Burkitt's Lymphoma

Common Name(s)

Burkitt's Lymphoma

Burkitt lymphoma is a rare, aggressive B-cell lymphoma that accounts for 30 to 50% of lymphomas in children but only 1 to 2% of lymphomas in adults ({10:Harris and Horning, 2006}). It results from chromosomal translocations that involve the MYC gene ({190080}) and either the lambda or the kappa light chain immunoglobulin genes ({147220}, {147200}). Burkitt lymphoma is causally related to the Epstein-Barr virus (EBV), although the pathogenetic mechanisms are not clear.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Burkitt's Lymphoma" for support, advocacy or research.

National Bone Marrow Transplant Link

The mission of the National Bone Marrow Transplant Link is to help patients, caregivers, and families cope with the social and emotional challenges of bone marrow/stem cell transplant from diagnosis through survivorship by providing vital information and personalized support services.

Last Updated: 20 Feb 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Burkitt's Lymphoma" for support, advocacy or research.

National Bone Marrow Transplant Link

The mission of the National Bone Marrow Transplant Link is to help patients, caregivers, and families cope with the social and emotional challenges of bone marrow/stem cell transplant from diagnosis through survivorship by providing vital information and personalized support services.

http://www.nbmtlink.org

Last Updated: 20 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Burkitt's Lymphoma" returned 403 free, full-text research articles on human participants. First 3 results:

IRAK4 is essential for TLR9-induced suppression of Epstein-Barr virus BZLF1 transcription in Akata Burkitt's lymphoma cells.
 

Author(s): Marc Jordi, Jeannine Marty, Vanessa Mordasini, Anna L√ľnemann, Scott McComb, Michele Bernasconi, David Nadal

Journal:

 

Burkitt's lymphoma (BL) is the most common childhood cancer in equatorial Africa, and is endemic to areas where people are chronically co-infected with Epstein-Barr virus (EBV) and the malaria pathogen Plasmodium falciparum. The contribution of these pathogens in the oncogenic process ...

Last Updated: 31 Dec 1969

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[Burkitt's lymphoma of the oral cavity: about a case].
 

Author(s): Lamia Kissi, Rajaa El Bouihi, Mouna Lamchahab, Ahmed Alaoui, Ihsane Benyahya

Journal:

 

Burkitt's lymphoma (LB) is a type of malignant non-Hodgkin's lymphoma originating from malignant B-cell transformation and proliferation. Positive confirmation is based on biopsy of the tumor mass or bone marrow aspiration revealing the presence of tumor cells. We here report the ...

Last Updated: 31 Dec 1969

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Survival predictors of Burkitt's lymphoma in children, adults and elderly in the United States during 2000-2013.
 

Author(s): Fahad Mukhtar, Paolo Boffetta, Harvey A Risch, Jong Y Park, Omonigho M Bubu, Lindsay Womack, Thuan V Tran, Janice C Zgibor, Hung N Luu

Journal: Int. J. Cancer. 2017 04;140(7):1494-1502.

 

Burkitt's Lymphoma (BL) has three peaks of occurrence, in children, adults and elderly, at 10, 40 and 70 years respectively. To the best of our knowledge, no study has been conducted to assess predictors of survival in the three age groups. We hypothesized that survival predictors ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Burkitt's Lymphoma" returned 20 free, full-text review articles on human participants. First 3 results:

Primary ovarian Burkitt's lymphoma: a rare oncological problem in gynaecology: a review of literature.
 

Author(s): Anna Stepniak, Piotr Czuczwar, Piotr Szkodziak, Ewa Wozniakowska, Slawomir Wozniak, Tomasz Paszkowski

Journal: Arch. Gynecol. Obstet.. 2017 Oct;296(4):653-660.

 

This review presents the information about epidemiology, clinical manifestation, diagnosis and treatment of primary ovarian Burkitt's lymphoma (BL), including a literature search of available BL cases. The purpose of this review is to draw clinicians' attention to the possibility ...

Last Updated: 31 Dec 1969

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The Link between Plasmodium falciparum Malaria and Endemic Burkitt's Lymphoma-New Insight into a 50-Year-Old Enigma.
 

Author(s): David Thorley-Lawson, Kirk W Deitsch, Karen A Duca, Charles Torgbor

Journal:

 

Last Updated: 31 Dec 1969

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Primary Burkitt's lymphoma of the breast without Epstein-Barr virus infection: A case report and literature review.
 

Author(s): Jianguo Wei, Caixia Lin, Chunwei Xu, Qun Xi, Cheng Wang

Journal: Indian J Pathol Microbiol. ;58(4):546-9.

 

Burkitt lymphoma (BL) is a highly aggressive neoplasm, which arising from the germinal center or post germinal center B-cell. Primary breast lymphomas are extremely rare, and the most common histologic type is diffuse large B-cell lymphoma. Primary BL of the breast is much less common ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Safety and Efficacy of CART-19 Cells in B-cell Acute Lymphoblastic Leukemia (B-ALL).
 

Status: Recruiting

Condition Summary: B-cell Acute Lymphoblastic Leukemia

 

Last Updated: 28 Dec 2017

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Dose Escalation Study of UCART19 in Adult Patients With Relapsed / Refractory B-cell Acute Lymphoblastic Leukaemia
 

Status: Recruiting

Condition Summary: B-cell Acute Lymphoblastic Leukemia

 

Last Updated: 26 Feb 2018

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Epidemiology of Burkitt Lymphoma in East Africa Children or Minors (EMBLEM)
 

Status: Recruiting

Condition Summary: Lymphoma, Non-Hodgkin; Malaria; Herpesvirus 4, Human

 

Last Updated: 5 Oct 2017

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