Alzheimer Disease Type 4

Common Name(s)

Alzheimer Disease Type 4

Alzheimer disease is a degenerative disease of the brain that causes gradual loss of memory, judgment, and ability to function socially. Alzheimer disease currently affects about 5 million people. About 75 percent of Alzheimer disease cases are classified as sporadic, which means they occur in people with no history of the disorder in their family. Although the cause of these cases is unknown, genetic changes are likely to play a role. Virtually all sporadic Alzheimer disease begins after age 65, and the risk of developing this condition increases as a person gets older.

The remaining cases of Alzheimer disease are familial, which means they are found in multiple members of a family. Familial Alzheimer disease can be divided into early-onset disease (symptoms begin before age 65) and late-onset disease (symptoms begin after age 65).

 

Advocacy and Support Organizations

 

Condition Specific Organizations

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Alzheimer Disease Type 4" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Alzheimer Disease Type 4" returned 1 free, full-text research articles on human participants. First 3 results:

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.
 

Author(s): W J Strittmatter, A M Saunders, D Schmechel, M Pericak-Vance, J Enghild, G S Salvesen, A D Roses

Journal: Proc. Natl. Acad. Sci. U.S.A.. 1993 Mar;90(5):1977-81.

 

Apolipoprotein E is immunochemically localized to the senile plaques, vascular amyloid, and neurofibrillary tangles of Alzheimer disease. In vitro, apolipoprotein E in cerebrospinal fluid binds to synthetic beta A4 peptide (the primary constituent of the senile plaque) with high avidity. ...

Last Updated: 8 Apr 1993

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Alzheimer Disease Type 4" returned 0 free, full-text review articles on human participants.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Intranasal AD4-H5-VTN as an Adenovirus Vaccine
 

Status: Recruiting

Condition Summary: Healthy Volunteer

 

Last Updated: 17 Jun 2014

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Experimental AD4-H5-VTN Vaccine in Healthy Volunteers
 

Status: Recruiting

Condition Summary: H5N1 Influenza

 

Last Updated: 6 Sep 2014

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Study of Safety and Immunogenicity of HIV Vaccines in Healthy Volunteers
 

Status: Recruiting

Condition Summary: Healthy Volunteer; HIV Vaccine

 

Last Updated: 9 Aug 2014

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