Burkitt's Lymphoma

Common Name(s)

Burkitt's Lymphoma

Burkitt lymphoma is a rare, aggressive B-cell lymphoma that accounts for 30 to 50% of lymphomas in children but only 1 to 2% of lymphomas in adults ({10:Harris and Horning, 2006}). It results from chromosomal translocations that involve the MYC gene ({190080}) and either the lambda or the kappa light chain immunoglobulin genes ({147220}, {147200}). Burkitt lymphoma is causally related to the Epstein-Barr virus (EBV), although the pathogenetic mechanisms are not clear.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Burkitt's Lymphoma" for support, advocacy or research.

National Bone Marrow Transplant Link

The mission of the National Bone Marrow Transplant Link is to help patients, caregivers, and families cope with the social and emotional challenges of bone marrow/stem cell transplant from diagnosis through survivorship by providing vital information and personalized support services.

Last Updated: 20 Feb 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Burkitt's Lymphoma" for support, advocacy or research.

National Bone Marrow Transplant Link

The mission of the National Bone Marrow Transplant Link is to help patients, caregivers, and families cope with the social and emotional challenges of bone marrow/stem cell transplant from diagnosis through survivorship by providing vital information and personalized support services.

http://www.nbmtlink.org

Last Updated: 20 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Burkitt's Lymphoma" returned 451 free, full-text research articles on human participants. First 3 results:

[Burkitt's lymphoma of the oral cavity: about a case].
 

Author(s): Lamia Kissi, Rajaa El Bouihi, Mouna Lamchahab, Ahmed Alaoui, Ihsane Benyahya

Journal:

 

Burkitt's lymphoma (LB) is a type of malignant non-Hodgkin's lymphoma originating from malignant B-cell transformation and proliferation. Positive confirmation is based on biopsy of the tumor mass or bone marrow aspiration revealing the presence of tumor cells. We here report the ...

Last Updated: 28 Apr 2017

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Unusual multiple metastatic localisations in adult Burkitt's lymphoma. A case report.
 

Author(s): Georgiana Nagy, Romeo Chira, Doinita Crisan, Mihai Munteanu, Petru Adrian Mircea

Journal: Med Ultrason. 2016 Dec;18(4):518-520.

 

Burkitt's lymphoma is an aggressive B-cell non-Hodgkin lymphoma. It is less common in adults accounting for less thanĀ 5% of non-Hodgkin lymphoma cases. Radiological methods (ultrasonography, computed tomography) are indispensable forĀ the initial evaluation and appreciation of organ ...

Last Updated: 16 Dec 2016

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Different N-terminal isoforms of Oct-1 control expression of distinct sets of genes and their high levels in Namalwa Burkitt's lymphoma cells affect a wide range of cellular processes.
 

Author(s): Elizaveta V Pankratova, Alexander G Stepchenko, Tatiana Portseva, Vladic A Mogila, Sofia G Georgieva

Journal: Nucleic Acids Res.. 2016 Nov;44(19):9218-9230.

 

Oct-1 transcription factor has various functions in gene regulation. Its expression level is increased in several types of cancer and is associated with poor survival prognosis. Here we identified distinct Oct-1 protein isoforms in human cells and compared gene expression patterns ...

Last Updated: 13 Jul 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Burkitt's Lymphoma" returned 19 free, full-text review articles on human participants. First 3 results:

The Link between Plasmodium falciparum Malaria and Endemic Burkitt's Lymphoma-New Insight into a 50-Year-Old Enigma.
 

Author(s): David Thorley-Lawson, Kirk W Deitsch, Karen A Duca, Charles Torgbor

Journal:

 

Last Updated: 22 Jan 2016

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Primary Burkitt's lymphoma of the breast without Epstein-Barr virus infection: A case report and literature review.
 

Author(s): Jianguo Wei, Caixia Lin, Chunwei Xu, Qun Xi, Cheng Wang

Journal: Indian J Pathol Microbiol. ;58(4):546-9.

 

Burkitt lymphoma (BL) is a highly aggressive neoplasm, which arising from the germinal center or post germinal center B-cell. Primary breast lymphomas are extremely rare, and the most common histologic type is diffuse large B-cell lymphoma. Primary BL of the breast is much less common ...

Last Updated: 9 Nov 2015

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Burkitt's lymphoma developing post liver transplantation: posttransplant lymphoproliferative disorders international survey.
 

Author(s): Hossein Khedmat, Mohammad Ebrahim Ghamar-Chehreh, Mohsen Amini, Saeed Taheri

Journal: Saudi J Kidney Dis Transpl. 2014 Nov;25(6):1290-2.

 

Last Updated: 14 Nov 2014

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Safety and Efficacy of CART-19 Cells in B-cell Acute Lymphoblastic Leukemia (B-ALL).
 

Status: Recruiting

Condition Summary: B-cell Acute Lymphoblastic Leukemia

 

Last Updated: 4 Oct 2016

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Dose Escalation Study of UCART19 in Adult Patients With Relapsed / Refractory B-cell Acute Lymphoblastic Leukaemia
 

Status: Recruiting

Condition Summary: B-cell Acute Lymphoblastic Leukemia

 

Last Updated: 19 May 2017

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Epidemiology of Burkitt Lymphoma in East Africa Children or Minors (EMBLEM)
 

Status: Recruiting

Condition Summary: Lymphoma, Non-Hodgkin; Malaria; Herpesvirus 4, Human

 

Last Updated: 4 Aug 2017

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