Dementia Familial British

Common Name(s)

Dementia Familial British

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dementia Familial British" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dementia Familial British" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Dementia Familial British" returned 7 free, full-text research articles on human participants. First 3 results:

Memory deficits due to familial British dementia BRI2 mutation are caused by loss of BRI2 function rather than amyloidosis.
 

Author(s): Robert Tamayev, Luca Giliberto, Wei Li, Cristina d'Abramo, Ottavio Arancio, Ruben Vidal, Luciano D'Adamio

Journal: J. Neurosci.. 2010 Nov;30(44):14915-24.

 

Familial dementias, which include Alzheimer disease (AD), familial British dementia (FBD), and familial Danish dementia (FDD), are caused by dominantly inherited autosomal mutations and are characterized by the production of amyloidogenic peptides, neurofibrillary tangles (NFTs) and ...

Last Updated: 4 Nov 2010

Go To URL
Expression of BRI2 mRNA and protein in normal human brain and familial British dementia: its relevance to the pathogenesis of disease.
 

Author(s): T Lashley, T Revesz, G Plant, R Bandopadhyay, A J Lees, B Frangione, N W Wood, R de Silva, J Ghiso, A Rostagno, J L Holton

Journal: Neuropathol. Appl. Neurobiol.. 2008 Oct;34(5):492-505.

 

Two different disease-specific mutations in the BRI2 gene, situated on chromosome 13, have been identified as giving rise to familial British dementia (FBD) and familial Danish dementia (FDD). Each mutation results in extension of the open reading frame generating the disease-specific ...

Last Updated: 10 Oct 2008

Go To URL
Hydrogen peroxide is generated during the very early stages of aggregation of the amyloid peptides implicated in Alzheimer disease and familial British dementia.
 

Author(s): Brian J Tabner, Omar M A El-Agnaf, Stuart Turnbull, Matthew J German, Katerina E Paleologou, Yoshihito Hayashi, Leanne J Cooper, Nigel J Fullwood, David Allsop

Journal: J. Biol. Chem.. 2005 Oct;280(43):35789-92.

 

Alzheimer disease and familial British dementia are neurodegenerative diseases that are characterized by the presence of numerous amyloid plaques in the brain. These lesions contain fibrillar deposits of the beta-amyloid peptide (Abeta) and the British dementia peptide (ABri), respectively. ...

Last Updated: 24 Oct 2005

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Dementia Familial British" returned 0 free, full-text review articles on human participants.

 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.