Essential tremor

Common Name(s)

Essential tremor, Benign Essential Tremor Syndrome

Essential tremor is a disorder of the nervous system that causes involuntary, rhythmic shaking (tremor), especially in the hands. It involves tremor without any other signs or symptoms, and is distinguished from tremor that results from other disorders or known causes, such as tremors seen with Parkinson disease or head trauma.  Essential tremor (sometimes called benign essential tremor) is the most common of the more than 20 types of tremor. The causes of essential tremor are unknown. Several genes as well as environmental factors likely play a role in a person's risk of developing this complex condition.  In mild cases, treatment may not be necessary. In cases where symptoms interfere with daily living, medications may help to relieve symptoms.  

 

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Essential tremor" for support, advocacy or research.

International Essential Tremor Foundation

The International Essential Tremor Foundation is a worldwide organization that funds research to find the cause of essential tremor (ET) that will lead to better treatment and a cure, increases public awareness about ET, and provides educational materials, tools, and support for healthcare providers, the public, and those affected by ET.

Last Updated: 27 Dec 2012

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Essential tremor" for support, advocacy or research.

International Essential Tremor Foundation

The International Essential Tremor Foundation is a worldwide organization that funds research to find the cause of essential tremor (ET) that will lead to better treatment and a cure, increases public awareness about ET, and provides educational materials, tools, and support for healthcare providers, the public, and those affected by ET.

www.essentialtremor.org

Last Updated: 27 Dec 2012

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

General Resources

Essential Tremor Website

Online source of free educational materials, that include brochures, flyers, webinars, videos, physician referral and support.

Updated 27 Dec 2012

Go To URL
 
 
Top

Blogs

Tremor Talk Blog

Posting of brief entries, links to news, photos, and other conversation pieces to help keep those affected by ET informed of the latest happenings.

Updated 27 Dec 2012

Go To URL
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Essential tremor" returned 295 free, full-text research articles on human participants. First 3 results:

Heme Oxygenase 1 and 2 Common Genetic Variants and Risk for Essential Tremor.
 

Author(s): Pedro Ayuso, José A G Agúndez, Hortensia Alonso-Navarro, Carmen Martínez, Julián Benito-León, Sara Ortega-Cubero, Oswaldo Lorenzo-Betancor, Pau Pastor, Tomás López-Alburquerque, Elena García-Martín, Félix J Jiménez-Jiménez

Journal: Medicine (Baltimore). 2015 Jun;94(24):e968.

 

Several reports suggested a role of heme oxygenase genes 1 and 2 (HMOX1 and HMOX2) in modifying the risk to develop Parkinson disease (PD). Because essential tremor (ET) and PD share phenotypical and, probably, etiologic factors of the similarities, we analyzed whether such genes ...

Last Updated: 20 Jun 2015

Go To URL
The phase difference between neural drives to antagonist muscles in essential tremor is associated with the relative strength of supraspinal and afferent input.
 

Author(s): Juan A Gallego, Jakob L Dideriksen, Ales Holobar, Jaime Ibáñez, Vojko Glaser, Juan P Romero, Julián Benito-León, José L Pons, Eduardo Rocon, Dario Farina

Journal: J. Neurosci.. 2015 Jun;35(23):8925-37.

 

The pathophysiology of essential tremor (ET), the most common movement disorder, is not fully understood. We investigated which factors determine the variability in the phase difference between neural drives to antagonist muscles, a long-standing observation yet unexplained. We used ...

Last Updated: 11 Jun 2015

Go To URL
HTRA2 p.G399S in Parkinson disease, essential tremor, and tremulous cervical dystonia.
 

Author(s): Charalampos Tzoulis, Tetyana Zayats, Per Morten Knappskog, Bernd Müller, Jan Petter Larsen, Ole-Bjørn Tysnes, Laurence A Bindoff, Stefan Johansson, Kristoffer Haugarvoll

Journal: Proc. Natl. Acad. Sci. U.S.A.. 2015 May;112(18):E2268.

 

Last Updated: 6 May 2015

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Essential tremor" returned 30 free, full-text review articles on human participants. First 3 results:

Neuroimaging essentials in essential tremor: a systematic review.
 

Author(s): Sarvi Sharifi, Aart J Nederveen, Jan Booij, Anne-Fleur van Rootselaar

Journal:

 

Essential tremor is regarded to be a disease of the central nervous system. Neuroimaging is a rapidly growing field with potential benefits to both diagnostics and research. The exact role of imaging techniques with respect to essential tremor in research and clinical practice is ...

Last Updated: 28 Jul 2014

Go To URL
MR-guided focused ultrasound: a new generation treatment of Parkinson's disease, essential tremor and neuropathic pain.
 

Author(s): Pawel Piotr Dobrakowski, Agnieszka Kamila Machowska-Majchrzak, Beata Labuz-Roszak, Krzysztof Grzegorz Majchrzak, Ewa Kluczewska, Krystyna Barbara Pierzchała

Journal: Interv Neuroradiol. ;20(3):275-82.

 

The application of high intense focused ultrasound (HIFU) is currently the subject of many experimental and clinical trials. The combination of HIFU with MRI guidance known as MR-guided focused ultrasound (MRgFUS) appears to be particularly promising to ablate tissues located deep ...

Last Updated: 30 Jun 2014

Go To URL
Essential tremor: from bedside to bench and back to bedside.
 

Author(s): Elan D Louis

Journal: Curr. Opin. Neurol.. 2014 Aug;27(4):461-7.

 

The last several years have witnessed a remarkable increase in research on essential tremor, with consequent advances in our understanding of this entity. An attempt to both summarize and frame this work has not been undertaken.

Last Updated: 3 Jul 2014

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor
 

Status: Recruiting

Condition Summary: Tremor; Essential Tremor; Parkinson Disease; Radiosurgery; Quality of Life

 

Last Updated: 9 Dec 2015

Go to URL
Demand-driven Management of Essential Tremor
 

Status: Recruiting

Condition Summary: Essential Tremor

 

Last Updated: 30 Nov 2015

Go to URL
Gamma Knife Radiosurgery for Treatment of Essential Tremor
 

Status: Recruiting

Condition Summary: Essential Tremor

 

Last Updated: 4 Jun 2015

Go to URL