Acatalasemia

Common Name(s)

Acatalasemia

Acatalasemia, also known as acatalasia, is a metabolic disorder characterized by a total or near total loss of catalase activity in erythrocytes. About half of cases originate from ulcerating oral gangrenes, and these cases are referred to as having Takahara disease. Half-normal levels of catalase in heterozygotes is referred to as hypocatalasemia or hypocatalasia ({12:Ogata, 1991}).
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Acatalasemia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Acatalasemia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Acatalasemia" returned 4 free, full-text research articles on human participants. First 3 results:

Activities of superoxide dismutase and glutathione peroxidase in the red cells of Japanese acatalasemia blood.
 

Author(s): M Ogata, J Mizugaki, K Ueda, M Ikeda

Journal: Tohoku J. Exp. Med.. 1977 Sep;123(1):95-8.

 

The activities of superoxide dismutase and glutathione peroxidase in the red cells of normal and acatalasemia bloods were compared. Superoxide dismutase activity in the red cells of Japanese acatalasemia blood was higher than in normal control, while glutathione peroxidase activity ...

Last Updated: 29 Dec 1977

Go To URL
Activities of catalase in leucocytes and glucose-6-phosphate dehydrogenase in erythrocytes of hypocatalasemia and acatalasemia.
 

Author(s): M Ogata, J Mizugaki, K Taketa, S Takahara

Journal: Tohoku J. Exp. Med.. 1977 May;122(1):93-7.

 

Catalase activity in leucocytes was found to be half the normal value in hypocatalasemia and extremely low in acatalasemia. Glucose-6-phosphate dehydrogenase activity in erythrocytes was not significantly different between normal, hypocatalasemia and acatalasemia in three families ...

Last Updated: 29 Dec 1977

Go To URL
Residual catalase like protein in the erythrocytes of Japanese acatalasemia.
 

Author(s): M Ogata, J Mizugaki, S Takahara

Journal: Tohoku J. Exp. Med.. 1973 Sep;111(1):97-8.

 

Last Updated: 3 Apr 1974

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Acatalasemia" returned 2 free, full-text review articles on human participants. First 3 results:

Mammalian acatalasemia: the perspectives of bioinformatics and genetic toxicology.
 

Author(s): Masana Ogata, Da-Hong Wang, Keiki Ogino

Journal: Acta Med. Okayama. 2008 Dec;62(6):345-61.

 

The molecular defects in the catalase gene, levels of m-RNA and properties of the residual catalase studied by scientists are reviewed in human (Japanese, Swiss and Hungarian) and non-human (mouse and beagle dog) acatalasemia with reference to the bioinformatics. Japanese acatalasemia-I, ...

Last Updated: 5 Jan 2009

Go To URL
The oxidation of metallic mercury by catalase in relation to acatalasemia.
 

Author(s): M Ogata, H Aikoh

Journal: Ind Health. 1983 ;21(4):219-30.

 

Last Updated: 20 Feb 1984

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.