Attenuated Familial Adenomatous Polyposis (AFAP)

Common Name(s)

Attenuated Familial Adenomatous Polyposis (AFAP), Attenuated FAP

Attenuated familial adenomatous polyposis (AFAP) is an inherited condition that causes cancer of the large intestine (colon) and rectum. It is a milder form of classic familial adenomatous polyposis that is characterized by fewer colon polyps (an average of 30) and a delay in the development of colon cancer (average age 50 to 55 years). Other signs and symptoms may include dental abnormalities; desmoid tumors; and benign and malignant (cancerous) tumors of the duodenum (a section of the small intestine), stomach, bones, skin, thyroid and other tissues. AFAP is caused by mutations in the APC gene and is inherited in an autosomal dominant manner. AFAP is generally managed with regular screening to detect if and when polyps develop.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Attenuated Familial Adenomatous Polyposis (AFAP)" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

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