): Nawal Hammas, Ikram Badioui, Kaoutar Znati, Amal Benlemlih, Laila Chbani, Hind El Fatemi, Taoufiq Harmouch, Youssef Bouyahyaoui, Faouzi Boutayeb, Abdelmajid Mrini, Omar Mesbahi, Fatima Zahra Mernissi, Afaf Amarti

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Last Updated: 9 Dec 2014

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[Dermatofibrosarcoma protuberans, particular skin tumor: report of 32 cases and review of the literature].
 

Author(s): Driss Elamrani, Hatim Droussi, Samira Boukind, Keltoum Elatiqi, Meriem Dlimi, Yassine Benchamkha, Saloua Ettalbi

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Last Updated: 30 Mar 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Spanish Registry of Mohs Surgery
 

Status: Recruiting

Condition Summary: Skin Neoplasms; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Dermatofibrosarcoma; Melanoma; Histiocytoma, Malignant Fibrous; Neoplasms, Adnexal and Skin Appendage

 

Last Updated: 11 Sep 2016

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To Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid Tumors
 

Status: Recruiting

Condition Summary: Neuroblastoma; Rhabdomyosarcoma; Ewing's Sarcoma; Ewing's Tumor; Sarcoma, Ewing's; Sarcomas, Epitheliod; Sarcoma, Soft Tissue; Sarcoma, Spindle Cell; Melanoma; Malignant Melanoma; Clinical Oncology; Oncology, Medical; Pediatrics, Osteosarcoma; Osteogenic Sarcoma; Osteosarcoma Tumor; Sarcoma, Osteogenic; Tumors; Cancer; Neoplasia; Neoplasm; Histiocytoma; Fibrosarcoma; Dermatofibrosarcoma

 

Last Updated: 2 Mar 2017

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