Celiac Disease

Common Name(s)

Celiac Disease

Celiac disease, also known as celiac sprue and gluten-sensitive enteropathy, is a multifactorial disorder of the small intestine that is influenced by both environmental and genetic factors. It is characterized by malabsorption resulting from inflammatory injury to the mucosa of the small intestine after the ingestion of wheat gluten or related rye and barley proteins (summary by {19:Farrell and Kelly, 2002}). Long regarded as gastrointestinal disorder of childhood, the disease is now considered to be a chronic systemic autoimmune disease and is more often diagnosed in adults than in children ({55:Monsuur et al., 2005}). For a discussion of genetic heterogeneity of celiac disease, see MAPPING.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Celiac Disease" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

http://www.agmd-gimotility.org

Last Updated: 28 Feb 2013

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Coeliac Society of Ireland

The mission of the Coeliac Society of Ireland is to improve the quality of life for Coeliacs and those who benefit from a gluten free diet.

http://www.coeliac.ie

Last Updated: 15 Oct 2013

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Gluten Intolerance Group

The mission of the Gluten Intolerance Group of North America® is to support persons with gluten intolerances, celiac disease, dermatitis herpetiformis, and other gluten sensitivities, through consumer and industry services and programs that positively promote healthy lives.

http://www.gluten.net

Last Updated: 24 Oct 2012

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Celiac Disease" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

http://www.agmd-gimotility.org

Last Updated: 28 Feb 2013

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Coeliac Society of Ireland

The mission of the Coeliac Society of Ireland is to improve the quality of life for Coeliacs and those who benefit from a gluten free diet.

http://www.coeliac.ie

Last Updated: 15 Oct 2013

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Gluten Intolerance Group

The mission of the Gluten Intolerance Group of North America® is to support persons with gluten intolerances, celiac disease, dermatitis herpetiformis, and other gluten sensitivities, through consumer and industry services and programs that positively promote healthy lives.

http://www.gluten.net

Last Updated: 24 Oct 2012

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Celiac Disease" returned 701 free, full-text research articles on human participants. First 3 results:

Quantitative and qualitative differences in celiac disease epitopes among durum wheat varieties identified through deep RNA-amplicon sequencing.
 

Author(s): Elma Mj Salentijn, Danny G Esselink, Svetlana V Goryunova, Ingrid M van der Meer, Luud J W J Gilissen, Marinus J M Smulders

Journal:

 

Wheat gluten is important for the industrial quality of bread wheat (Triticum aestivum L.) and durum wheat (T. turgidum L.). Gluten proteins are also the source of immunogenic peptides that can trigger a T cell reaction in celiac disease (CD) patients, leading to inflammatory responses ...

Last Updated: 13 Jan 2014

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Clinical picture of classical, atypical and silent celiac disease in children and adolescents.
 

Author(s): Barbara Iwańczak, Krzysztof Matusiewicz, Franciszek Iwańczak

Journal: Adv Clin Exp Med. ;22(5):667-73.

 

Celiac disease is a frequent disease of the alimentary tract in children. Clinical presentation of the disease is variable and depends on type of the disease.

Last Updated: 28 Nov 2013

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Pyoderma gangrenosum in refractory celiac disease: a case report.
 

Author(s): Silvia Sedda, Roberta Caruso, Irene Marafini, Elena Campione, Augusto Orlandi, Francesco Pallone, Giovanni Monteleone

Journal:

 

Pyoderma gangrenosum is an inflammatory neutrophilic dermatosis characterized by painful cutaneous ulcerations and often associated with systemic inflammatory and neoplastic diseases. Here we report the first case of pyoderma gangrenosum in a patient with refractory celiac disease.

Last Updated: 2 Dec 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Celiac Disease" returned 100 free, full-text review articles on human participants. First 3 results:

Dermatitis herpetiformis, the celiac disease of the skin!
 

Author(s): Lorete Maria da Silva Kotze

Journal: Arq Gastroenterol. ;50(3):231-5.

 

Last Updated: 10 Dec 2013

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Celiac disease and autoimmune-associated conditions.
 

Author(s): Eugenia Lauret, Luis Rodrigo

Journal: Biomed Res Int. 2013 ;2013():127589.

 

Celiac disease (CD) is frequently accompanied by a variety of extradigestive manifestations, thus making it a systemic disease rather than a disease limited to the gastrointestinal tract. This is primarily explained by the fact that CD belongs to the group of autoimmune diseases. ...

Last Updated: 28 Aug 2013

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2013 update on celiac disease and eosinophilic esophagitis.
 

Author(s): Rinaldo Pellicano, Claudio De Angelis, Davide Giuseppe Ribaldone, Sharmila Fagoonee, Marco Astegiano

Journal:

 

Celiac disease is a chronic, immune-mediated disorder, characterized by small intestinal inflammation and villous atrophy after the ingestion of gluten by genetically susceptible individuals. Several extraintestinal manifestations have been associated to celiac disease. Eosinophilic ...

Last Updated: 26 Aug 2013

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Detection of Celiac Disease in Patients With Hypothyroidism
 

Status: Recruiting

Condition Summary: Celiac Disease; Hypothyroidism; Celiac Sprue; Malabsorption

 

Last Updated: 21 May 2013

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Celiac Disease and Diabetes- Dietary Intervention and Evaluation Trial
 

Status: Recruiting

Condition Summary: Celiac Disease; Diabetes Mellitus, Type 1

 

Last Updated: 6 Aug 2013

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Oral AGY for Celiac Disease
 

Status: Not yet recruiting

Condition Summary: Celiac Disease

 

Last Updated: 11 Mar 2014

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