Essential tremor

Common Name(s)

Essential tremor, Benign Essential Tremor Syndrome

Essential tremor is a disorder of the nervous system that causes involuntary, rhythmic shaking (tremor), especially in the hands. It involves tremor without any other signs or symptoms, and is distinguished from tremor that results from other disorders or known causes, such as tremors seen with Parkinson disease or head trauma.  Essential tremor (sometimes called benign essential tremor) is the most common of the more than 20 types of tremor.  Essential tremor is a complex disorder. Several genes are believed to help determine an individual's risk of developing this condition. Environmental factors may also be involved.  In mild cases, treatment may not be necessary. In cases where symptoms interfere with daily living, medications may help to relieve symptoms.  

 

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Essential tremor" for support, advocacy or research.

International Essential Tremor Foundation

The International Essential Tremor Foundation is a worldwide organization that funds research to find the cause of essential tremor (ET) that will lead to better treatment and a cure, increases public awareness about ET, and provides educational materials, tools, and support for healthcare providers, the public, and those affected by ET.

www.essentialtremor.org

Last Updated: 27 Dec 2012

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Essential tremor" for support, advocacy or research.

International Essential Tremor Foundation

The International Essential Tremor Foundation is a worldwide organization that funds research to find the cause of essential tremor (ET) that will lead to better treatment and a cure, increases public awareness about ET, and provides educational materials, tools, and support for healthcare providers, the public, and those affected by ET.

www.essentialtremor.org

Last Updated: 27 Dec 2012

View Details

 

General Support Organizations

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General Resources

Essential Tremor Website

Online source of free educational materials, that include brochures, flyers, webinars, videos, physician referral and support.

Updated 27 Dec 2012

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Blogs

Tremor Talk Blog

Posting of brief entries, links to news, photos, and other conversation pieces to help keep those affected by ET informed of the latest happenings.

Updated 27 Dec 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Essential tremor" returned 222 free, full-text research articles on human participants. First 3 results:

Phase dependent modulation of tremor amplitude in essential tremor through thalamic stimulation.
 

Author(s): Hayriye Cagnan, John-Stuart Brittain, Simon Little, Thomas Foltynie, Patricia Limousin, Ludvic Zrinzo, Marwan Hariz, Carole Joint, James Fitzgerald, Alexander L Green, Tipu Aziz, Peter Brown

Journal: Brain. 2013 Oct;136(Pt 10):3062-75.

 

High frequency deep brain stimulation of the thalamus can help ameliorate severe essential tremor. Here we explore how the efficacy, efficiency and selectivity of thalamic deep brain stimulation might be improved in this condition. We started from the hypothesis that the effects of ...

Last Updated: 27 Sep 2013

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A pilot study of focused ultrasound thalamotomy for essential tremor.
 

Author(s): W Jeffrey Elias, Diane Huss, Tiffini Voss, Johanna Loomba, Mohamad Khaled, Eyal Zadicario, Robert C Frysinger, Scott A Sperling, Scott Wylie, Stephen J Monteith, Jason Druzgal, Binit B Shah, Madaline Harrison, Max Wintermark

Journal: N. Engl. J. Med.. 2013 Aug;369(7):640-8.

 

Recent advances have enabled delivery of high-intensity focused ultrasound through the intact human cranium with magnetic resonance imaging (MRI) guidance. This preliminary study investigates the use of transcranial MRI-guided focused ultrasound thalamotomy for the treatment of essential tremor.

Last Updated: 15 Aug 2013

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Abnormal regional homogeneity in patients with essential tremor revealed by resting-state functional MRI.
 

Author(s): Weidong Fang, Fajin Lv, Tianyou Luo, Oumei Cheng, Wei Liao, Ke Sheng, Xuefeng Wang, Fei Wu, Yida Hu, Jing Luo, Qing X Yang, Han Zhang

Journal:

 

Essential tremor (ET) is one of the most common movement disorders in human adults. It can be characterized as a progressive neurological disorder of which the most recognizable feature is a tremor of the arms or hands that is apparent during voluntary movements such as eating and ...

Last Updated: 22 Jul 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Essential tremor" returned 21 free, full-text review articles on human participants. First 3 results:

Essential tremor followed by progressive supranuclear palsy: postmortem reports of 11 patients.
 

Author(s): Elan D Louis, Rachel Babij, Karen Ma, Etty Cortés, Jean-Paul G Vonsattel

Journal: J. Neuropathol. Exp. Neurol.. 2013 Jan;72(1):8-17.

 

For many years, clinicians have commented on the development of signs of parkinsonism among their essential tremor (ET) patients, but the links between ET and parkinsonism are not well understood. We report 11 (12.4%) of 89 ET patients who were prospectively collected at the Essential ...

Last Updated: 24 Dec 2012

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[Essential tremor and Parkinson's disease: are they associated?].
 

Author(s): Andrés Labiano-Fontcuberta, Julián Benito-León

Journal: Rev Neurol. 2012 Oct;55(8):479-89.

 

There is now growing evidence that essential tremor and Parkinson's disease are related.

Last Updated: 11 Oct 2012

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Distinguishing essential tremor from Parkinson's disease: bedside tests and laboratory evaluations.
 

Author(s): Mary Ann Thenganatt, Elan D Louis

Journal: Expert Rev Neurother. 2012 Jun;12(6):687-96.

 

Distinguishing essential tremor from Parkinson's disease can be challenging, both in the early stages of these diseases and as these diseases progress. Various tremor types (rest, postural, kinetic and intention) may be seen in both essential tremor and Parkinson's disease. Furthermore, ...

Last Updated: 1 Jun 2012

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Imaging in the Diagnosis of Parkinson's Disease and Essential Tremor
 

Status: Recruiting

Condition Summary: Parkinson's Disease; Essential Tremor

 

Last Updated: 26 Oct 2012

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Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor
 

Status: Recruiting

Condition Summary: Tremor; Essential Tremor; Parkinson Disease; Radiosurgery; Quality of Life

 

Last Updated: 1 Apr 2014

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Efficacy of Pramipexole Extended Release in the Treatment of Essential Tremor
 

Status: Not yet recruiting

Condition Summary: Essential Tremor

 

Last Updated: 15 Dec 2011

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