Antiphospholipid Syndrome

Common Name(s)

Antiphospholipid Syndrome, Antiphospholipid Antibody Syndrome

Antiphospholipid syndrome is an autoimmune disorder. It is characterized by high levels of multiple different antibodies that are associated with clots in the arteries and veins. Symptoms vary and can include blood clots, miscarriage, rash, chronic headaches, dementia, and seizures. Treatment involves thinning the blood to reduce clotting.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Antiphospholipid Syndrome" for support, advocacy or research.

APS Foundation of America, Inc.

The APS Foundation of America, Inc. is dedicated to fostering and facilitating joint efforts in the areas of education, public awareness, research and patient services in an effective and ethical manner.

Last Updated: 12 Aug 2013

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International Scleroderma Network

Our mission is to provide stellar worldwide research, support, education and awareness for scleroderma and related illnesses.

Last Updated: 18 Apr 2010

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Antiphospholipid Syndrome" for support, advocacy or research.

APS Foundation of America, Inc.

The APS Foundation of America, Inc. is dedicated to fostering and facilitating joint efforts in the areas of education, public awareness, research and patient services in an effective and ethical manner.

http://www.apsfa.org

Last Updated: 12 Aug 2013

View Details
International Scleroderma Network

Our mission is to provide stellar worldwide research, support, education and awareness for scleroderma and related illnesses.

http://www.sclero.org/

Last Updated: 18 Apr 2010

View Details

 

General Support Organizations

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General Resources

Antiphospholipid Antibody Syndrome

This pamphlet is a layman’s terms summary of Antiphospholipid Syndrome (APS). It covers such topics as diagnosis, symptoms, treatment, and coping. It is meant for patients newly diagnosed, however would also be good for informing friends and family

Updated 13 Nov 2012

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Antiphospholipid Antibody Syndrome (APS) & Pregnancy

Antiphospholipid antibody syndrome (APS) is an illness that involve the immune system, and causes increased clotting of the blood. Normally antibodies, chemicals made by the immune system, are helpful in fighting germs or viral infections from outsid

Updated 13 Nov 2012

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APS Foundation of America, Inc Fan Page

The APS Foundation of America, Inc. is the leading United States nonprofit health agency dedicated to bringing national awareness to Antiphospholipid Antibody Syndrome (APS).

Updated 13 Nov 2012

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Blogs

APS Friends & Support Forum

Are you looking for Support for Antiphospholipid Antibody Syndrome, APS, APLS, APLA, Hughes Syndrome, or Sticky Blood? Well you've come to the right place! This is an private forum for people who have Antiphospholipid Antibody Syndrome, friends, fam

Updated 13 Nov 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Antiphospholipid Syndrome" returned 718 free, full-text research articles on human participants. First 3 results:

Evaluation of the Clinical Performance of a Novel Chemiluminescent Immunoassay for Detection of Anticardiolipin and Anti-Beta2-Glycoprotein 1 Antibodies in the Diagnosis of Antiphospholipid Syndrome.
 

Author(s): Shulan Zhang, Ziyan Wu, Ping Li, Yina Bai, Fengchun Zhang, Yongzhe Li

Journal: Medicine (Baltimore). 2015 Nov;94(46):e2059.

 

Detection of antiphospholipid antibodies represents the first-line approach for diagnosis of antiphospholipid syndrome (APS). In this study, we evaluated the clinical performance of a novel chemiluminescence assay (CIA) in detection of IgG/IgM/IgA anti-cardiolipin (aCL) and IgG/IgM/IgA ...

Last Updated: 20 Nov 2015

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[Catastrophic postpartum antiphospholipid syndrome simulating peritonitis; a diagnostic trap].
 

Author(s): Chaouki Mrazguia, Haykel Makni, Marwen Najjar, Amjed Ajili, Hedi Charrada

Journal: Tunis Med. 2015 Mar;93(3):198-9.

 

Last Updated: 15 Sep 2015

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Primary Antiphospholipid Syndrome Associated with Diffuse Alveolar Hemorrhage and Pulmonary Thromboembolism.
 

Author(s): Takuma Isshiki, Keishi Sugino, Kyoko Gocho, Kenta Furuya, Hiroshige Shimizu, Muneyuki Sekiya, Takanori Ohata, Tomohiro Wada, Kazutoshi Isobe, Susumu Sakamoto, Yujiro Takai, Sakae Homma

Journal: Intern. Med.. 2015 ;54(16):2029-33.

 

Antiphospholipid syndrome (APS) is clinically characterized by arterial or venous thrombosis; however, non-thromboembolic lung manifestations, such as diffuse alveolar hemorrhage (DAH), have also been previously reported. DAH is relatively common in APS patients with systemic lupus ...

Last Updated: 17 Aug 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Antiphospholipid Syndrome" returned 132 free, full-text review articles on human participants. First 3 results:

[Cardiac Manifestations in Antiphospholipid Syndrome--A Brief Review of the Literature].
 

Author(s): Aleksandra Djoković, Ljudmila Stojanović

Journal: Srp Arh Celok Lek. ;143(5-6):346-53.

 

Antiphospholipid syndrome (APS) or Hughes syndrome represents a systemic autoimmune disorder characterized by arterial and/or venous thrombosis, multiple and recurrent fetal losses, accompanied by persistently elevated levels of antiphospholipid antibodies (aPL). This syndrome is ...

Last Updated: 11 Aug 2015

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Treatment of Thrombotic Antiphospholipid Syndrome: The Rationale of Current Management-An Insight into Future Approaches.
 

Author(s): Cecilia Beatrice Chighizola, Tania Ubiali, Pier Luigi Meroni

Journal: J Immunol Res. 2015 ;2015():951424.

 

Vascular thrombosis and pregnancy morbidity represent the clinical manifestations of antiphospholipid syndrome (APS), which is serologically characterized by the persistent positivity of antiphospholipid antibodies (aPL). Antiplatelet and anticoagulant agents currently provide the ...

Last Updated: 15 Jun 2015

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"New" antigenic targets and methodological approaches for refining laboratory diagnosis of antiphospholipid syndrome.
 

Author(s): Roberta Misasi, Antonella Capozzi, Agostina Longo, Serena Recalchi, Emanuela Lococo, Cristiano Alessandri, Fabrizio Conti, Guido Valesini, Maurizio Sorice

Journal: J Immunol Res. 2015 ;2015():858542.

 

Antiphospholipid antibodies (aPLs) are a heterogeneous group of antibodies directed against phospholipids or protein/phospholipid complexes. Currently, aPLs are assessed using either "solid-phase" assays that identify anticardiolipin antibodies and anti-β2-glycoprotein I antibodies ...

Last Updated: 15 Apr 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Predictors of Pregnancy Outcome in Systemic Lupus Erythematosus (SLE) and Antiphospholipid Syndrome (APS)
 

Status: Recruiting

Condition Summary: Systemic Lupus Erythematosus; Antiphospholipid Syndrome

 

Last Updated: 12 Apr 2016

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Last Updated: 26 May 2015

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Rivaroxaban in Thrombotic Antiphospholipid Syndrome
 

Status: Recruiting

Condition Summary: Antiphospholipid Syndrome

 

Last Updated: 30 Nov 2015

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