Celiac Disease

Common Name(s)

Celiac Disease

Celiac disease is an autoimmune disorder that damages the small intestine and inhibits absorption of nutrients. People with celiac disease cannot tolerate gluten, a protein in wheat, rye, barley, and in some products such as medicines, vitamins, and lip balms. When affected people eat food with gluten, or use a product with gluten, the immune system reacts by damaging tiny parts of the lining of the small intestine called villi. Because villi normally allow the blood to absorb nutrients from food, affected individuals become malnourished. Classic signs and symptoms are caused by inflammation of the gastrointestinal tract and may include diarrhea, weight loss, abdominal pain, swelling, and food intolerance. However, many people have other symptoms involving many body systems, and some people have no symptoms. While celiac disease tends to run in families, it does not follow a specific inheritance pattern. The risk to develop celiac disease is raised by having certain forms of the HLA-DQA1 and HLA-DQB1 genes. Treatment is a lifelong, gluten-free diet.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Celiac Disease" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

Last Updated: 28 Feb 2013

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Coeliac Society of Ireland

The mission of the Coeliac Society of Ireland is to improve the quality of life for Coeliacs and those who benefit from a gluten free diet.

Last Updated: 15 Oct 2013

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Gluten Intolerance Group

The mission of the Gluten Intolerance Group of North America® is to support persons with gluten intolerances, celiac disease, dermatitis herpetiformis, and other gluten sensitivities, through consumer and industry services and programs that positively promote healthy lives.

Last Updated: 24 Oct 2012

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Celiac Disease" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

http://www.agmd-gimotility.org

Last Updated: 28 Feb 2013

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Coeliac Society of Ireland

The mission of the Coeliac Society of Ireland is to improve the quality of life for Coeliacs and those who benefit from a gluten free diet.

http://www.coeliac.ie

Last Updated: 15 Oct 2013

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Gluten Intolerance Group

The mission of the Gluten Intolerance Group of North America® is to support persons with gluten intolerances, celiac disease, dermatitis herpetiformis, and other gluten sensitivities, through consumer and industry services and programs that positively promote healthy lives.

http://www.gluten.net

Last Updated: 24 Oct 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Celiac Disease" returned 749 free, full-text research articles on human participants. First 3 results:

Risk of celiac disease according to HLA haplotype and country.
 

Author(s): Edwin Liu, Hye-Seung Lee, Daniel Agardh

Journal: N. Engl. J. Med.. 2014 Sep;371(11):1074.

 

Last Updated: 11 Sep 2014

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Celiac disease in an Ethiopian Jew.
 

Author(s): Z Ackerman, J Livovsky, D M Livovsky

Journal: Isr. Med. Assoc. J.. 2014 Jun;16(6):395-6.

 

Last Updated: 25 Jul 2014

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Celiac disease a rare cause of nephrogenic ascites.
 

Author(s): Mahmood Dhahir Al-Mendalawi

Journal: Saudi J Kidney Dis Transpl. 2014 Jul;25(4):893-4.

 

Last Updated: 27 Jun 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Celiac Disease" returned 116 free, full-text review articles on human participants. First 3 results:

Cereal-based gluten-free food: how to reconcile nutritional and technological properties of wheat proteins with safety for celiac disease patients.
 

Author(s): Carmela Lamacchia, Alessandra Camarca, Stefania Picascia, Aldo Di Luccia, Carmen Gianfrani

Journal:

 

The gluten-free diet is, to date, the only efficacious treatment for patients with Celiac Disease. In recent years, the impressive rise of Celiac Disease incidence, dramatically prompted changes in the dietary habit of an increasingly large population, with a rise in demand of gluten-free ...

Last Updated: 31 Jan 2014

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Celiac disease and overweight in children: an update.
 

Author(s): Antonella Diamanti, Teresa Capriati, Maria Sole Basso, Fabio Panetta, Vincenzo Maria Di Ciommo Laurora, Francesca Bellucci, Fernanda Cristofori, Ruggiero Francavilla

Journal:

 

The clinical presentation of celiac disease in children is very variable and differs with age. The prevalence of atypical presentations of celiac disease has increased over the past 2 decades. Several studies in adults and children with celiac disease indicate that obesity/overweight ...

Last Updated: 23 Jan 2014

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[Genetic and epigenetic aspects of celiac disease].
 

Author(s): Dorottya Kocsis, Nóra Béres, Gábor Veres, Dolóresz Szabó, Katalin Eszter Müller, András Arató, Márk Juhász

Journal: Orv Hetil. 2014 Jan;155(3):83-8.

 

Genetic background of coeliac disease has been subjects to intensive research since decades. However, only results of HLA phenotyping have been taken over to routine clinical practice. Meanwhile, data on the role of epigenetical factors in the manifestation of diseases have been emerging. ...

Last Updated: 13 Jan 2014

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Detection of Celiac Disease in Patients With Hypothyroidism
 

Status: Recruiting

Condition Summary: Celiac Disease; Hypothyroidism; Celiac Sprue; Malabsorption

 

Last Updated: 21 May 2013

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Antibody Treatment for Advanced Celiac Disease
 

Status: Recruiting

Condition Summary: Celiac Disease; Celiac Sprue; Gluten Enteropathy; Gluten-Sensitive Enteropathy

 

Last Updated: 13 May 2014

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Celiac Disease and Unexplained Iron Deficiency in a Primary Care Setting
 

Status: Not yet recruiting

Condition Summary: Celiac Disease; Iron Deficiency; Iron Malabsorption

 

Last Updated: 13 Oct 2014

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